Browse anti-prokaryotic immune system families by Defense system

AD families AD genes Defense system CLAN ID Phages/MGEs References Description
APIS005 Gad1 Gabija CLAN009 phi3T of B. subtilis Yirmiya et al., 2023 Antine et al., 2023 Gad1 forms an octameric web that encases the GajAB complex and inhibits DNA recognition and cleavage.
APIS008 Gad2 Gabija CLAN023 SPbetaL7 of B. subtilis Yirmiya et al., 2023 Alphafold2 predicted that Gad2 is an enzyme with a nucleotidyltransferase protein domain, suggesting that it inhibits Gabija via a mechanism of action different than Gad1.
APIS046 CLAN009
APIS053 CLAN009
APIS056 CLAN023
APIS057 CLAN009
APIS059 CLAN023 Pseudoalteromonas phage HM1
APIS065 CLAN009 Shewanella sp. phage 1/4
APIS068 CLAN009
APIS071 CLAN009
APIS083 CLAN009 Clostridioides phage ES-S-0107-01
APIS088 CLAN009
APIS089 CLAN023