CAZyme Information: Z517_06018-t43_1-p1

Basic Information

• Species: Fonsecaea pedrosoi
• Lineage: Ascomycota; Eurotiomycetes; ; Herpotrichiellaceae; Fonsecaea; Fonsecaea pedrosoi
• CAZyme ID: Z517_06018-t43_1-p1
• CAZy Family: GH2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
956		107755.87	6.1019

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_FpedrosoiCBS271-37	12573	1442368	46	12527

• Gene Location: location=KN846972:666305-669175(-)

Full Sequence      

MVKHHDFKRCDQSGFCKRNRALADSMTEKGNPESSPYQLDAASIKFKDGRMDGSVIKSLA
DGDAVKLPLTITFLDHGNVRVTVDEEKRRKGEIELRHGSVARKERYNEAAAWALTGGGLQ
PQTTASMEKVSKDVTEVSWGADGHFKAVIRHAPFGIEFWSGEEKHVVFNGRGFLNVEHWR
PKVEKPAADENSTEAQPMEAAEDESTWWDESFGGNTDSKPKGPESVALDITFPGYGHVYG
LPEHAGPLSLKETRGGDGNYDQPYRMYNSDVFEYELDSPMTLYGSIPFMHAHKKDSTVGV
FWLNAAETWVDIVKSKHDTNPLTLGLTGGVVDTHTHWISESGLLDVFVMLGPTPGDVSKS
FGELTGYTAMPALFALAYHQCRWNYVSDEDVKDVDRKFDKFNIPYDVIWLDIEYTDDKKY
FTWDPLNFPDPISMEKQLDETERKLVVIIDPHIKNKEGYFVVDELKTKGLAVKNKENNIF
EGWCWPGSSHWIDAFNPAARAWWKSLFTFDRFKGTQSNVWLWNDMNEPSVFNGPEITMPR
DNLHHGNWEHRDLHNLNGMTFHNATWHALLERKKGEIRRPFVLTRSFYAGSQRSAAMWTG
DNQANWEHLAASIPMILNQGVGGFPFAGADVGGFFGNPSKELQTRWYQAGAFYPFMRGHA
HIDTRRREPYMLGEPYTGIMTQALRLRYSLLPAWYTAFHEAATDGHPIVRAQYFVHPSDE
RGFGIDDQMYLGSTGLLVKPVTVEGGESVDIYLSDDENYYDYFDFTIYAGGSKTHKVDAP
LDKIPLLMQGGHIIPRKDRPRKSSGLMKWDPYTLVVVLDKHGEKAEGTLYVDDGETFEYQ
QGAYIHRQFSFGDGALRSRDIGTKGPKTAGYLKTMKEVKIEKIIVVNAPAAWSSTTELTV
SEDGVKGDRKVDMSYHAAQGNKAAWAVIRSPGTSIGVDWTVQFPESASSSRPKTEL

Enzyme Prediction     

EC	3.2.1.20:27	3.2.1.84:26

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH31	347	794	1.9e-147	0.9953161592505855

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
395838	Glyco_hydro_31	0.0	347	794	1	442	Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.
269889	GH31_GANC_GANAB_alpha	0.0	366	836	1	467	neutral alpha-glucosidase C, neutral alpha-glucosidase AB. This subgroup includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae.
224418	YicI	0.0	131	891	71	765	Alpha-glucosidase, glycosyl hydrolase family GH31 [Carbohydrate transport and metabolism].
269890	GH31_glucosidase_II_MalA	2.16e-144	366	705	1	339	Alpha-glucosidase II-like. Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized in Bacillus thermoamyloliquefaciens where it forms a homohexamer. This subgroup also includes the MalA alpha-glucosidase from Sulfolobus solfataricus and the AglA alpha-glucosidase from Picrophilus torridus. MalA is part of the carbohydrate-metabolizing machinery that allows this organism to utilize carbohydrates, such as maltose, as the sole carbon and energy source.
215408	PLN02763	1.88e-113	352	873	164	669	hydrolase, hydrolyzing O-glycosyl compounds

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAK40395.1|GH31	0.0	2	943	25	957
CAS97680.1|GH31	0.0	2	943	25	957
ACF60497.1|GH31	0.0	2	943	25	957
QVM11559.1|GH31	0.0	1	943	1	934
QMW43538.1|GH31	0.0	2	943	31	966

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5DKX_A	0.0	1	943	4	950	Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495],5DKY_A Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495],5JQP_A Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495]
5DKZ_A	0.0	1	943	4	950	Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495],5DL0_A Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495]
5IEG_A	7.21e-249	2	946	1	914	Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus]
5IEF_A	9.87e-249	2	941	1	909	Murine endoplasmic reticulum alpha-glucosidase II with N-butyl-1-deoxynojirimycin [Mus musculus]
7KRY_A	5.39e-248	2	941	32	940	Chain A, Neutral alpha-glucosidase AB [Mus musculus],7KRY_C Chain C, Neutral alpha-glucosidase AB [Mus musculus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q9US55|GLU2A_SCHPO	2.18e-293	5	914	29	912	Glucosidase 2 subunit alpha OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gls2 PE=1 SV=1
sp|Q9FN05|PSL5_ARATH	2.58e-250	3	942	22	919	Probable glucan 1,3-alpha-glucosidase OS=Arabidopsis thaliana OX=3702 GN=PSL5 PE=1 SV=1
sp|Q94502|GANAB_DICDI	9.46e-248	7	942	29	941	Neutral alpha-glucosidase AB OS=Dictyostelium discoideum OX=44689 GN=modA PE=3 SV=1
sp|Q8BHN3|GANAB_MOUSE	1.38e-247	2	941	33	941	Neutral alpha-glucosidase AB OS=Mus musculus OX=10090 GN=Ganab PE=1 SV=1
sp|P79403|GANAB_PIG	1.75e-245	2	941	33	941	Neutral alpha-glucosidase AB OS=Sus scrofa OX=9823 GN=GANAB PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000057	0.000000

TMHMM  Annotations     

There is no transmembrane helices in Z517_06018-t43_1-p1.