y
Basic Information | |
---|---|
Species | Phaseolus vulgaris |
Cazyme ID | Phvul.002G226400.1 |
Family | GT4 |
Protein Properties | Length: 422 Molecular Weight: 47212.9 Isoelectric Point: 7.1181 |
Chromosome | Chromosome/Scaffold: 02 Start: 39128905 End: 39135529 |
Description | UDP-Glycosyltransferase superfamily protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT4 | 179 | 317 | 6.6e-34 |
EIVIVIISRLVYRKGADLLVEVIPEVCRLHPNVRFIIGGDGPKRVRLEEMREKHSLFDRVDLLGAVPHTQVRSVLISGHIFLTCSLTEAFCMAILEAASC GLLTVSTRVGGVPEVLPDDMVVLAEPDPGDIVQAIQTAI |
Full Sequence |
---|
Protein Sequence Length: 422 Download |
MMGDSPPQKH RVLMASDFYY PNFGGVENHV YYLSQCLLKL GHKVVVVTHA YGKRSGVRYM 60 TGGLKVYYVP WRQFFNQIHG HQTFSTLCHD ALLNARIMGY KVVFTDHSLH GFGDVGSIHM 120 NKVMQFTLAD VSQAICVSHT SKENTVLRSG LAPEKVFVIP NAVDTAMFKP ALDRPSGSEI 180 VIVIISRLVY RKGADLLVEV IPEVCRLHPN VRFIIGGDGP KRVRLEEMRE KHSLFDRVDL 240 LGAVPHTQVR SVLISGHIFL TCSLTEAFCM AILEAASCGL LTVSTRVGGV PEVLPDDMVV 300 LAEPDPGDIV QAIQTAISML PKIDPQVMHN RLRELYNWHD VAKRTEIVYD RALKCPNQSL 360 LECLSRYLSC GALAGKLFCL VMILSFLFWH LLELWQPADD IEEVPDVIFS KNCDEDFSQK 420 S* 480 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR00032 | argG | 1.0e-36 | 11 | 352 | 384 | + argininosuccinate synthase. argG in bacteria, ARG1 in Saccharomyces cerevisiae. There is a very unusual clustering in the alignment, with a deep split between one cohort of E. coli, H. influenzae, and Streptomyces, and the other cohort of eukaryotes, archaea, and the rest of the eubacteria [Amino acid biosynthesis, Glutamate family]. | ||
COG0438 | RfaG | 5.0e-41 | 11 | 354 | 380 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
cd03798 | GT1_wlbH_like | 2.0e-54 | 12 | 352 | 379 | + This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS. | ||
cd03801 | GT1_YqgM_like | 3.0e-68 | 11 | 349 | 380 | + This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. | ||
cd03796 | GT1_PIG-A_like | 0 | 11 | 382 | 398 | + This family is most closely related to the GT1 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0006506 | GPI anchor biosynthetic process |
GO:0009058 | biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAH01229.1 | 0 | 4 | 407 | 23 | 450 | unnamed protein product [Oryza sativa Japonica Group] |
RefSeq | NP_566874.1 | 0 | 7 | 407 | 4 | 428 | SETH2; transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002279568.1 | 0 | 2 | 406 | 1 | 427 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002461824.1 | 0 | 4 | 407 | 2 | 429 | hypothetical protein SORBIDRAFT_02g008800 [Sorghum bicolor] |
RefSeq | XP_002529442.1 | 0 | 8 | 421 | 4 | 441 | glycosyltransferase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2jjm_L | 0.00000007 | 65 | 334 | 90 | 363 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
PDB | 2jjm_K | 0.00000007 | 65 | 334 | 90 | 363 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
PDB | 2jjm_J | 0.00000007 | 65 | 334 | 90 | 363 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
PDB | 2jjm_I | 0.00000007 | 65 | 334 | 90 | 363 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
PDB | 2jjm_H | 0.00000007 | 65 | 334 | 90 | 363 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
EE592228 | 224 | 4 | 203 | 0 |
EE592228 | 212 | 196 | 407 | 0 |
GO854391 | 315 | 93 | 407 | 0 |
DN795468 | 262 | 89 | 350 | 0 |
DY295948 | 306 | 8 | 289 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|