CAZyme Information: evm.model.AC2VRR_s00232g192-p1

Basic Information

• Species: Albugo candida
• Lineage: Oomycota; NA; ; Albuginaceae; Albugo; Albugo candida
• CAZyme ID: evm.model.AC2VRR_s00232g192-p1
• CAZy Family: GT48
• CAZyme Description: unspecified product

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1594	Acan2VRR_SC232|CGC1	181149.02	5.1771

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_Acandida2VRR	15896	911350	72	15824

• Gene Location: location=Acan2VRR_SC232:337710-342546(-)

Full Sequence      

MFPTKMHEEIKDTNTEVVLDVSGDAESSVTYPLRSWQELTDEVQSTIETIASEAMKLADT
LLPSHHNIMKLALLTRSYSPKVEMFRQMALDSMYHAPCEIHISSWAILTSPTCVLAYACS
KTQLEALVQDLHENSSSCVSPARNDKVFPVDHVFVGSKEENAASQNLTFILYGTIATSLF
YDLHKTIKPFAEIGRFTYIVRHYNRDSLLPTLLQGYGVSLDIKNMEYKAIDDDETDKFDE
NHGVSGMEDLEGLLFEKLVQHNEALKEGLEQFQETMLKKQVEDIIHEEEQLETWNLDNLG
MVAAFEILQSKDPLRHIKTLSQDFPKHAKRLAMAKNSLPPEIREILQQWRSSVVNHDYLD
TLVVNGIPISATRGSLNIFDLMQLIQQEWSLVKKFSNIGLPEHDIVQLREIGMESLKEAQ
YGTEKVVRIMIRGPLDGITPFYLNNIETNPAFARLPSSINTLKSPAWNLIQIRRNMYEVT
VIFDPTTQSGVAVLQEMQFLLVRGAPIQFSILPTSKELMNTVNLQERTKLIQSWKQASLG
EAATALHFSKIVLLIRDQALQDDADDNGDSLISQFLTLIPTLDVGYTISKLIGIFLETID
NEAETTEKVYAVLKSSRFDEEFISMSEFVLRKHLPFECYLFNGIIQSGLSIQEKLMENFG
RDQQIYQTLARADDLSDKRDLIEQLLESQDTFNSYFTIYSDSTSEVDFQSFIFEPKPALS
LLNNDLDGALERMLLHHVSYFHPIDSASIPKKETLIFLVSVQSPKACAHAYHGVAELLRT
NPKNSSNVRVGIVHLQEASPSGLDEDRKNVAQLILDIMSKAGTSDKRIVLEILAQALKCQ
MDGKTYEESKQILLELLAAHEPNLAAEWKEFVKAHITFPELQVDPNIQQLSGLMISSSGQ
CGHGTMTKLTPSTSHLFLNGRCVDLSEYVLGDSDIEDLLAYDLKSRTEDAAKVVLKDEVS
EMSVEEASLQSLYLMKVCGLLDQHRRWDRYNALELVTLPGSKDHPMIHIDGDSTLNVVAF
LDPLTEATQRMSSILQTLHTQLNATIDVILVPGSEYSEFPLRRFYKYVFGSAPLRVGNSI
MIGAAFRNLSIKPILTMNIDTVEEWNVHTYESRYDADNLLVDPQNEAEVRGTKTVSFILK
NLLVYGRCVDITDGRMIPPNGLQLVLDQRLGSETLSHDTLVMRNLGYFQLQAIPGVWSLH
LARGRAANLYEIVMNHGDSNAETEAVHSIPIFICDFNTRQTNLVVKKRPGKELIALLDSD
EYDKADHVEEDMNEAGHTRSFLNSYWTSVSSLLARRKSAAPISTDKAMEDSKDTIHVFSL
ATGHLYERFLKIMMLSVVKRTKSDVVFWLLENFLSPNFKRSIPALQAEFGIKIRLITYKW
PKWLRRQTVKQRIIWGYKILFLDVLFPLNVNRIVYVDADQVVRADLKELWEMDLKGAVYA
YAPFCGSRNLGFQFWREGFWKSHLQGKPYHISALYLVDLKQFRKIAAGDTLRGIYEQLSS
DPNSLANLDQDLPNFVQHNIPIFTLPQEWLWCESWCSDETKAEAKTIDLCNNPKEKEPKL
DMAKRVISGHLFQESWIELDQEIREGEKRSLARM

Enzyme Prediction     

EC	2.4.1.-:29

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT24	1315	1560	3.6e-121	0.9959677419354839

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
408203	Glyco_transf_24	1.63e-180	1315	1585	1	267	Glucosyltransferase 24. This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
133054	GT8_HUGT1_C_like	2.26e-155	1315	1560	1	248	The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
132996	Glyco_transf_8	2.96e-57	1315	1555	1	243	Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+.
408199	Thioredoxin_12	1.35e-23	38	203	31	177	Thioredoxin-like domain. This is one of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
399437	UDP-g_GGTase	3.13e-23	1146	1258	2	109	UDP-glucose:Glycoprotein Glucosyltransferase. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CCA14500.1|GT24	0.0	1	1592	81	1667
UIZ20865.1|GT24	0.0	41	1592	74	1662
AIG56125.1|GT24	0.0	52	1592	83	1507
AIG55512.1|GT24	0.0	54	1588	83	1513
CAB4116261.1|GT24	4.08e-196	67	1584	106	1553

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MU1_A	6.08e-141	63	1589	77	1450	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5MZO_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TRF_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TRT_A	1.57e-140	170	1589	164	1450	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5NV4_A	4.05e-140	63	1589	77	1450	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS2_A	1.22e-129	1013	1589	654	1216	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_C Chain C, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_D Chain D, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS8_A	3.87e-113	63	1522	70	1382	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS8_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q0WL80|UGGG_ARATH	1.51e-184	56	1585	91	1567	UDP-glucose:glycoprotein glucosyltransferase OS=Arabidopsis thaliana OX=3702 GN=UGGT PE=1 SV=1
sp|Q6P5E4|UGGG1_MOUSE	2.90e-178	61	1585	110	1522	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Uggt1 PE=1 SV=4
sp|Q9NYU2|UGGG1_HUMAN	4.36e-178	61	1585	110	1522	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3
sp|Q9JLA3|UGGG1_RAT	5.57e-178	61	1585	110	1522	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Uggt1 PE=1 SV=2
sp|Q9NYU1|UGGG2_HUMAN	1.35e-174	40	1585	80	1497	UDP-glucose:glycoprotein glucosyltransferase 2 OS=Homo sapiens OX=9606 GN=UGGT2 PE=1 SV=4

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000068	0.000000

TMHMM  Annotations     

There is no transmembrane helices in evm.model.AC2VRR_s00232g192-p1.