Seed protein information help

APIS family ID APIS245
Inhibited defense system Thoeris
CLAN ID CLAN001
Seed protein property
Accession ID Gene name Protein length Molecular weight Isoelectric point Charge
Ga0495776_136213_37340_37531
gene_page: SequestinM 63 7316.39 5.018 -1
Phage property
Phage Assembly id
IMGVR_UViG_3300045988_171361
PMID/References PMID:41785351
PDB structures ;
Pfam domains PF21825
Phrog phrog_4211,phrog_4120,phrog_2598,phrog_2120,phrog_10871
Host taxa d__Bacteria;p__Bacteroidota;c__Bacteroidia;o__Bacteroidales;f__Bacteroidaceae;g__Bacteroides;
Gene Location Start: 37340;  End: 37531;  Strand: -
Description Sequestin-family anti-defense protein; inhibits type I Thoeris signaling, most likely by binding 3′cADPR.

Seed genomic context      Download table help

Genome accession Start End Strand Protein ID Length Molecular weight Charge Isoelectric point Function Phrog PFAM

Seed genomic context- JBrowse     

Predicted 3D structure by alphafold2 with pTM = 0.79 Download help

pTM is for the estimate of the TM-score, which is obtained from a pairwise error prediction. The higher pTM score indicates better model quality.

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence
90 < plddt <=100 ;
70 < plddt <= 90 ;
50 < plddt <= 70 ;
0 <= plddt <= 50 ;      Download help

Structural homologs

No homologs found in AlphaFold database

No homologs found in esmfold database

Family information      Download help

Fam ID Seed protein Member count Model Alignment
APIS245 Ga0495776_136213_37340_37531 58 HMM model Member alignment

Host Taxa distribution

Length distribution

Length Distribution Bar chart

Homology to other families       help

Clan ID: CLAN001

APIS245 has no similar APIS family.

Family members, sources, and their hosts        help

Results of representative protein blast against members.

Member pident evalue bitscore qcovs phage host SourceDB Pfam Phrog
IMGVR_UViG_3300009692_000135|3300009692|Ga0116171_1000288530 72.800 3.973E-24 91 0.952% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300001605_002657|3300001605|Draft_100186242 78.100 2.121E-28 103 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
Ga0495776_136213_37340_37531 100.000 1.466E-35 124 1.000% Bacteroides NCBI PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_166377_4 64.200 3.132E-21 83 1.000% GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0343007_34 88.600 9.025E-34 119 1.000% Bacteroides MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_219841_13 61.800 5.469E-20 79 1.000% GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300007804_000066|3300007804|Ga0105665_10094018 92.000 1.466E-35 124 1.000% Bacteroidaceae IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_8613_1 88.600 9.025E-34 119 1.000% Bacteroides faecis GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300020576_002256|3300020576|Ga0212216_100014456 74.900 9.550E-27 98 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0340414_11 64.000 4.303E-21 82 1.000% MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300002220_000240|3300002220|MLSBCLC_1000939485 64.200 3.132E-21 83 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_55613_58 64.000 4.303E-21 82 1.000% GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300016478_000321|3300016478|Ga0186807_1390067 70.100 2.893E-24 91 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300023198_000563|3300023198|Ga0255983_10471613 48.800 3.231E-13 60 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0358222_51 85.600 2.951E-32 114 1.000% Bacteroides MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_108604_60 65.600 6.396E-22 85 1.000% GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_151801_36 64.000 4.303E-21 82 1.000% GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0365847_52 65.600 6.396E-22 85 1.000% MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0366257_77 61.800 5.469E-20 79 1.000% MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0241876_27 81.300 4.714E-30 108 1.000% Parabacteroides MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_255217_47 89.100 4.788E-34 119 1.000% GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300037246_000876|3300037246|Ga0392329_0000047_40442_40633 81.900 2.500E-30 109 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
ivig_1007_15 85.600 2.951E-32 114 1.000% Bacteroides sp2 GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0348812_29 82.100 1.820E-30 109 1.000% Parabacteroides MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300045988_144353|3300045988|Ga0495776_180369_46193_46384 82.100 1.820E-30 109 1.000% Parabacteroides IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0277935_20 85.600 2.951E-32 114 1.000% Bacteroides MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300010352_000158|3300010352|Ga0116247_100102206 81.600 3.433E-30 108 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_7000000252_000007|7000000252|C2205952__gene_214763 81.300 4.714E-30 108 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_199166_51 85.600 2.951E-32 114 1.000% Bacteroides oleiciplenus GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300010352_002631|3300010352|Ga0116247_100252349 76.300 1.954E-27 100 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300006499_000321|3300006499|Ga0100371_1001312 73.100 8.806E-26 96 1.000% Parabacteroides IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_271223_38 87.700 2.336E-33 117 1.000% GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300000276_000160|3300000276|EM166_1005439125 78.900 8.187E-29 104 1.000% Parabacteroides IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300008547_000310|3300008547|Ga0111055_10003995 86.700 8.302E-33 116 1.000% Bacteroides IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
uvig_134562_11 72.000 3.135E-25 94 1.000% GPD PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300002175_000009|3300002175|JGI20166J26741_100555602 63.400 8.124E-21 81 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300020045_005654|3300020045|Ga0206662_100160911 73.300 6.411E-26 96 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300034059_000003|3300034059|Ga0374060_026961_76_237 64.900 1.128E-16 70 0.825% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300029374_000350|3300029374|Ga0243945_100050052 72.500 2.108E-20 80 0.841% Tannerellaceae IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300027984_000029|3300027984|Ga0209629_100009112 63.400 8.124E-21 81 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300029707_000319|3300029707|Ga0245244_100055178 73.100 8.806E-26 96 1.000% Parabacteroides IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300000276_000094|3300000276|EM166_10011167 72.000 3.135E-25 94 1.000% Bacteroidales IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300000062_000003|3300000062|IMNBL1DRAFT_0000051110 52.000 7.069E-15 64 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300037067_004317|3300037067|Ga0378408_0001110_17924_18109 64.800 1.659E-21 83 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300025575_000290|3300025575|Ga0209430_1000034160 61.300 1.033E-19 78 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300001868_000225|3300001868|JGI24146J20443_100010698 61.300 1.033E-19 78 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0363077_51 63.200 1.116E-20 81 1.000% MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
MGV-GENOME-0357025_36 64.000 4.303E-21 82 1.000% MGV PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300008096_000175|3300008096|Ga0114155_10086992 64.200 3.132E-21 83 1.000% Firmicutes IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300045988_017126|3300045988|Ga0495776_057084_44692_44883 63.200 1.116E-20 81 1.000% Firmicutes IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300000563_000195|3300000563|SL_3KL_010_SEDDRAFT_100149197 50.600 3.474E-14 63 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300044766_000022|3300044766|Ga0455974_0000009_29864_30082 52.600 3.474E-14 63 0.952% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300012145_000253|3300012145|Ga0136566_10036026 53.800 7.614E-16 67 1.000% Flavobacteriaceae IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300020049_002963|3300020049|Ga0206652_100838811 51.700 9.720E-15 64 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300028374_000701|3300028374|Ga0306906_10038764 53.800 7.614E-16 67 1.000% Flavobacteriaceae IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300037067_007420|3300037067|Ga0378408_0005349_16174_16368 53.300 1.439E-15 66 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300028920_000363|3300028920|Ga0272441_100084938 54.100 5.538E-16 68 1.000% IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871
IMGVR_UViG_3300033070_000214|3300033070|Ga0364486_105104 % IMGVR PF21825 phrog_4211 phrog_4120 phrog_2598 phrog_2120 phrog_10871