CAZyme Information: XP_001929806.1

Basic Information

• Species: Podospora anserina
• Lineage: Ascomycota; Sordariomycetes; ; Podosporaceae; Podospora; Podospora anserina
• CAZyme ID: XP_001929806.1
• CAZy Family: GT34
• CAZyme Description: Podospora anserina S mat+ genomic DNA chromosome 5, supercontig 6 [Source:UniProtKB/TrEMBL;Acc:B2VLJ0]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1493		167446.06	4.8812

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PanserinaSmat	10888	515849	370	10518

• Gene Location: location=CU607053:315412-319954(+)

Full Sequence      

MLRLSQLPLGLAAILATCLSPAHVGASPSVNVALKAAFPAPPYLVELLETAASDNATAYF
ALLDRVAKGDFVEATTDKTLYEKFVEVLQDDGHMDAEALSTFKLALSMRTAAPRIEAHYQ
YYSTAVEPSLAEDQVGCVQWYLLDGKQYCTPSLDKAHADVKQSSQERTLPFDHKFGAGAK
DIILYADITSSSFGKFHETAKEIAQKGEGSYRIRYKRSAAHPEETLSVNGYGVALTLKRT
DYIVIDDRDTGAAKAQDEAQKPIGASDVVLDDEEEITDIKPLEKSELTPLAMKAASFIMK
SDSPFETLLKLTQDFPKYSTSLGAHNVSEEFEEEHRLNRQVLAPEGVNVLWMNGVQLIDR
QIQPFGLVDLLTRERKLIHGVLDLGLTGEQAVSLLGHSEIAQAKSADDEPRRFDWRDKIE
DGEVIVWLNNIEKDKRYQEFSPSIWTILQSFGGLPQVRKNMFNLVAPVDLTKPEDVTVIV
EQLLVFMKRLIPVRFGFVPLTPTGEAIDQAKVVYYLLDTYGLSATVAYLENSLESKKTSK
ADEGVFKQAIKDRKPKEDATVLAFKDIFTSEHHEKQIHLAKHWVERLRADTEVPPVFFNG
FPIPREENWLRAMNQKLGAELQEIQQGVYFGQIGDETNIEAQFAEKAIARRNTFIYPEDA
RDITILNFNKVYTENAYLFDKMPVVEADKDSTKEDWAALTVITDLSTPDGQKLAYFALKF
RKDSPGVRIDIVHNPKDTSQSASALTLHIKKQEDSLATVNTLLDLETVLDNVSAEADREL
DAALASFLSSVNLKAGNSALILNGRLVGPIPSAEDFKPEDLETFLETERAQRIVPVHKAI
EDLGLGDKISGPLDAAKLTSVTALSGISDLPQGIFDSAPSVRISQFSEFKKEYTSFEVGD
ASKATIFFTAIINPASEGGQKWAAILKVLSELEGVHLRVFLNPTENVQELPIKRFYRYVL
NSAPTFDQDGKVASLSANFAGVPQDTLFVAGMDVPPAWLVTSKVSVDDLDNLRIKDIKAK
RGTEHVEAIYELENILIEGHSREMPSGAPPKGAQLVLGTESNPHIADTIIMANLGFFQFK
ANPGVYNLKLKEGRSSDIFTMVSVGAQGWALAPGDENAEVTLMDFQGTTLYPRLTRNPGM
EGEDVLEPTDPEPAPSGSAMDYLNKGLKFAEGILGKSKPATKSLSETEHAEINIFSVASG
HLYERMLNIMMVSVMRHTNHTVKFWFIEQFLSPSFKDFIPVLAEQYGFKYEMVTYKWPHW
LRQQKEKQREIWGYKILFLDVLFPLSLDKVIFVDADQIVRTDLYDLVQLDLEGKPYGFTP
MCDSRTEMEGFRFWKTGYWANYLRGLPYHISALYVVDLKKFREIAAGDRLRQQYHSLSAD
PNSLANLDQDLPNHMQFQIPIFSLPQEWLWCETWCSDETLGDARTIDLCNNPQTKEPKLE
RARRQVPEWTEYDEEIAELARRNREGKEKKVKGANTKSRRFEEETKGHVVDEL

Enzyme Prediction     

EC	2.4.1.-:29

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT24	1192	1439	5.7e-134	0.9959677419354839

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
133054	GT8_HUGT1_C_like	0.0	1192	1439	1	248	The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
408203	Glyco_transf_24	0.0	1192	1459	1	268	Glucosyltransferase 24. This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
408201	Thioredoxin_14	2.75e-94	413	655	1	248	Thioredoxin-like domain. This is the third out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
408202	Thioredoxin_15	2.70e-72	667	863	1	204	Thioredoxin-like domain. This is the fourth TRXL(thioredoxin-like) domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
399437	UDP-g_GGTase	3.37e-66	1038	1147	1	109	UDP-glucose:Glycoprotein Glucosyltransferase. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CDP29610.1|GT24	0.0	1	1493	1	1493
CAP49306.1|GT24	0.0	1	1493	1	1493
CAD60785.1|GT24	0.0	1	1493	1	1493
VBB81405.1|GT24	0.0	1	1493	1	1493
AEO67685.1|GT24	0.0	1	1461	1	1467

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MU1_A	0.0	23	1486	4	1481	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5MZO_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TRF_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5NV4_A	0.0	23	1486	4	1481	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TRT_A	0.0	23	1486	4	1481	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS2_A	0.0	23	1486	4	1247	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_C Chain C, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_D Chain D, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS8_A	0.0	27	1401	1	1382	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS8_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q09140|UGGG_SCHPO	1.06e-257	26	1459	18	1424	UDP-glucose:glycoprotein glucosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gpt1 PE=1 SV=2
sp|Q9NYU2|UGGG1_HUMAN	1.70e-224	42	1468	59	1532	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3
sp|Q6P5E4|UGGG1_MOUSE	9.53e-221	11	1459	28	1523	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Uggt1 PE=1 SV=4
sp|Q9JLA3|UGGG1_RAT	1.95e-219	11	1459	28	1523	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Uggt1 PE=1 SV=2
sp|Q09332|UGGG_DROME	1.89e-218	42	1462	42	1510	UDP-glucose:glycoprotein glucosyltransferase OS=Drosophila melanogaster OX=7227 GN=Uggt PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000490	0.999494	CS pos: 17-18. Pr: 0.4120

TMHMM  Annotations     

There is no transmembrane helices in XP_001929806.1.