| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000159220 |
| Family | GT33 |
| Protein Properties | Length: 535 Molecular Weight: 60453.4 Isoelectric Point: 8.2497 |
| Chromosome | Chromosome/Scaffold: 001927175 Start: 1341 End: 5185 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT33 | 68 | 523 | 0 |
| QASLEVDIVAYGGSEPHSALLEHQSIHIHKMQQWQTFTRGLPNILRPFVLLIKAVTQFXMLLWFLCIKIPAPDVYLVQNPPSVPTLMAVKWASWLRKSAF IVDWHNFGYTLLALSLGRSSRFVAIYRCRLSFSFLIRFERYFGKMADGSLCVTRAMQHELAQNWGIKATVLYDQPPEFFRPASLEEKHKLFCRLDKNLRQ PLGVHDCTSTGSGEVNTDINDTLFTXLVGTDVTXKPHRPALIVSSTSWTPDEDFEILLEAAVMYDRRVAAILNEEDSTKEEVLWKDIHSGKQYLYPRLLF VITGKGPEKQKYEEKISRLHLKRVAFRTMWLSAEDYPLLLGSADLGVCLHTSSSGLDLPMKVVDMFGCGLPVCAVSYSCIKELVQVEKNGLLFSSSSELA DELLCTXFVIISLLXPVQMLFKGFPXACGSLKVLRNGALEMASSGRWATEWEEHAK | |||
| Full Sequence |
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| Protein Sequence Length: 535 Download |
| MAKARGLRGW XVTPRGKRGR ACVVVLGDIG RSPRMQYHAL SLARQSELLF FMRNLDLFVI 60 FXIECASQAS LEVDIVAYGG SEPHSALLEH QSIHIHKMQQ WQTFTRGLPN ILRPFVLLIK 120 AVTQFXMLLW FLCIKIPAPD VYLVQNPPSV PTLMAVKWAS WLRKSAFIVD WHNFGYTLLA 180 LSLGRSSRFV AIYRCRLSFS FLIRFERYFG KMADGSLCVT RAMQHELAQN WGIKATVLYD 240 QPPEFFRPAS LEEKHKLFCR LDKNLRQPLG VHDCTSTGSG EVNTDINDTL FTXLVGTDVT 300 XKPHRPALIV SSTSWTPDED FEILLEAAVM YDRRVAAILN EEDSTKEEVL WKDIHSGKQY 360 LYPRLLFVIT GKGPEKQKYE EKISRLHLKR VAFRTMWLSA EDYPLLLGSA DLGVCLHTSS 420 SGLDLPMKVV DMFGCGLPVC AVSYSCIKEL VQVEKNGLLF SSSSELADEL LCTXFVIISL 480 LXPVQMLFKG FPXACGSLKV LRNGALEMAS SGRWATEWEE HAKALILEVI SKNSD 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR00032 | argG | 2.0e-10 | 360 | 471 | 113 | + argininosuccinate synthase. argG in bacteria, ARG1 in Saccharomyces cerevisiae. There is a very unusual clustering in the alignment, with a deep split between one cohort of E. coli, H. influenzae, and Streptomyces, and the other cohort of eukaryotes, archaea, and the rest of the eubacteria [Amino acid biosynthesis, Glutamate family]. | ||
| cd03801 | GT1_YqgM_like | 2.0e-12 | 72 | 471 | 413 | + This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. | ||
| cd03794 | GT1_wbuB_like | 5.0e-13 | 93 | 471 | 388 | + This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase. | ||
| PLN02275 | PLN02275 | 0 | 16 | 471 | 456 | + transferase, transferring glycosyl groups | ||
| cd03816 | GT1_ALG1_like | 0 | 16 | 526 | 513 | + This family is most closely related to the GT1 family of glycosyltransferases. The yeast gene ALG1 has been shown to function as a mannosyltransferase that catalyzes the formation of dolichol pyrophosphate (Dol-PP)-GlcNAc2Man from GDP-Man and Dol-PP-Glc-NAc2, and participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. In humans ALG1 has been associated with the congenital disorders of glycosylation (CDG) designated as subtype CDG-Ik. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0009058 | biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI19390.1 | 0 | 16 | 533 | 10 | 482 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_173105.1 | 0 | 16 | 535 | 2 | 464 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
| RefSeq | XP_002283369.1 | 0 | 16 | 526 | 125 | 590 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002330745.1 | 0 | 16 | 528 | 2 | 467 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002532170.1 | 0 | 15 | 535 | 5 | 476 | beta1,4 mannosyltransferase, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DV132185 | 280 | 162 | 441 | 0 |
| GO921748 | 278 | 257 | 533 | 0 |
| GO872658 | 366 | 17 | 382 | 0 |
| GH271554 | 259 | 248 | 506 | 0 |
| JG909886 | 308 | 184 | 491 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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