Total Publications
131
A snapshot of our publication record and impact.
Total Publications
131
Most Significant
57
Highlight-tagged
15
Latest Year Output
2025 (8 pubs)
M Feidaki R^, Yan Y^, Yang B^, Argiriou A, Panas P, Kourkoutas Y, Hutkins R#, Yin Y#. (2026) Genomic characterization of three Lacticaseibacillus paracasei strains from Greek fermented olives reveals common and unique characteristics and three district clades, Applied and Environmental Microbiology, DOI: 10.1128/aem.00515-26
M Akresi JE^, Do TVT^, Cui Z^, Shanmugam NRS^, Moraïs S, Bayer EA, Auchtung JA, and Yin Y#. (2026) Limousia bacteria encode mucinolysome for mucin utilization in animal gut microbiomes. bioRxiv [Preprint]. 2025 Oct 14:2025.10.14.682383. Preprint link, Gut Microbes, doi: https://doi.org/10.1080/19490976.2026.2645267
P Feng X^, Patel R^, Yan Y^, Annabhemoju V^, Meinhardt L, Bailey B, Park S, Cohen S, Zhang D, Yin Y#. (2026) Chromosomal-scale and haplotype-resolved genome assembly of the first Trinitario hybrid cacao ICS 1, Scientific Data, doi: 10.1038/s41597-026-07054-0
P Tan H, Lou Y, Yan Y^, Meinhardt L, Bailey B, Gutierrez O, Park S, Cohen S, Zhang D, Yin Y#. (2025) Near T2T haplotype-resolved genomes of cacao (Theobroma cacao) variety CCN51. Scientific Data. doi: 10.1038/s41597-025-06480-w
M Hu L^, Zhang X^, Gao X, Yang M, Dong X, Cheng Y, Liang T, Yang B, Zhang Y, Yin Y#. (2025) Bacillus velezensis T971 genome informs starch degradation in tobacco. Frontiers in Microbiology. DOI 10.3389/fmicb.2025.1689015
M Yan Y^, Patel R^, Shanmugam NRS^, Akresi J^, Yin Y#. (2025) dbCAN-HGM: CAZyme gene clusters in gut microbiomes of diverse human populations. Nucleic Acids Res. DOI: 10.1093/nar/gkaf1185
M Khatri M^, Shanmugam NRS^, Zhang X^, Patel R^, and Yin Y#. (2025) AcrDB update: predicted 3D structures of anti-CRISPRs in human gut viromes. Protein Science. DOI: 10.1002/pro.70177
M Shanmugam NRS^, Yin Y#. (2025) CAZyme3D: a database of 3D structures for carbohydrate-active enzymes. Journal of Molecular Biology. doi.org/10.1016/j.jmb.2025.169001
P Feng X^, Permann C, Holzinger A, Yin Y#. (2024) High molecular weight DNA extraction from mucilage rich zygnematophycean green algae for long read DNA sequencing. BMC Methods. DOI: 10.1186/s44330-024-00018-z
M Zheng J, Huang L, Yi H, Yan Y, Zhang X, Akresi J, Yin Y#. (2024) Carbohydrate-active enzyme annotation in microbiomes using dbCAN. bioRxiv. Preprint link
P Nousias O^, Zheng J^, Li T^, Meinhardt L, Bailey B, Gutierrez O, Baruah IK, Cohen S, Zhang D, Yin Y#. (2024) Three de novo assembled wild cacao genomes from the Upper Amazon. Scientific Data. DOI: 10.1038/s41597-024-03215-1
P Li T^, Zheng J^, Nousias O^, Meinhardt L, Goenaga R, Zhang D, Yin Y#. (2024) The cherimoya genome reveals insights into the intra-specific divergence, the evolution of Magnoliales, and a putative gene cluster for acetogenin biosynthesis. Plants 13(5):636. doi
M Dexheimer S^, Shrestha N, Chapagain BS^, Bujarski J#, Yin Y#. (2024) Characterization of Multivariate RNAs Encapsidated During Infection by Two Bromoviruses Based on ViReMa. Pathogens 13(1):96. doi
M Yan Y^, Zheng J^, Zhang X^, Yin Y#. (2023) dbAPIS: a database of anti-prokaryotic immune system genes. Nucleic Acids Res. doi:10.1093/nar/gkad932
M Yang B*, Khatri M*, Zheng J, Deogun J, Yin Y#. (2023) Genome mining for anti-CRISPR operons using machine learning. Bioinformatics. doi:10.1093/bioinformatics/btad309
M Zheng J*, Ge Q*, Yan Y, Zhang X, Huang L, Yin Y#. (2023) dbCAN3: automated carbohydrate-active enzyme and substrate annotation. Nucleic Acids Res. doi:10.1093/nar/gkad328 ★ ESI Highly Cited Hot (Top 0.1%) Paper — Biology & Biochemistry
P Feng X*, Zheng J*, Irisarri I*, Yu H, Zheng B, Ali Z, de Vries S, Keller J, Fürst-Jansen J, Dadras A, Zegers J, Rieseberg TP, Ashok AD, Darienko T, Bierenbroodspot MJ, Gramzow L, Petroll R, Haas FB, Fernandez-Pozo N, Nousias O, Li T, Fitzek E, Grayburn WS, Rittmeier N, Permann C, Rümpler F, Archibald JM, Theißen G, Mower JP, Lorenz M, Buschmann H, von Schwartzenberg K, Boston L, Hayes RD, Daum C, Barry K, Grigoriev IV, Wang X, Li FW, Rensing SA, Ben-Ari J, Keren N, Mosquna A, Holzinger A, Delaux PM, Zhang C, Huang J, Mutwil M, de Vries J#, Yin Y#. (2023) Genomes of multicellular algal sisters to land plants illuminate signaling network evolution. Nature Genetics. doi.org/10.1038/s41588-024-01737-3. Highlighted at Nature Plants. ★ ESI Highly Cited (Top 1%) — Molecular Biology & Genetics
M Yang B^, Zheng J^, Yin Y#. (2022) AcaFinder: genome mining of anti-CRISPR associated genes in bacteria and phages. mSystems. doi:10.1128/msystems.00817-22
M Zheng J^, Hu B^, Zhang X^, Ge Q^, Yan Y^, Piyush V^, Huang L, Yin Y#. (2022) dbCAN-seq update: CAZyme gene clusters and substrates in microbiomes. Nucleic Acids Res. doi:10.1093/nar/gkac1068
M Li T^, Yin Y#. (2022) Critical assessment of pan-genomics of metagenome-assembled genomes. Briefings in Bioinformatics. doi:10.1093/bib/bbac413
P Zheng J^, Meinhardt L, Goenaga R, Matsumoto T, Zhang D, Yin Y#. (2021) The chromosome-level rambutan genome reveals a significant role of segmental duplication in the expansion of resistance genes. Horticulture Research 9:uhac014. doi
M Zheng B^, He Y+, Zhang P+, Huo YX, Yin Y#. (2021) Polyphenol utilization proteins in human gut microbiome. Applied and Environmental Microbiology. doi Editor Spotlight Paper
M Cheng X*, Yang B^*, Zheng J^, Wei H, Feng X^, Yin Y#. (2021) Cadmium stress triggers significant metabolic reprogramming in Enterococcus faecium CX 2-6. Computational and Structural Biotechnology Journal. doi
M Peterson D^, Li T^, Calvo AM, Yin Y#. (2021) Categorization of orthologous gene clusters in 92 Ascomycota genomes reveals functions important for phytopathogenicity. Journal of Fungi 7(5):337. doi
P Zheng J^, Meinhardt L, Goenaga R, Zhang D, Yin Y#. (2021) The chromosome-level genome of dragon fruit reveals whole genome duplication and chromosomal co-localization of betacyanin biosynthetic genes. Horticulture Research 8:63. doi
P Feng X^, Holzinger A, Permann C, Anderson C, Yin Y#. (2021) Characterization of two Zygnema strains (SAG 698-1a and SAG 698-1b) and a rapid method to estimate nuclear genome size of Zygnematophycean green algae. Frontiers in Plant Science 12:610381. doi
M Huang L^*, Yang B^*, Yi H^, Asif A, Wang J, Lithgow T, Zhang H, Minhas F, Yin Y#. (2020) AcrDB: a database of anti-CRISPR operons in prokaryotes and viruses. Nucleic Acids Res. doi:10.1093/nar/gkaa857
M Ausland C^, Zheng J^, Yi H^, Yang B^, Li T^, Feng X^, Zheng B^, Yin Y#. (2020) dbCAN-PUL: a database of experimentally characterized CAZyme gene clusters and their substrates. Nucleic Acids Res. doi:10.1093/nar/gkaa742 ★ ESI Highly Cited (Top 1%) — Biology & Biochemistry
P Fitzek E.^, Balazic R.+, Yin Y#. (2020) Bioinformatics Analysis of Plant Cell Wall Evolution. In: Popper Z. (eds) The Plant Cell Wall. Methods in Molecular Biology 2149:483–502. Humana, New York. doi
M Cao H^, Shimura Y, Steffen MM, Yang Z, Lu J, Joel A, Jenkins L, Kawachi M, Yin Y#, Garcia-Pichel F#. (2020) The trait repertoire enabling cyanobacteria to bloom assessed through comparative genomic complexity and metatranscriptomics. mBio 11:e01155-20. doi
M Yi H^, Huang L^, Yang B^, Zhang H, Yin Y#. (2020) AcrFinder: genome mining anti-CRISPR operons in prokaryotes and their viruses. Nucleic Acids Res. doi:10.1093/nar/gkaa351
P Orton L^, Fitzek E^, Feng X^, Grayburn SW, Mower JP, Liu K, Zhang C, Duvall MR, Yin Y#. (2020) Zygnema circumcarinatum UTEX 1559 chloroplast and mitochondrial genomes provide insight into land plant evolution. Journal of Experimental Botany. doi:10.1093/jxb/eraa149
M Xu J, Zhang H, Zheng J^, Dovoedo P^, Yin Y#. (2019) eCAMI: simultaneous classification and motif identification for enzyme annotation. Bioinformatics. doi:10.1093/bioinformatics/btz908
M Yin Y#, Yang B^, Entwistle S^. (2019) Bioinformatics identification of anti-CRISPR loci using homology, guilt-by-association, and CRISPR self-targeting spacer approaches. mSystems. doi:10.1128/mSystems.00455-19
P Fitzek E^, Orton F^, Entwistle S^, Grayburn SW, Ausland C^, Duvall DR, Yin Y#. (2019) Cell wall enzymes in Zygnema circumcarinatum UTEX 1559 respond to osmotic stress in a plant-like fashion. Frontiers in Plant Science. doi:10.3389/fpls.2019.00732
M Entwistle S^, Li X^, Yin Y#. (2019) Orphan genes shared by pathogenic genomes are more associated with bacterial pathogenicity. mSystems 4(1):e00290-18. doi:10.1128/mSystems.00290-18
M Zhang H*, Yohe T*+, Huang L, Entwistle S^, Wu P, Yang Z, Busk P, Xu Y, Yin Y#. (2018) dbCAN2: a meta server for automated carbohydrate-active enzyme annotation. Nucleic Acids Res. (Web server issue 2018) 46(W1):W95–W101. doi:10.1093/nar/gky418 ★ ESI Highly Cited (Top 1%) — Biology & Biochemistry [95+ citations]
M Huang L, Zhang H, Wu P, Entwistle S+, Li X^, Yohe T+, Yi H, Yang Z, Yin Y#. (2017) dbCAN-seq: a database of carbohydrate-active enzyme (CAZyme) sequence and annotation. Nucleic Acids Res. (database issue 2018) 46(D1):D516–D521. doi:10.1093/nar/gkx894
M Huo L, Zhang H, Huo X, Yang Y^, Li X^, Yin Y#. (2017) pHMM-tree: Phylogeny of Profile Hidden Markov Models. Bioinformatics 33(7):1093–1095. doi:10.1093/bioinformatics/btw779
M Ekstrom A+, Yin Y#. (2016) ORFanFinder: automated identification of taxonomically restricted orphan genes. Bioinformatics 32(13):2053–2055. doi:10.1093/bioinformatics/btw122
M Hu L, Taujale R^, Song J, Guo J, Yin Y#. (2016) Draft genome sequence of Talaromyces verruculosus ("Penicillium verruculosum") strain TS63-9, a fungus with great potential for industrial production of polysaccharide-degrading enzymes. Journal of Biotechnology 219:5–6. doi
M Nguyen M+, Ekstrom A+, Li X^, Yin Y#. (2015) HGT-Finder: a new tool for horizontal gene transfer finding and application to Aspergillus genomes. Toxins 7(10):4035–4053. doi:10.3390/toxins7104035 Highly accessed · 14+ citations
P Taujale R^, Yin Y#. (2015) Glycosyltransferase family 43 is also found in early eukaryotes and has three subfamilies in Charophycean green algae. PLoS ONE. doi:10.1371/journal.pone.0128409
P Ekstrom A+, Taujale R^, McGinn N+, Yin Y#. (2014) PlantCAZyme: a database for plant carbohydrate-active enzymes. Database: The Journal of Biological Databases and Curation. doi:10.1093/database/bau079 NIU Undergraduate Research & Artistry Day Award · 17+ citations
M Cao H^, Yin Y#. (2014) Rapid evolution of cellulosome modules by comparative analyses of five Clostridiales genomes. Bioenergy Research 7:1369–1381. doi
P Yin Y#, Johns MA, Cao H^, Rupani M^. (2014) A survey of the genomes and transcriptomes of diverse plants and algae reveals new insights into the evolution and function of the cellulose synthase superfamily. BMC Genomics 15:260. doi Highly accessed · 34+ citations
M Cao H^, Shimura Y, Masanobu K, Yin Y#. (2014) Draft genome sequence of the toxic bloom-forming cyanobacterium Aphanizomenon flos-aquae NIES-81. Genome Announc. 2(1):e00044-14. doi
M Ma Q*, Yin Y*, Schell M, Li G, Xu Y. (2013) Computational analyses of transcriptomic data reveal the dynamic organization of the Escherichia coli chromosome under different conditions. Nucleic Acids Research 41(11):5594–5603. doi
P Wang S*, Yin Y*, Ma Q, Tang X, Xu Y. Genome-scale identification of cell-wall related genes in Arabidopsis based on co-expression network analysis. BMC Plant Biology 2012;12:138. 39+ citations
P Yin Y*, Mao X*, Yang JC, Chen X, Xu Y. dbCAN: a web resource for automated carbohydrate-active enzyme annotation. Nucleic Acids Res. (web server issue 2012) 40:W445–W451. doi ★ ESI Highly Cited (Top 1%) — Biology & Biochemistry · DOE Key Advance for Biofuels Production · 832+ citations
P Yin Y, Huang J, Gu X, Bar-Peled M, Xu Y. (2011) Evolution of plant nucleotide-sugar interconversion enzymes. PLoS One 6(11):e27995. PubMed PMCID: PMC3220709. 40+ citations
M Zhang H*, Yin Y*, Olman V, Xu Y. (2012) Genomic arrangement of regulons in bacterial genomes. PLoS One 7(1):e29496. PubMed PMCID: PMC3250446. 40+ citations
P Yin Y, Mohnen D, Xu Y, Hahn M. (2011) Glycosyltransferase Family 8 (GT8). Book chapter of Plant Cell Wall Polysaccharides: Biosynthesis and Bioengineering. Annual Plant Review series (Blackwell) 41:167–212. 16+ citations
P Yin Y, Chen H, Hahn MG, Mohnen D, Xu Y. (2010) Evolution and function of the plant cell wall synthesis-related glycosyltransferase family 8. Plant Physiol. 153(4):1729–1746. PubMed PMCID: PMC2923890. 83+ citations
M Yin Y*, Zhang H*, Olman V, Xu Y. (2010) Genomic arrangement of bacterial operons is constrained by biological pathways encoded in the genome. PNAS 107(14):6310–6315. PubMed PMCID: PMC2851940. 38+ citations
P Yin Y, Huang J, Xu Y. (2009) The cellulose synthase superfamily in fully sequenced plants and algae. BMC Plant Biol. 9:99. PubMed PMCID: PMC3091534. Highly accessed · 115+ citations
P Shen H*, Yin Y*, Chen F, Xu Y, Dixon R. (2009) A bioinformatic analysis of NAC genes for plant cell wall development in relation to lignocellulosic bioenergy production. Bioenergy Research 2(4):217–232. 112+ citations
M Yin Y, Fischer D. (2008) Identification and investigation of ORFans in the viral world. BMC Genomics 9:24. PubMed PMCID: PMC2245933. 78+ citations
M Yin Y, Fischer D. (2006) On the origin of microbial ORFans: quantifying the strength of the evidence for viral lateral transfer. BMC Evol Biol. 6:63. PubMed PMCID: PMC1559721. 52+ citations
Feidaki R^, Yan Y^, Yang B^, Argiriou A, Panas P, Kourkoutas Y, Hutkins R#, Yin Y#. (2026) Genomic characterization of three Lacticaseibacillus paracasei strains from Greek fermented olives reveals common and unique characteristics and three district clades. Applied and Environmental Microbiology. doi: 10.1128/aem.00515-26
Feng X^, Patel R^, Yan Y^, Annabhemoju V^, Meinhardt L, Bailey B, Park S, Cohen S, Zhang D, Yin Y#. (2026) Chromosomal-scale and haplotype-resolved genome assembly of the first Trinitario hybrid cacao ICS 1. Scientific Data doi: 10.1038/s41597-026-07054-0
Chen H, …, Zhang X^, Lin X, Yin Y, Huang X, Zheng J, Liang T. (2026) Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation-informed Protein Language Model. Advanced Science doi:10.1002/advs.202516332
Tan H, Lou Y, Yan Y, Meinhardt L, Bailey B, Gutierrez O, Park S, Cohen S, Zhang D, Yin Y#. (2025) Near T2T haplotype-resolved genomes of cacao (Theobroma cacao) variety CCN51. Scientific Data. doi: 10.1038/s41597-025-06480-w
Hu L^, Zhang X^, Gao X, Yang M, Dong X, Cheng Y, Liang T, Yang B, Zhang Y, Yin Y#. (2025) Bacillus velezensis T971 genome informs starch degradation in tobacco. Frontiers in Microbiology. DOI 10.3389/fmicb.2025.1689015
Akresi JE^, Do TVT^, Cui Z^, Shanmugam NRS^, Moraïs S, Bayer EA, Auchtung JA, and Yin Y#. (2026) Limousia bacteria encode mucinolysome for mucin utilization in animal gut microbiomes. bioRxiv [Preprint]. 2025 Oct 14:2025.10.14.682383. Preprint link, Gut Microbes, doi: https://doi.org/10.1080/19490976.2026.2645267
Yan Y, Patel R, Shanmugam NRS, Akresi J, Yin Y#. (2025) dbCAN-HGM: CAZyme gene clusters in gut microbiomes of diverse human populations. Nucleic Acids Res. DOI: 10.1093/nar/gkaf1185
Lyu H, Song J, Yin Y, Wang ML, Matsumoto T, Annabhemoju V, Meinhardt LW, Park S, Lim S, Zhang D, Yu Q. (2025) A chromosome-level genome assembly of Coffea arabica L. var. 'Kona Typica'. Scientific Data 12(1):1314. doi: 10.1038/s41597-025-05658-6
Li W, Huang B, Guo M, Zeng Z, Cai T, Feng L, Zhang X^, Guo L, Jiang X, Yin Y, Wang E, Huang X, Zheng J. (2025) Unveiling the Evolution of Antimicrobial Peptides in Gut Microbes via Foundation Model-Powered Framework. Cell Reports 44(6):115773. doi: 10.1016/j.celrep.2025.115773
Khatri M^, Shanmugam NRS^, Zhang X^, Patel R^, and Yin Y#. (2025) AcrDB update: predicted 3D structures of anti-CRISPRs in human gut viromes. Protein Science. DOI: 10.1002/pro.70177
Shanmugam NRS^, Yin Y#. (2025) CAZyme3D: a database of 3D structures for carbohydrate-active enzymes. Journal of Molecular Biology. doi.org/10.1016/j.jmb.2025.169001
Feng X^, Permann C, Holzinger A, Yin Y#. (2024) High molecular weight DNA extraction from mucilage rich zygnematophycean green algae for long read DNA sequencing. BMC Methods. DOI: 10.1186/s44330-024-00018-z
Kang C, Zhang H, Yin Y. (2024) A dual-modality complex-valued fusion method for predicting side effects of drug-drug interactions based on graph neural network. IEEE Journal of Biomedical and Health Informatics. DOI: 10.1109/JBHI.2024.3422673
Khatri M, Yin Y, Deogun J. (2024) Enhancing Interpretability In Medical Image Classification By Integrating Formal Concept Analysis With Convolutional Neural Networks. Biomimetics 9(7):421. doi
Li M, Guo H, Wang K, Kang C, Yin Y, Zhang H. (2024) AVBAE-MODFR: A novel deep learning framework of embedding and feature selection on multi-omics data for pan-cancer classification. Computers in Biology and Medicine 177:108614. doi: 10.1016/j.compbiomed.2024.108614
Zheng J, Huang L, Yi H, Yan Y, Zhang X, Akresi J, Yin Y#. (2024) Carbohydrate-active enzyme annotation in microbiomes using dbCAN. bioRxiv. Preprint link
Nousias O^, Zheng J^, Li T^, Meinhardt L, Bailey B, Gutierrez O, Baruah IK, Cohen S, Zhang D, Yin Y#. (2024) Three de novo assembled wild cacao genomes from the Upper Amazon. Scientific Data. DOI: 10.1038/s41597-024-03215-1
Zhan X, Yin Y, Zhang H. (2024) BERMAD: batch effect removal for single-cell RNA-seq data using a multi-layer adaptation autoencoder with dual-channel framework. Bioinformatics. doi:10.1093/bioinformatics/btae127
Li T^, Zheng J^, Nousias O^, Meinhardt L, Goenaga R, Zhang D, Yin Y#. (2024) The cherimoya genome reveals insights into the intra-specific divergence, the evolution of Magnoliales, and a putative gene cluster for acetogenin biosynthesis. Plants 13(5):636. doi
Dexheimer S^, Shrestha N, Chapagain BS^, Bujarski J#, Yin Y#. (2024) Characterization of Multivariate RNAs Encapsidated During Infection by Two Bromoviruses Based on ViReMa. Pathogens 13(1):96. doi
Feng X*, Zheng J*, Irisarri I*, Yu H, Zheng B, Ali Z, de Vries S, Keller J, Fürst-Jansen J, Dadras A, Zegers J, Rieseberg TP, Ashok AD, Darienko T, Bierenbroodspot MJ, Gramzow L, Petroll R, Haas FB, Fernandez-Pozo N, Nousias O, Li T, Fitzek E, Grayburn WS, Rittmeier N, Permann C, Rümpler F, Archibald JM, Theißen G, Mower JP, Lorenz M, Buschmann H, von Schwartzenberg K, Boston L, Hayes RD, Daum C, Barry K, Grigoriev IV, Wang X, Li FW, Rensing SA, Ben-Ari J, Keren N, Mosquna A, Holzinger A, Delaux PM, Zhang C, Huang J, Mutwil M, de Vries J#, Yin Y#. (2023/2024) Genomes of multicellular algal sisters to land plants illuminate signaling network evolution. Nature Genetics. doi.org/10.1038/s41588-024-01737-3. Highlighted at Nature Plants. ★ ESI Highly Cited (Top 1%) — Molecular Biology & Genetics
Han M, Yin Y, Zhang H, Wang H. (2023) Hierarchical Semantic Augmentation Graph Neural Network for Drug-Disease Association Prediction. IEEE BIBM 2023. DOI: 10.1109/BIBM58861.2023.10385961
Quan X, Guo X, Zhang H, Han M, Li Z, and Yin Y. (2023) Unsupervised Feature Selection by Fusing Spectral Clustering and Locality Preserving Projection. IEEE BIBM 2023. DOI: 10.1109/BIBM58861.2023.10385296
Yan Y^, Zheng J^, Zhang X^, Yin Y#. (2023) dbAPIS: a database of anti-prokaryotic immune system genes. Nucleic Acids Res. doi:10.1093/nar/gkad932
Sandesh SP, Zheng J^, Yin Y, Lorber S, Puel O, Dhingra S, Espeso EA, Calvo AM. (2023) Homeobox Transcription Factor HbxA Influences Expression of over One Thousand Genes in the Model Fungus Aspergillus nidulans. PLoS ONE 18(7):e0286271. doi
Han M, Li W, Zhang H, Yin Y. (2023) Semantic-guided Graph Neural Network for Heterogeneous Graph Embedding. Expert Systems with Applications 232:120810. doi
Yang B*, Khatri M*, Zheng J, Deogun J, Yin Y#. (2023) Genome mining for anti-CRISPR operons using machine learning. Bioinformatics. doi:10.1093/bioinformatics/btad309
Zheng J*, Ge Q*, Yan Y, Zhang X, Huang L, Yin Y#. (2023) dbCAN3: automated carbohydrate-active enzyme and substrate annotation. Nucleic Acids Res. doi:10.1093/nar/gkad328 ★ ESI Highly Cited Hot (Top 0.1%) — Biology & Biochemistry
Huang W, Zhang H, Li Z, and Yin Y. (2022) Mutual Information Estimation-Based Disentangled Representation Network for Medical Image Fusion. IEEE BIBM 2022, Las Vegas, pp. 991–998. doi: 10.1109/BIBM55620.2022.9995221 Best Student Paper Award
Yang B^, Zheng J^, Yin Y#. (2022) AcaFinder: genome mining of anti-CRISPR associated genes in bacteria and phages. mSystems. doi:10.1128/msystems.00817-22
Zheng J^, Hu B^, Zhang X^, Ge Q^, Yan Y^, Piyush V^, Huang L, Yin Y#. (2022) dbCAN-seq update: CAZyme gene clusters and substrates in microbiomes. Nucleic Acids Res. doi:10.1093/nar/gkac1068
Wei H, Li Y, Yan J, Peng S, Wei S, Yin Y, Li K, Cheng X. (2022) Root cell wall remodeling: a way for exopolysaccharides to mitigate cadmium toxicity in rice seedling. Journal of Hazardous Materials.
Li W, Zhang H, Li M, Han M, Yin Y. (2022) MGEGFP: a multi-view graph embedding method for gene function prediction based on adaptive estimation with GCN. Briefings in Bioinformatics. doi:10.1093/bib/bbac333
Li T^, Yin Y#. (2022) Critical assessment of pan-genomics of metagenome-assembled genomes. Briefings in Bioinformatics. doi:10.1093/bib/bbac413
Zheng J^, Meinhardt L, Goenaga R, Matsumoto T, Zhang D, Yin Y#. (2021) The chromosome-level rambutan genome reveals a significant role of segmental duplication in the expansion of resistance genes. Horticulture Research 9:uhac014. doi
Wang X, Wang J, Huang S, Zhang H, Yin Y. (2021) HDMC: a novel deep learning based framework for removing batch effects in single-cell RNA-seq data. Bioinformatics. doi:10.1093/bioinformatics/btab821
Zheng B^, He Y+, Zhang P+, Huo YX, Yin Y#. (2021) Polyphenol utilization proteins in human gut microbiome. Applied and Environmental Microbiology. doi Editor Spotlight Paper
Kang C, Zhang H, Liu Z, Huang S, Yin Y. (2021) LR-GNN: a graph neural network based on link representation for predicting molecular associations. Briefings in Bioinformatics. doi:10.1093/bib/bbab513
Jin C, Shi Z, Zhang H, and Yin Y. (2021) Predicting lncRNA–protein interactions based on graph autoencoders and collaborative training. IEEE BIBM 2021.
Li W, Zhang H, Zhao Q, Liu J, and Yin Y. (2021) Adversarial Dual-Channel Variational Graph Autoencoder for Synthetic Lethality Prediction in Human Cancers. IEEE BIBM 2021.
Cheng X*, Yang B^*, Zheng J^, Wei H, Feng X^, Yin Y#. (2021) Cadmium stress triggers significant metabolic reprogramming in Enterococcus faecium CX 2-6. Computational and Structural Biotechnology Journal. doi
Shi Z, Zhang H, Jin C, Quan X, Yin Y. (2021) A representation learning model based on variational inference and graph autoencoder for predicting lncRNA-disease associations. BMC Bioinformatics 22:136. doi
Peterson D^, Li T^, Calvo AM, Yin Y#. (2021) Categorization of orthologous gene clusters in 92 Ascomycota genomes reveals functions important for phytopathogenicity. Journal of Fungi 7(5):337. doi
Zheng J^, Meinhardt L, Goenaga R, Zhang D, Yin Y#. (2021) The chromosome-level genome of dragon fruit reveals whole genome duplication and chromosomal co-localization of betacyanin biosynthetic genes. Horticulture Research 8:63. doi
Feng X^, Holzinger A, Permann C, Anderson C, Yin Y#. (2021) Characterization of two Zygnema strains (SAG 698-1a and SAG 698-1b) and a rapid method to estimate nuclear genome size of Zygnematophycean green algae. Frontiers in Plant Science 12:610381. doi
Li W, Zhao Q, Zhang H, Quan X, Xu J, and Yin Y. (2021) Bayesian Multi-scale Convolutional Neural Network for Motif Occupancy Identification. IEEE BIBM 2020, pp. 293–298. doi: 10.1109/BIBM49941.2020.9313556
Huang L^*, Yang B^*, Yi H^, Asif A, Wang J, Lithgow T, Zhang H, Minhas F, Yin Y#. (2020) AcrDB: a database of anti-CRISPR operons in prokaryotes and viruses. Nucleic Acids Res. doi:10.1093/nar/gkaa857
Ausland C^, Zheng J^, Yi H^, Yang B^, Li T^, Feng X^, Zheng B^, Yin Y#. (2020) dbCAN-PUL: a database of experimentally characterized CAZyme gene clusters and their substrates. Nucleic Acids Res. doi:10.1093/nar/gkaa742 ★ ESI Highly Cited (Top 1%) — Biology & Biochemistry
Fitzek E.^, Balazic R.+, Yin Y#. (2020) Bioinformatics Analysis of Plant Cell Wall Evolution. In: Popper Z. (eds) The Plant Cell Wall. Methods in Molecular Biology, vol 2149. Humana, New York. doi
Cao H^, Shimura Y, Steffen MM, Yang Z, Lu J, Joel A, Jenkins L, Kawachi M, Yin Y#, Garcia-Pichel F#. (2020) The trait repertoire enabling cyanobacteria to bloom assessed through comparative genomic complexity and metatranscriptomics. mBio 11:e01155-20. doi
Wang X, Yi H, Wang J, Zhan D, Yin Y, Zhang H. (2020) GDASC: A GPU parallel based web server for detecting hidden batch factors. Bioinformatics. doi:10.1093/bioinformatics/btaa427
Yi H^, Huang L^, Yang B^, Zhang H, Yin Y#. (2020) AcrFinder: genome mining anti-CRISPR operons in prokaryotes and their viruses. Nucleic Acids Res. doi:10.1093/nar/gkaa351
Orton L^, Fitzek E^, Feng X^, Grayburn SW, Mower JP, Liu K, Zhang C, Duvall MR, Yin Y#. (2020) Zygnema circumcarinatum UTEX 1559 chloroplast and mitochondrial genomes provide insight into land plant evolution. Journal of Experimental Botany. doi:10.1093/jxb/eraa149
Becker B, Feng X^, Yin Y, Holzinger A. (2020) Desiccation tolerance in streptophyte algae and the algae to land plant transition: Evolution of LEA and MIP protein families within the Viridiplantae. Journal of Experimental Botany. doi:10.1093/jxb/eraa105
Su X, Xu J, Yin Y, Quan X, Zhang H. (2019) Antimicrobial Peptide Identification Using Multi-scale Convolutional Network. BMC Bioinformatics 20:730. doi
Xu J, Zhang H, Zheng J^, Dovoedo P^, Yin Y#. (2019) eCAMI: simultaneous classification and motif identification for enzyme annotation. Bioinformatics. doi:10.1093/bioinformatics/btz908
Li W, Yin Y, Quan X, Zhang H. (2019) Gene Expression Value Prediction Based on XGBoost Algorithm. Frontiers in Genetics. doi
Satterlee T, Entwistle S, Yin Y, Cary J, Lebar M, Losada L, Calvo A. (2019) rmtA-Dependent Transcriptome and its Role in Secondary Metabolism, Environmental Stress, and Virulence in Aspergillus flavus. G3: Genes Genomes Genetics. doi
Yin Y#, Yang B^, Entwistle S^. (2019) Bioinformatics identification of anti-CRISPR loci using homology, guilt-by-association, and CRISPR self-targeting spacer approaches. mSystems. doi:10.1128/mSystems.00455-19
Fitzek E^, Orton F^, Entwistle S^, Grayburn SW, Ausland C^, Duvall DR, Yin Y#. (2019) Cell wall enzymes in Zygnema circumcarinatum UTEX 1559 respond to osmotic stress in a plant-like fashion. Frontiers in Plant Science. doi
Han W, Fan X, Teng L, Kaczurowski M, Zhang X, Xu D, Yin Y, Ye X. (2018/2019) Classification, Evolution and Function of putative Xylosyltransferases from Algae. Protoplasma. doi:10.1007/s00709-019-01358-2
Entwistle S^, Li X^, Yin Y#. (2019) Orphan genes shared by pathogenic genomes are more associated with bacterial pathogenicity. mSystems 4(1):e00290-18. doi
Cary J, Entwistle S, Satterlee T, Mack B, Gilbert M, Chang P, Scharfenstein L, Yin Y, Calvo A. (2018) The transcriptional regulator Hbx1 affects the expression of thousands of genes in the aflatoxin-producing fungus Aspergillus flavus. G3: Genes Genomes Genetics.
Wu G, Jurick W, Yin G, Yu J, Peng H, Gaskins V, Yin Y, Hua S, Peter K, Bennett J. (2018) Penicillium expansum and Penicillium solitum comparative genomics yields new insights into phylogeny and candidate genes involved in postharvest apple-fungus interactions. PeerJ. DOI: 10.7287/peerj.preprints.27430v1
Lyu Q*, Zhang K, Zhu Q, Li Z, Liu Y, Fitzek E^, Yohe Y+, Zhao L, Li W, Liu T, Yin Y, Liu W. (2018) Structural and biochemical characterization of a multidomain alginate lyase reveals a novel role of CBM32 in CAZymes. Biochim Biophys Acta 1862(9):1862–1869.
Driscoll CB, Meyer KA, Šulčius S, Brown NM, Dick GJ, Cao H^, Gasiūnas G, Timinskas A, Yin Y, Landry ZC, Otten TG, Davis TW, Watson SB, Dreher TW. (2018) A closely-related clade of globally distributed bloom-forming cyanobacteria within the Nostocales. Harmful Algae 77:93–107.
Zhang H*, Yohe T*+, Huang L, Entwistle S^, Wu P, Yang Z, Busk P, Xu Y, Yin Y#. (2018) dbCAN2: a meta server for automated carbohydrate-active enzyme annotation. Nucleic Acids Res. (Web server issue 2018) 46(W1):W95–W101. doi:10.1093/nar/gky418 ★ ESI Highly Cited (Top 1%) — Biology & Biochemistry
Han W, Ibarra G, Gupta M, Yin Y, Elsawa S. (2018) Elevated Expression of GLI3 in Germinal Center Diffuse Large B Cell Lymphoma. Leukemia and Lymphoma. doi
Huang L, Zhang H, Wu P, Entwistle S+, Li X^, Yohe T+, Yi H, Yang Z, Yin Y#. (2017) dbCAN-seq: a database of carbohydrate-active enzyme (CAZyme) sequence and annotation. Nucleic Acids Res. (database issue 2018) 46(D1):D516–D521. doi:10.1093/nar/gkx894
Yang X, …, Fitzek E^, …, Yin Y, …, Tuskan GA. (2017) The Kalanchoë genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism. Nature Communications 8:1899. doi
Jiang X, Zhang H, Quan X, Yin Y. (2017) A Heterogeneous Networks Fusion Algorithm Based on Local Topological Information for Neurodegenerative Disease. Current Bioinformatics 12(5):387–397.
Jiang X, Quan X, Zhang H, Zhan D, Yin Y. (2017) Disease-related Gene Module Detection Based on A Multi-label Propagation Clustering Algorithm. PLoS One 12(5):e0178006. doi
Huo L, Zhang H, Huo X, Yang Y^, Li X^, Yin Y#. (2017) pHMM-tree: Phylogeny of Profile Hidden Markov Models. Bioinformatics 33(7):1093–1095. doi:10.1093/bioinformatics/btw779
Wysocki W, Riuz-Sanches E, Yin Y, Duvall M. (2016) The floral transcriptomes of four bamboo species (Bambusoideae; Poaceae): support for common ancestry among woody bamboos. BMC Genomics 17:384. doi
Yu J, Wu G, Jurick WM Jr, Gaskins VL, Yin Y, Yin G, Bennett JW, Shelton DR. (2016) Genome sequence of Penicillium solitum RS1, which causes postharvest apple decay. Genome Announc. 4(3):e00363-16. doi
Ekstrom A+, Yin Y#. (2016) ORFanFinder: automated identification of taxonomically restricted orphan genes. Bioinformatics 32(13):2053–2055. doi
Hu L, Taujale R^, Song J, Guo J, Yin Y#. (2016) Draft genome sequence of Talaromyces verruculosus ("Penicillium verruculosum") strain TS63-9. Journal of Biotechnology 219:5–6. doi
Yang X, Leeben-Mack J, Chen F, Yin Y. (2015) Plant Comparative and Functional Genomics. International Journal of Genomics 2015:924369. doi
Nguyen M+, Ekstrom A+, Li X^, Yin Y#. (2015) HGT-Finder: a new tool for horizontal gene transfer finding and application to Aspergillus genomes. Toxins 7(10):4035–4053. doi Highly accessed
Cary JW*, Han Z*, Yin Y*, Lohmar JM, Shantappa S, Harris-Coward PY, Mack B, Ehrlich KC, Wei Q, Arroyo-Manzanares N, Uka V, Vanhaecke L, Bhatnagar D, Yu J, Nierman WC, Johns MA, Sorensen D+, Shen H^, De Saeger S, Diana Di Mavungu J, Calvo AM. (2015) Transcriptome analysis of Aspergillus flavus reveals veA-dependent regulation of secondary metabolite gene clusters, including the novel aflavarin cluster. Eukaryot Cell 14:983–997. doi Articles of Significant Interest — Editors' Selection
Taujale R^, Yin Y#. (2015) Glycosyltransferase family 43 is also found in early eukaryotes and has three subfamilies in Charophycean green algae. PLoS ONE. doi
Cao H^, Ekstrom A+, Yin Y#. (2015) Plant carbohydrate active enzyme (CAZyme) repertoires: a comparative study. Invited book chapter in Advances in the Understanding of Biological Sciences using Next Generation Sequencing (NGS) Approaches, Springer. doi, pp. 115–134.
Cui J, Yin Y, Ma Q, Wang G, Olman V, Zhang Y, Chou WC, Hong CS, Zhang C, Cao S, Mao X, Li Y, Qin S, Zhao S, Jiang J, Hastings P, Li F, Xu Y. (2015) Comprehensive Characterization of the Genomic Alterations in Human Gastric Cancer. Int J Cancer. doi
Ekstrom A+, Taujale R^, McGinn N+, Yin Y#. (2014) PlantCAZyme: a database for plant carbohydrate-active enzymes. Database: The Journal of Biological Databases and Curation. doi NIU Undergraduate Research & Artistry Day Award
Zhao Q, Zeng Y, Yin Y, Pu Y, Jackson LA, Engle NL, Martin MZ, Tschaplinski TJ, Ding SY, Ragauskas AJ, Dixon RA. (2014) Pinoresinol reductase 1 impacts lignin distribution during secondary cell wall biosynthesis in Arabidopsis. Phytochemistry. doi
Yu J, Jurick WM, Cao H^, Yin Y, Gaskins VL, Losada L, Zafar N, Kim M, Bennett JW, Nierman WC. (2014) Draft genome sequence of Penicillium expansum (R19) that causes postharvest decay of apple fruit. Genome Announcements 2(3):e00635-14. doi
Zhou C, Ma Q, Mao X, Yin Y#, Xu Y#. (2014) New Insights Revealed through Comparative Genomic Analysis of 40 Clostridium Genomes. Bioenergy Research 7:1481–1492. doi
Zhou C, Mao F, Yin Y, Huang J, Gogarten JP, et al. (2014) AST: An Automated Sequence-Sampling Method for Improving the Taxonomic Diversity of Gene Phylogenetic Trees. PLoS ONE 9(6):e98844. doi
Cao H^, Yin Y#. (2014) Rapid evolution of cellulosome modules by comparative analyses of five Clostridiales genomes. Bioenergy Research 7:1369–1381. doi
Yin Y#, Johns MA, Cao H^, Rupani M^. (2014) A survey of the genomes and transcriptomes of diverse plants and algae reveals new insights into the evolution and function of the cellulose synthase superfamily. BMC Genomics 15:260. doi Highly accessed · 34+ citations
Cao H^, Shimura Y, Masanobu K, Yin Y#. (2014) Draft genome sequence of the toxic bloom-forming cyanobacterium Aphanizomenon flos-aquae NIES-81. Genome Announc. 2(1):e00044-14. doi
Escamilla-Trevino L, Shen H, Hernandez T, Yin Y, Xu Y, and Dixon RA. (2014) Early lignin pathway enzymes and routes to chlorogenic acid in switchgrass (Panicum virgatum L.). Plant Mol Biol. 84(4-5):565–576. doi
Zhao Q, Nakashima Q, Chen F, Yin Y, Yun J, Shao H, Wang X, and Dixon RA. (2013) LACCASE is necessary and non-redundant with PEROXIDASE for lignin polymerization during vascular development in Arabidopsis thaliana. Plant Cell 25(10):3976–3987. doi ★ ESI Highly Cited (Top 1%) — Plant & Animal Science · Faculty 1000 Selection
Liu J, Duan X, Sun J, Yin Y, Li G, Wang L, Liu B. (2013) Bi-factor Analysis Based on Noise-reduction (BIFANR): A New Algorithm for Detecting Coevolving Amino Acid Sites in Proteins. PLoS ONE 8(11):e79764. doi
Ma Q, Liu B, Zhou C, Yin Y, Li G, Xu Y. (2013) An integrated toolkit for accurate prediction and analysis of cis-regulatory motifs at a genome scale. Bioinformatics 29(18):2261–2268.
Yin Y#. (2013) Databases for bioenergy-related enzymes. Chapter 6 of Bioenergy Research: Advances & Applications, Elsevier Publishing, edited by Gupta VJ et al., pp. 95–107.
Ma Q*, Yin Y*, Schell M, Li G, Xu Y. (2013) Elucidation of the Dynamic Supercoil Structures of folded E. coli Chromosome: a computational approach. Nucleic Acids Research 41(11):5594–5603.
Zhang JY, Lee YC, Torres-Jerez I, Wang M, Yin Y, Chou WC, He J, Shen H, Srivastava AC, Pennacchio C, Lindquist E, Grimwood J, Schmutz J, Xu Y, Sharma M, Sharma R, Bartley LE, Ronald PC, Saha MC, Dixon RA, Tang Y, Udvardi MK. (2013) Development of an integrated transcript sequence database and a gene expression atlas for gene discovery and analysis in switchgrass (Panicum virgatum L.). Plant J. 74(1):160–173. doi
Wang S*, Yin Y*, Ma Q, Tang X, Xu Y. (2012) Genome-scale identification of cell-wall related genes in Arabidopsis based on co-expression network analysis. BMC Plant Biology 12:138.
Li G, Köllner TG, Yin Y, Jiang Y, Xu Y, Gershenzon J, Pichersky E, Chen F. (2012) Nonseed plant Selaginella moellendorffii has both seed plant and microbial types of terpene synthases. PNAS 109(36):14711–14715. Faculty 1000 — Must Read
Blumer-Schuette SE, Giannone RJ, Zurawski JV, Ozdemir I, Mistry DB, Ma Q, Yin Y, Xu Y, Poole FL II, Kataeva I, Adams MWW, Hamilton-Brehm SD, Elkins JG, Larimer FW, Land ML, Hauser L, Cottingham RW, Hettich RL, and Kelly RM. (2012) Caldicellulosiruptor core and pan genomes reveal determinants for non-cellulosomal thermophilic deconstruction of lignocellulose. J Bacteriol. 194(15):4015–4028.
Mao X, Zhang H, Yin Y, Xu Y. (2012) The percentage of bacterial genes on leading versus lagging strands is influenced by multiple balancing forces. Nucleic Acids Res. 40(17):8210–8218.
Yin Y*, Mao X*, Yang JC, Chen X, Xu Y. (2012) dbCAN: a web resource for automated carbohydrate-active enzyme annotation. Nucleic Acids Res. (web server issue) 40:W445–W451. doi ★ ESI Highly Cited (Top 1%) — Biology & Biochemistry · DOE Key Advance for Biofuels Production · 832+ citations
Zhang H*, Yin Y*, Olman V, Xu Y. (2012) Genomic arrangement of regulons in bacterial genomes. PLoS One 7(1):e29496. PubMed PMCID: PMC3250446.
Kulkarni AR, Peña MJ, Avci U, Mazumder K, Urbanowicz BR, Pattathil S, Yin Y, O'Neill MA, Roberts AW, Hahn MG, Xu Y, Darvill AG, York WS. (2012) The ability of land plants to synthesize glucuronoxylans predates the evolution of tracheophytes. Glycobiology 22(3):439–451. PubMed PMID: 22048859.
Yin Y, Huang J, Gu X, Bar-Peled M, Xu Y. (2011) Evolution of plant nucleotide-sugar interconversion enzymes. PLoS One 6(11):e27995. PubMed PMCID: PMC3220709.
Yin Y, Mohnen D, Xu Y, Hahn M. (2011) Glycosyltransferase Family 8 (GT8). Book chapter of Plant Cell Wall Polysaccharides: Biosynthesis and Bioengineering. Annual Plant Review series (Blackwell) 41:167–212.
Li G, Ma Q, Mao X, Yin Y, Zhu X, Xu Y. (2011) Integration of sequence-similarity and functional association information can overcome intrinsic problems in orthology mapping across bacterial genomes. Nucleic Acids Res. 39(22):e150. PubMed PMCID: PMC3239196.
Kong Y, Zhou G, Yin Y, Xu Y, Pattathil S, Hahn MG. (2011) Molecular analysis of a family of Arabidopsis genes related to galacturonosyltransferases. Plant Physiol. 155(4):1791–1805. PubMed PMCID: PMC3091093.
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Yin Y, Chen H, Hahn MG, Mohnen D, Xu Y. (2010) Evolution and function of the plant cell wall synthesis-related glycosyltransferase family 8. Plant Physiol. 153(4):1729–1746. PubMed PMCID: PMC2923890.
Yin Y*, Zhang H*, Olman V, Xu Y. (2010) Genomic arrangement of bacterial operons is constrained by biological pathways encoded in the genome. PNAS 107(14):6310–6315. PubMed PMCID: PMC2851940.
Chou WC, Yin Y, Xu Y. (2010) GolgiP: prediction of Golgi-resident proteins in plants. Bioinformatics 26(19):2464–2465. PubMed PMCID: PMC2944200.
Zhou C, Yin Y, Dam P, Xu Y. (2010) Identification of novel proteins involved in plant cell-wall synthesis based on protein-protein interaction data. J Proteome Res. 9(10):5025–5037.
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Gu X, Glushka J, Yin Y, Xu Y, Denny T, Smith J, Jiang Y, Bar-Peled M. (2010) Identification of a bifunctional UDP-4-keto-pentose/UDP-xylose synthase in the plant pathogenic bacterium Ralstonia solanacearum strain GMI1000. J Biol Chem. 285(12):9030–9040. PubMed PMCID: PMC2838324.
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Shen H*, Yin Y*, Chen F, Xu Y, Dixon R. (2009) A bioinformatic analysis of NAC genes for plant cell wall development in relation to lignocellulosic bioenergy production. Bioenergy Research 2(4):217–232.
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Yin Y, Fischer D. (2008) Identification and investigation of ORFans in the viral world. BMC Genomics 9:24. PubMed PMCID: PMC2245933.
Huang ML, Sun DC, Lou YX, Yin Y, Li CY, Zhang Y, Gao G, Wang SQ, Bo XC, Wei LP, Li SG. (2008) Analysis and Preparation of Oligonucleotide Microarray of Apoptosis related Genes. Prog. Biochem. Biophys. 35(12):1451–1460.
Yin Y, Fischer D. (2006) On the origin of microbial ORFans: quantifying the strength of the evidence for viral lateral transfer. BMC Evol Biol. 6:63. PubMed PMCID: PMC1559721.
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Huang M, Wang Y, Sun D, Zhu H, Yin Y, Zhang W, Yang S, Quan L, Bai J, Wang S, Chen Q, Li S, Xu N. (2006) Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis. BMC Cancer 6:221. PubMed PMCID: PMC1574340.
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* co-first authors | # corresponding authors | ^ UNL/NIU grad student/postdoc | + undergraduate student