dbAPIS: a database of anti-prokaryotic immune systems

Seed protein information help

APIS family ID

APIS035

Inhibited defense system

broad-spectrum counter-defense

CLAN ID

CLAN032

Seed protein property

Accession ID	Gene name	Protein length	Molecular weight	Isoelectric point	Charge
YP_009790938.1	gene_page: orf148	115	13375.95	4.0052	-12.0

Phage property

Phage	Assembly id
Escherichia phage OSYSP	GCF_002627205.1

PMID/References

Silas et al., 2023

PDB structures

;

Pfam domains

Phrog

phrog_3972,phrog_16544

Host taxa

d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Escherichia;

Gene Location

Start: 6432; End: 6779; Strand: -

Description

Broad-spectrum counter-defense.

Seed genomic context Download table help

Genome accession	Start	End	Strand	Protein ID	Length	Molecular weight	Charge	Isoelectric point	Function	Phrog
NC_047835.1	4114	4467	-	YP_009790933.1	117	13141.82	-8.0	4.2178	hypothetical protein	phrog_7572
NC_047835.1	4557	4700	-	YP_009790934.1	47	5481.57	-1.0	4.5440	hypothetical protein	phrog_13931
NC_047835.1	4700	5017	-	YP_009790935.1	105	12702.88	5.0	8.0941	hypothetical protein	phrog_6053
NC_047835.1	5115	5282	-	YP_009790936.1	55	6458.46	5.5	10.0624	hypothetical protein	phrog_6221
NC_047835.1	5469	5627	-	YP_009790937.1	52	5856.22	2.5	8.5537	hypothetical protein	phrog_18174
NC_047835.1	6432	6779	-	YP_009790938.1	115	13375.95	-12.0	4.0052	hypothetical protein	phrog_16544 ; phrog_3972
NC_047835.1	6892	7077	-	YP_009790939.1	61	7159.32	1.0	7.2032	hypothetical protein	phrog_5473
NC_047835.1	7332	7523	-	YP_009790940.1	63	7249.18	-1.0	5.6351	hypothetical protein	phrog_7042
NC_047835.1	7524	7742	-	YP_009790941.1	72	7920.04	-4.0	4.2850	hypothetical protein	phrog_8408
NC_047835.1	7793	8065	-	YP_009790942.1	90	10828.58	11.0	10.1441	hypothetical protein	phrog_5876
NC_047835.1	8543	8818	-	YP_009790943.1	91	10200.65	-10.0	3.9759	hypothetical protein	phrog_4991 ; phrog_4551

Seed genomic context- JBrowse

Predicted 3D structure by alphafold2 with pTM = 0.8 Download help

pTM is for the estimate of the TM-score, which is obtained from a pairwise error prediction. The higher pTM score indicates better model quality.

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence

90 < plddt <=100 ;

70 < plddt <= 90 ;

50 < plddt <= 70 ;

0 <= plddt <= 50 ; Download help

Structural homologs

No homologs found in AlphaFold database

Structure homologs against by esmdb (html) ; download full result table

Hit	Query start	Query end	Hit start	Hit end	TMscore(ali)	TMscore(avg)
MGYP000932118009.pdb	2	115	1	98	0.6662	0.63
MGYP003611076310.pdb	1	115	1	96	0.6362	0.5643

Family information Download help

Fam ID	Seed protein	Member count	Model	Alignment
APIS035	YP_009790938.1	111	HMM model	Member alignment

Host Taxa distribution

Length distribution

Homology to other families download full data without filtering help

Clan ID: CLAN032

Hit APIS family	E-Value	Query Start	Query End	Hit Start	Hit End	Immune system	Seed protein
APIS075	6.32E-55	1	97	26	129	-	KY083726_00051
APIS047	7.98E-54	1	98	21	124	-	IMGVR_UViG_3300009183_005911\|3300009183\|Ga0114974_10000105111
APIS050	5.86E-51	1	97	2	112	-	IMGVR_UViG_3300010885_038456\|3300010885\|Ga0133913_1000088583
APIS074	8.65E-49	1	97	5	105	-	IMGVR_UViG_3300042691_005779\|3300042691\|Ga0415385_0000706_88760_89182
APIS082	7.60E-22	1	91	2	98	-	MGV-GENOME-0365202_107

Family members, sources, and their hosts help

Results of representative protein blast against members.

Member	pident	evalue	bitscore	qcovs	phage	host	SourceDB	Phrog
AJ604530_00025	87.826	6.24e-69	210	100%	Escherichia phage Bf23	Escherichia	INPHARED	phrog_3972 phrog_16544
AJ604531_00024	87.826	1.22e-68	209	100%	Salmonella phage 5	Salmonella	INPHARED	phrog_3972 phrog_16544
AY543070_00080	90.435	8.36e-71	215	100%	Escherichia phage T5	Escherichia	INPHARED	phrog_3972 phrog_16544
HQ406778_00080	96.522	1.03e-74	225	100%	Salmonella phage Spc35	Salmonella	INPHARED	phrog_3972 phrog_16544
IMGVR_UViG_2974539709_000001\|2974539709\|2974539728	97.391	7.56e-76	228	100%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300002304_000059\|3300002304\|B570J29606_100000716	49.550	3.60e-29	110	91%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300002835_001195\|3300002835\|B570J40625_10000610431	40.594	8.56e-18	80.9	88%			IMGVR	phrog_3972
IMGVR_UViG_3300005527_000314\|3300005527\|Ga0068876_1000096043	42.056	2.10e-19	85.1	88%			IMGVR	phrog_3972
IMGVR_UViG_3300007735_000795\|3300007735\|Ga0104988_1101653	46.226	9.60e-21	89.0	88%			IMGVR	phrog_3972
IMGVR_UViG_3300007987_000422\|3300007987\|Ga0100379_1000484216	44.444	2.46e-20	87.0	86%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300008111_000162\|3300008111\|Ga0114344_10005858	42.857	1.99e-19	85.5	89%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300008117_001051\|3300008117\|Ga0114351_100547430	44.643	1.07e-20	89.0	89%			IMGVR	phrog_3972
IMGVR_UViG_3300008996_000193\|3300008996\|Ga0102831_10018175	55.102	6.29e-28	106	83%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300009158_000035\|3300009158\|Ga0114977_10000009158	48.649	4.43e-28	107	93%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300009158_000443\|3300009158\|Ga0114977_100019227	45.098	1.27e-20	88.2	88%			IMGVR	phrog_3972
IMGVR_UViG_3300009701_000001\|3300009701\|Ga0116228_1000003366	49.515	3.33e-23	95.1	85%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300013093_000181\|3300013093\|Ga0164296_100104533	49.515	4.03e-21	89.4	86%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300014204_000328\|3300014204\|Ga0172381_100006729	57.000	1.26e-30	113	87%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300016484_000277\|3300016484\|Ga0186813_1154323	41.964	8.41e-18	81.3	86%			IMGVR	phrog_3972
IMGVR_UViG_3300020045_002765\|3300020045\|Ga0206662_100060555	51.923	4.22e-25	99.8	86%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300020045_005021\|3300020045\|Ga0206662_100011268	53.846	1.46e-29	110	87%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300020112_000574\|3300020112\|Ga0207380_129540663	48.113	5.13e-24	97.1	85%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300020513_000003\|3300020513\|Ga0208090_1000002174	49.550	3.49e-29	110	91%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300020562_000034\|3300020562\|Ga0208597_10004169	40.594	8.34e-18	80.9	88%			IMGVR	phrog_3972
IMGVR_UViG_3300020576_002235\|3300020576\|Ga0212216_1000005555	52.041	2.01e-23	95.1	85%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300021474_000004\|3300021474\|Ga0210390_1000015643	54.902	1.39e-27	105	86%		Firmicutes_A	IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300023301_002443\|3300023301\|Ga0209414_100083015	49.038	7.10e-26	101	90%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300025276_000077\|3300025276\|Ga0208814_100023648	50.000	2.34e-24	97.4	84%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300027418_000620\|3300027418\|Ga0208022_10023695	55.102	6.11e-28	106	83%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300027733_000001\|3300027733\|Ga0209297_100001758	48.649	4.30e-28	107	93%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300027808_002635\|3300027808\|Ga0209354_100029816	47.525	1.55e-22	92.8	85%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300031787_000064\|3300031787\|Ga0315900_1000037940	45.872	5.57e-21	89.4	86%			IMGVR	phrog_3972
IMGVR_UViG_3300032038_000041\|3300032038\|Ga0326512_10000058106	50.000	6.62e-23	94.0	86%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300032116_016515\|3300032116\|Ga0315903_1001040920	55.882	1.02e-31	116	86%		Pseudanabaena	IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300032288_002343\|3300032288\|Ga0335290_169808617	40.594	4.70e-18	81.6	84%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300032431_000003\|3300032431\|Ga0335395_100000562	45.545	1.84e-22	92.8	86%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300034167_000773\|3300034167\|Ga0335017_0000041_3979_4329	47.000	4.48e-18	82.0	86%			IMGVR	phrog_3972
IMGVR_UViG_3300034280_000588\|3300034280\|Ga0334997_0000011_116409_116765	48.113	8.23e-23	94.0	83%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300035041_000007\|3300035041\|Ga0376515_000006_63811_64125	53.398	2.61e-29	110	85%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300035104_000006\|3300035104\|Ga0376528_00009_12319_12633	54.369	3.92e-29	109	85%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300035661_000043\|3300035661\|Ga0373633_0000254_59439_59759	50.000	5.39e-26	101	87%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300036466_000273\|3300036466\|Ga0377201_000021_14410_14706	54.082	1.38e-28	108	85%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300037300_000098\|3300037300\|Ga0400271_008807_765_1079	54.369	6.13e-29	109	87%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300037502_001745\|3300037502\|Ga0310151_0000455_3610_3915	46.000	2.39e-21	89.7	83%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300042288_001742\|3300042288\|Ga0453147_0013835_386_676	42.157	6.35e-18	80.9	89%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300042292_000666\|3300042292\|Ga0453156_0000064_34002_34406	39.844	1.18e-22	94.4	100%			IMGVR	phrog_3972
IMGVR_UViG_3300042351_001004\|3300042351\|Ga0453931_0000047_9421_9711	44.444	4.60e-19	84.0	86%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300042434_001247\|3300042434\|Ga0453894_0021561_1295_1585	42.157	9.51e-18	80.5	89%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300042450_002071\|3300042450\|Ga0453063_0004356_8829_9125	40.594	3.76e-18	81.6	88%			IMGVR	phrog_3972
IMGVR_UViG_3300042465_004089\|3300042465\|Ga0453065_0000365_15783_16100	52.041	9.87e-26	101	83%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300042549_002773\|3300042549\|Ga0454392_0001006_12283_12597	49.000	1.57e-25	100	85%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300042908_000425\|3300042908\|Ga0453089_0001881_14854_15189	48.649	1.37e-28	108	91%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300043425_000660\|3300043425\|Ga0451744_0000078_974_1300	45.631	1.97e-18	82.8	84%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300044612_001914\|3300044612\|Ga0453747_0000542_8185_8475	42.157	4.48e-18	81.3	89%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300044956_000607\|3300044956\|Ga0438282_001670_17095_17466	45.098	2.36e-19	85.5	83%			IMGVR	phrog_3972
IMGVR_UViG_3300045587_000364\|3300045587\|Ga0466451_000632_5093_5500	42.574	7.62e-20	87.0	85%			IMGVR	phrog_3972
IMGVR_UViG_3300045743_000147\|3300045743\|Ga0485836_0000236_15022_15336	48.039	1.66e-25	100	87%			IMGVR	phrog_3972
IMGVR_UViG_3300045988_012343\|3300045988\|Ga0495776_020668_509_829	44.860	5.40e-22	91.7	89%		Escherichia	IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300046004_001066\|3300046004\|Ga0485179_000522_16028_16336	43.000	9.06e-20	85.9	84%			IMGVR	phrog_3972
IMGVR_UViG_3300048672_000535\|3300048672\|Ga0485282_000142_3828_4172	51.000	7.30e-26	101	84%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300049199_000005\|3300049199\|Ga0498785_000005_2555_2872	54.286	1.67e-28	108	88%			IMGVR	phrog_3972 phrog_16544
IMGVR_UViG_3300049489_000253\|3300049489\|Ga0499958_0001069_9562_9873	48.980	2.94e-24	97.4	83%			IMGVR	phrog_3972
KJ190157_00079	86.957	1.44e-67	207	100%	Escherichia phage vB_EcoS_FFH_1	Escherichia	INPHARED	phrog_3972 phrog_16544
KM979354_00065	87.826	4.16e-69	211	100%	Escherichia phage DT57C	Escherichia	INPHARED	phrog_3972 phrog_16544
KM979355_00061	87.826	5.24e-69	211	100%	Escherichia phage DT571/2	Escherichia	INPHARED	phrog_3972 phrog_16544
KP143763_00067	87.826	2.52e-68	209	100%	Salmonella phage Shivani	Salmonella	INPHARED	phrog_3972 phrog_16544
KY963424_00167	95.652	1.45e-74	224	100%	Shigella phage SSP1	Shigella	INPHARED	phrog_3972 phrog_16544
LN887948_00147	98.261	1.25e-76	230	100%	Escherichia phage slur09	Escherichia	INPHARED	phrog_3972 phrog_16544
LR597655_00080	88.696	8.46e-70	213	100%	Escherichia phage T5_ev219	Escherichia	INPHARED	phrog_3972 phrog_16544
MF774688_00039	95.652	4.94e-75	226	100%	Salmonella phage SP1a	Salmonella	INPHARED	phrog_3972 phrog_16544
MG387042_00072	92.174	6.40e-72	218	100%	Salmonella phage SP3	Salmonella	INPHARED	phrog_3972 phrog_16544
MGV-GENOME-0288342_2	44.860	5.55e-22	91.7	89%		Escherichia	MGV	phrog_3972 phrog_16544
MGV-GENOME-0370602_58	86.957	1.44e-68	209	100%			MGV	phrog_3972 phrog_16544
MH203051_00062	86.957	6.68e-68	207	100%	Escherichia phage Gostya9	Escherichia	INPHARED	phrog_3972 phrog_16544
MK373792_00069	90.435	5.88e-71	215	100%	Escherichia phage vB_EcoS_VAH1	Escherichia	INPHARED	phrog_3972 phrog_16544
MK373796_00078	86.957	2.93e-68	209	100%	Escherichia phage vB_EcoS_HdH2	Escherichia	INPHARED	phrog_3972 phrog_16544
MK972716_00020	95.652	1.02e-74	225	100%	Salmonella phage SE8	Salmonella	INPHARED	phrog_3972 phrog_16544
MN022787_00081	88.696	9.75e-70	213	100%	Salmonella phage VSe12	Salmonella	INPHARED	phrog_3972 phrog_16544
MN070121_00010	47.115	2.05e-21	90.1	86%	Salmonella phage Shemara	Salmonella	INPHARED	phrog_3972 phrog_16544
MN316588_00084	88.696	1.75e-69	212	100%	Escherichia phage VEc33	Escherichia	INPHARED	phrog_3972 phrog_16544
MN445182_00071	94.783	2.16e-73	221	100%	Salmonella phage vB_SalS_SA001	Salmonella	INPHARED	phrog_3972 phrog_16544
MN956514_00079	95.652	7.33e-75	225	100%	Salmonella phage L6jm	Salmonella	INPHARED	phrog_3972 phrog_16544
MN970211_00078	87.826	1.05e-68	210	100%	Phage NBEco001		INPHARED	phrog_3972 phrog_16544
MN994496_00077	87.826	2.43e-68	209	100%	Phage NBEco002		INPHARED	phrog_3972 phrog_16544
MN994502_00117	95.652	3.85e-74	223	100%	Phage NBSal003		INPHARED	phrog_3972 phrog_16544
MN994504_00122	96.522	1.18e-74	225	100%	Phage NBSal005		INPHARED	phrog_3972 phrog_16544
MT074448_00116	96.522	5.27e-75	226	100%	Salmonella phage oldekolle	Salmonella	INPHARED	phrog_3972 phrog_16544
MT080103_00107	97.030	1.42e-65	201	88%	Escherichia phage ECOP18	Escherichia	INPHARED	phrog_3972 phrog_16544
MT233524_00146	91.304	9.10e-72	218	100%	Salmonella phage vB_Sen_I1	Salmonella	INPHARED	phrog_3972 phrog_16544
MT311645_00032	96.522	2.92e-75	226	100%	Salmonella phage vB_Sen-E22	Salmonella	INPHARED	phrog_3972 phrog_16544
MT577844_00096	87.826	8.30e-69	210	100%	Salmonella phage vB_StyS-LmqsSP1	Salmonella	INPHARED	phrog_3972 phrog_16544
MW006481_00080	90.435	7.57e-71	215	100%	Salmonella phage GEC_vB_N7	Salmonella	INPHARED	phrog_3972 phrog_16544
MZ398246_00066	88.696	3.89e-69	211	100%	Escherichia phage IME178	Escherichia	INPHARED	phrog_3972 phrog_16544
MZ501058_00100	91.304	2.95e-71	216	100%	Escherichia phage DaisyDussoix	Escherichia	INPHARED	phrog_3972 phrog_16544
MZ501074_00101	97.391	7.07e-76	228	100%	Escherichia phage HildyBeyeler	Escherichia	INPHARED	phrog_3972 phrog_16544
OK143207_00095	97.391	2.91e-76	229	100%	Escherichia phage Lindwurm	Escherichia	INPHARED	phrog_3972 phrog_16544
OK254197_00094	97.391	1.68e-75	227	100%	Escherichia phage PNJ1902	Escherichia	INPHARED	phrog_3972 phrog_16544
OL800604_00095	97.391	1.59e-75	227	100%	Salmonella phage vB_STy-RN29	Salmonella	INPHARED	phrog_3972 phrog_16544
OM386660_00057	89.565	3.44e-70	213	100%	Escherichia phage vB_EcoS_ESCO40	Escherichia	INPHARED	phrog_3972 phrog_16544
ON185584_00089	96.522	1.29e-75	227	100%	Escherichia phage EC142	Escherichia	INPHARED	phrog_3972 phrog_16544
ON185585_00078	95.652	3.16e-74	224	100%	Escherichia phage EC148	Escherichia	INPHARED	phrog_3972 phrog_16544
OP394141_00126	98.261	7.62e-77	230	100%	Salmonella phage GSP044	Salmonella	INPHARED	phrog_3972 phrog_16544
OQ031075_00121	95.652	3.76e-74	223	100%	Klebsiella phage KPP2018	Klebsiella	INPHARED	phrog_3972 phrog_16544
OQ359888_00085	89.565	2.29e-70	214	100%	Salmonella phage vB_SenS_UTK0008	Salmonella	INPHARED	phrog_3972 phrog_16544
OQ383620_00096	88.696	3.45e-69	211	100%	Salmonella phage MET_P1_100_107	Salmonella	INPHARED	phrog_3972 phrog_16544
OQ680480_00075	96.522	7.83e-75	225	100%	Salmonella phage phC11	Salmonella	INPHARED	phrog_3972 phrog_16544
OQ680481_00076	94.783	4.90e-74	223	100%	Salmonella phage phC17	Salmonella	INPHARED	phrog_3972 phrog_16544
uvig_307076_76	88.696	1.14e-69	212	100%			GPD	phrog_3972 phrog_16544
uvig_424435_36	86.957	1.39e-68	209	100%			GPD	phrog_3972 phrog_16544
uvig_586390_23	42.202	4.23e-19	84.3	89%			GPD	phrog_3972 phrog_16544
YP_009790938.1	100.000	1.42e-84	233	100%	Escherichia phage OSYSP	Escherichia	NCBI	phrog_3972 phrog_16544

APIS	Contig	Range
APIS035	NC_047835.1	4114 - 8818