CAZyme Information: YJR013W-t26_1-p1

Basic Information

• Species: Saccharomyces cerevisiae
• Lineage: Ascomycota; Saccharomycetes; ; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae
• CAZyme ID: YJR013W-t26_1-p1
• CAZy Family: GH81
• CAZyme Description: glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
403	BK006943|CGC3	47166.34	9.3163

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_ScerevisiaeS288C	6350	559292	443	5907

• Gene Location: location=BK006943:460382-461593(+)

Full Sequence      

MTGEEWGLTVLSFLVRVGFFLFGIYQDANFKVRYTDIDYFVFHDAAKYVYEGKSPYARDT
YRYTPLLSWLLVPNHYFGWFHLGKVIFVIFDLVTGLIIMKLLNQAISRKRALILESIWLL
NPMVITISTRGNAESVLCCLIMFTLFFLQKSRYTLAGILYGLSIHFKIYPIIYCIPIAIF
IYYNKRNQGPRTQLTSLLNIGLSTLTTLLGCGWAMYKIYGYEFLDQAYLYHLYRTDHRHN
FSVWNMLLYLDSANKENGESNLSRYAFVPQLLLVLVTGCLEWWNPTFDNLLRVLFVQTFA
FVTYNKVCTSQYFVWYLIFLPFYLSRTHIGWKKGLLMATLWVGTQGIWLSQGYYLEFEGK
NVFYPGLFIASVLFFVTNVWLLGQFITDIKIPTQPTVSNKKNN

Enzyme Prediction     

EC	2.4.1.-:14

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT50	127	386	1.5e-95	0.9961832061068703

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
252941	Mannosyl_trans	1.01e-106	127	386	1	259	Mannosyltransferase (PIG-M). PIG-M has a DXD motif. The DXD motif is found in many glycosyltransferases that utilize nucleotide sugars. It is thought that the motif is involved in the binding of a manganese ion that is required for association of the enzymes with nucleotide sugar substrates.
178434	PLN02841	4.76e-81	8	386	11	415	GPI mannosyltransferase
399599	PIG-U	3.52e-05	44	244	32	254	GPI transamidase subunit PIG-U. Many eukaryotic proteins are anchored to the cell surface via glycosylphosphatidylinositol (GPI), which is posttranslationally attached to the carboxyl-terminus by GPI transamidase. The mammalian GPI transamidase is a complex of at least four subunits, GPI8, GAA1, PIG-S, and PIG-T. PIG-U is thought to represent a fifth subunit in this complex and may be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AJR65662.1|GT50	3.19e-302	1	403	1	403
AJR72147.1|GT50	3.19e-302	1	403	1	403
NP_012547.2|GT50|2.4.1.-	3.19e-302	1	403	1	403
AJV45292.1|GT50	3.19e-302	1	403	1	403
AJV44309.1|GT50	3.19e-302	1	403	1	403

PDB Hits     

YJR013W-t26_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P47088|GPI14_YEAST	5.66e-303	1	403	1	403	GPI mannosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GPI14 PE=1 SV=2
sp|Q75C82|GPI14_ASHGO	6.63e-161	1	402	1	397	GPI mannosyltransferase 1 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=GPI14 PE=3 SV=1
sp|Q6FXQ5|GPI14_CANGA	4.09e-153	7	388	8	395	GPI mannosyltransferase 1 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) OX=284593 GN=GPI14 PE=3 SV=1
sp|Q6CRE7|GPI14_KLULA	1.33e-149	8	403	8	401	GPI mannosyltransferase 1 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=GPI14 PE=3 SV=1
sp|Q5AMR5|GPI14_CANAL	6.04e-114	8	389	7	398	GPI mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=GPI14 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000013	0.000000

TMHMM  Annotations     

Start	End
7	26
77	99
131	149
159	181
194	216
266	283
312	331
361	383