CAZyme Information: Z517_06369-t43_1-p1

Basic Information

• Species: Fonsecaea pedrosoi
• Lineage: Ascomycota; Eurotiomycetes; ; Herpotrichiellaceae; Fonsecaea; Fonsecaea pedrosoi
• CAZyme ID: Z517_06369-t43_1-p1
• CAZy Family: GH3
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
578	KN846972|CGC1	64609.60	6.8149

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_FpedrosoiCBS271-37	12573	1442368	46	12527

• Gene Location: location=KN846972:1592130-1594171(+)

Full Sequence      

MTSKLPVNTYADPEYDRAHQKTFAPPKIAPIKPVLPPNVTRADFETALHDLVAIVGQTQV
FIGDALAHYIDPYELYENDESKRKMPSAAVCPESTGELSQVLQVAKKFNIPLWTFSRGKN
LGYGGPAPRLNGSVALDLHRMNRVLEVNDEQGYAVVEPGVTFQDLYNYCIEHGKKVWPSI
PSLGWGSIIGNTLDRGVGYGAYANHHQYTAGLEVMLGDGDLVRTGQWGITNSPTAFVSKF
SYGPSVEGLFLQSNLGVVTKLSMWVAPRPPAFMSCSFSVPEDDDIEALVDALAEMRRTSL
IPNMIWVQNFGEILCIRGKRNTFWKGEGAIPKWRLKELQRELKVGSWVARWGLYGPERVL
RAQLAEIKEQLSRKAPTGTMEGFLYTEENGKPLDAKSIPPEHGLMLAGVPSLFSLPLMDW
PLGESGKAAHGDYAPVLPSTGKHIQGWVRACQDIYAAADLDFMVDFFMHERHSVCTSMYA
YDQLSSEQCKNVEKAYNEMHKVAKDKGYGMYRGHVNHMDEIADLNEFNNHAYNRFVEKIK
DAVDPDGILSPGKQGIWPKKYRQFREVSESSRSTRGKL

Enzyme Prediction     

No EC number prediction in Z517_06369-t43_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA4	34	563	3.9e-143	0.9865900383141762

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
223354	GlcD	6.04e-33	50	554	1	455	FAD/FMN-containing dehydrogenase [Energy production and conversion].
396238	FAD_binding_4	1.35e-32	86	225	1	139	FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
183043	PRK11230	5.48e-09	37	302	14	261	glycolate oxidase subunit GlcD; Provisional
178402	PLN02805	2.95e-08	85	282	133	323	D-lactate dehydrogenase [cytochrome]
397178	FAD-oxidase_C	1.54e-04	450	553	143	247	FAD linked oxidases, C-terminal domain. This domain has a ferredoxin-like fold.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UPK94077.1|AA4	1.56e-268	1	578	1	579
BCS17805.1|AA4	1.34e-264	1	573	1	574
VBB71413.1|AA4	2.19e-258	9	569	8	573
CDP22417.1|AA4	3.56e-240	9	543	8	547
QGA13141.1|AA4	1.11e-228	2	562	3	564

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5FXD_A	3.30e-100	35	562	5	522	Crystal structure of eugenol oxidase in complex with isoeugenol [Rhodococcus jostii RHA1],5FXD_B Crystal structure of eugenol oxidase in complex with isoeugenol [Rhodococcus jostii RHA1],5FXE_A Crystal structure of eugenol oxidase in complex with coniferyl alcohol [Rhodococcus jostii RHA1],5FXE_B Crystal structure of eugenol oxidase in complex with coniferyl alcohol [Rhodococcus jostii RHA1],5FXF_A Crystal structure of eugenol oxidase in complex with benzoate [Rhodococcus jostii RHA1],5FXF_B Crystal structure of eugenol oxidase in complex with benzoate [Rhodococcus jostii RHA1],5FXP_A Crystal structure of eugenol oxidase in complex with vanillin [Rhodococcus jostii RHA1],5FXP_B Crystal structure of eugenol oxidase in complex with vanillin [Rhodococcus jostii RHA1]
1E0Y_A	2.77e-93	35	561	12	553	Structure of the D170S/T457E double mutant of vanillyl-alcohol oxidase [Penicillium simplicissimum],1E0Y_B Structure of the D170S/T457E double mutant of vanillyl-alcohol oxidase [Penicillium simplicissimum]
1W1K_A	3.90e-93	35	561	12	553	STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE: Ile238Thr Mutant [Penicillium simplicissimum],1W1K_B STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE: Ile238Thr Mutant [Penicillium simplicissimum]
1DZN_A	7.69e-93	35	561	12	553	Asp170Ser mutant of vanillyl-alcohol oxidase [Penicillium simplicissimum],1DZN_B Asp170Ser mutant of vanillyl-alcohol oxidase [Penicillium simplicissimum]
1W1J_A	1.52e-92	35	561	12	553	STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE: The505Ser Mutant [Penicillium simplicissimum],1W1J_B STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE: The505Ser Mutant [Penicillium simplicissimum]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P56216|VAOX_PENSI	1.54e-91	35	561	12	553	Vanillyl-alcohol oxidase OS=Penicillium simplicissimum OX=69488 GN=VAOA PE=1 SV=1
sp|P09788|DH4C_PSEPU	9.84e-79	34	556	8	515	4-cresol dehydrogenase [hydroxylating] flavoprotein subunit OS=Pseudomonas putida OX=303 GN=pchF PE=1 SV=3
sp|P94535|GLCD_BACSU	2.30e-17	76	302	31	247	Glycolate oxidase subunit GlcD OS=Bacillus subtilis (strain 168) OX=224308 GN=glcD PE=3 SV=1
sp|P9WIT0|Y2280_MYCTO	3.66e-14	54	305	11	248	Uncharacterized FAD-linked oxidoreductase MT2338 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT2338 PE=3 SV=1
sp|P9WIT1|Y2280_MYCTU	3.66e-14	54	305	11	248	Uncharacterized FAD-linked oxidoreductase Rv2280 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv2280 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000057	0.000004

TMHMM  Annotations     

There is no transmembrane helices in Z517_06369-t43_1-p1.