CAZyme Information: YBR004C-t26_1-p1

Basic Information

• Species: Saccharomyces cerevisiae
• Lineage: Ascomycota; Saccharomycetes; ; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae
• CAZyme ID: YBR004C-t26_1-p1
• CAZy Family: AA2
• CAZyme Description: GPI-anchor transamidase GPI18

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
433	BK006936|CGC9	50758.77	9.8038

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_ScerevisiaeS288C	6350	559292	443	5907

• Gene Location: location=BK006936:244366-245667(-)

Full Sequence      

MIVGLTLYFVLFRSIQYLLVFLTPIRQFDTSTSLLLNELCSSPSEINSYWNKYFWNKLLS
WDSVFFIKNITSKNGKPQFEHEYAFSQLWTFFVRLFIKSNNDSIYHALRVGVAIENVLFY
LSGIVLYFLTKKIFSQNIRQSQFARTIAKKTSLLFFLTSAAGFLTSIYSEPLSFFFAFVG
IWSRECSISVPVLGQFDISWRYWFPYSFISMACFTLASLNRSNCVLLGIYFIFDLIELTK
NRKFVKAICFPLLSGSLMFSALLYQQYYLPYKTFCPQRGEWCKSQLFSSIFITKTSLYSY
IQSHYWGVGLLKYWTPNNIPNFLFAVPNIIILIYSSIYFSKIYPSYNLKALVWITRALVV
IVCFFAHVQILNRIASFLPLHLWYLADRLVKTSDPKKMENPKGDDKIVKFYIYWLAFWIP
LQTILFAAFLPPA

Enzyme Prediction     

EC	2.4.1.-:3

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT76	6	433	5.5e-109	0.995085995085995

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
282094	Mannosyl_trans2	1.98e-158	2	433	1	439	Mannosyltransferase (PIG-V). This is a family of eukaryotic ER membrane proteins that are involved in the synthesis of glycosylphosphatidylinositol (GPI), a glycolipid that anchors many proteins to the eukaryotic cell surface. Proteins in this family are involved in transferring the second mannose in the biosynthetic pathway of GPI.
227829	COG5542	3.89e-110	3	433	1	408	Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AJP85072.1|GT76	1.98e-316	1	433	1	433
AJQ04974.1|GT76	1.98e-316	1	433	1	433
AJP90335.1|GT76	1.98e-316	1	433	1	433
AJQ03094.1|GT76	1.98e-316	1	433	1	433
AJQ16072.1|GT76	1.98e-316	1	433	1	433

PDB Hits     

YBR004C-t26_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P38211|GPI18_YEAST	3.52e-317	1	433	1	433	GPI mannosyltransferase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GPI18 PE=1 SV=2
sp|Q6FWN4|GPI18_CANGA	8.49e-141	7	433	9	433	GPI mannosyltransferase 2 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) OX=284593 GN=GPI18 PE=3 SV=1
sp|Q757K7|GPI18_ASHGO	3.99e-119	5	433	7	427	GPI mannosyltransferase 2 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=GPI18 PE=3 SV=1
sp|Q6CMW6|GPI18_KLULA	1.37e-114	13	433	21	417	GPI mannosyltransferase 2 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=GPI18 PE=3 SV=1
sp|Q6BRZ9|GPI18_DEBHA	3.41e-63	8	433	10	428	GPI mannosyltransferase 2 OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=GPI18 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.840375	0.159633

TMHMM  Annotations     

Start	End
7	25
108	130
151	168
198	220
247	269
322	339
352	371
410	432