CAZyme Information: XP_001912777.1

Basic Information

• Species: Podospora anserina
• Lineage: Ascomycota; Sordariomycetes; ; Podosporaceae; Podospora; Podospora anserina
• CAZyme ID: XP_001912777.1
• CAZy Family: GT2|GT2
• CAZyme Description: Glyco_transf_20 domain-containing protein [Source:UniProtKB/TrEMBL;Acc:B2AAZ7]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
949		107358.77	6.6366

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PanserinaSmat	10888	515849	370	10518

• Gene Location: location=CU633438:2004306-2007339(+)

Full Sequence      

VSCRQCCAGCLKHYTYVFLYRFLPKTIHFTLPGTPPRGSRSEKPQPNPRPAPPERQPSLF
QPPSITPPHTPTDEKKPSGLFTNEDGLRVHIPTTTAIGEDGVRAPADRSSPTWGGRLDQP
MSRANSPPPPSLIQKARNLHQKAKEMGRAGITQPRTLDRSESHERVFAHANWKIVNADQG
NGGLRNAAEAASREGKVGDCTWVGTLGMPTDALQGTQQLQDIQDKLATEHDMLSVCPSDK
DFDGHYSHFCKQILWPVFHYQIPDNPKSKAYEDHSWKYYVNVNQAFADVIVKNWKRGDVV
WVHDYHLLLVPGMVRKKLPEAKICFFLHVAFPSSEVFRCLAVRKQLLEGMLGANLIGFQI
HEYTRHFLQTCSRLLSAEATPDGLQLEDRFVDVVNLPIGIDPVSLSQHREEDEVKRWLDT
MRERYAGKKLIVARDKLDHVRGVRQKLLSYELFLNKNPEWRDKVVLIQVALSTSEKSELD
ATVSDIVTRVNSSWANLAYQPVVYLKQDIDYAQYLALLSVADALMITSQREGMNLTSHEY
LFCQDGKISEKKHGSLILSEFTGTSSLFGGNELSVNPWDYRACADAIKKALEMEDEEKEM
RWTKLYEAVNHHTGSHWFSEILARLDIVYEQQHRHDQTSVPRLSLNTLVQQYNRTERRLF
ILDFEGTLVSWGPVNQIIPVSPQRTLDVLNDLLLDDRNTIFVMSGRRPEELDRLFRRVPN
LGLIAENGCFLRNCGSTEWTEMADADQIRSWKDSVRGILTYYIERTPGAEIEDRRCSLIF
HYKSAEDYESATRQALDCASHINDACEDQRVHAIPMEGCVLVEPLDWTKSTAAQRIFSDL
RDRMAPDATHTSPVDFLMVVGDGREDEKVFKWANGLGEEGLVEEVVTVSLGTRNTEATAT
MTQGVSGVLMALQRLGSIASVVPTQHRRKSSVRGVILPPDAELQFLPTS

Enzyme Prediction     

No EC number prediction in XP_001912777.1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT20	171	625	5.9e-157	0.9284210526315789

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
340820	GT20_TPS	0.0	175	625	21	462	trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.
395781	Glyco_transf_20	0.0	161	625	13	468	Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex,.
223457	OtsA	6.50e-164	180	625	42	477	Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism].
184712	PRK14501	1.23e-163	182	915	28	723	putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional
215555	PLN03063	5.39e-137	239	870	87	717	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAP60259.1|GT20	0.0	1	949	1	949
CDP22899.1|GT20	0.0	11	949	1	939
VBB71954.1|GT20	0.0	11	949	1	939
AEO53735.1|GT20	0.0	22	919	9	905
AEO70645.1|GT20	0.0	22	919	9	904

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6JBI_A	3.01e-100	154	626	10	463	Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBI_B Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBR_A Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_B Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_D Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_F Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_H Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_K Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_M Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_O Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBW_A Structure of Tps1/UDP complex [Pyricularia oryzae 70-15],6JBW_B Structure of Tps1/UDP complex [Pyricularia oryzae 70-15]
5HVM_A	1.96e-97	154	626	22	475	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVM_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
5HUT_A	3.93e-93	181	625	31	467	Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUT_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUU_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HUU_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HVL_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314],5HVL_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314]
5HUV_A	5.48e-93	181	625	31	467	Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314],5HUV_B Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314]
5DXF_A	7.14e-93	175	622	59	520	Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain [Candida albicans SC5314],5DXF_B Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain [Candida albicans SC5314]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|O14081|TPSX_SCHPO	1.51e-191	114	917	133	943	Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC2E11.16c PE=1 SV=1
sp|Q9UUI7|TPSY_SCHPO	1.38e-190	108	915	107	889	Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC22F8.05 PE=1 SV=1
sp|P38427|TSL1_YEAST	4.29e-163	162	837	336	987	Trehalose synthase complex regulatory subunit TSL1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TSL1 PE=1 SV=1
sp|P38426|TPS3_YEAST	1.17e-161	166	823	308	939	Trehalose synthase complex regulatory subunit TPS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TPS3 PE=1 SV=3
sp|Q54K57|TPSA_DICDI	2.94e-126	191	786	48	628	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] A OS=Dictyostelium discoideum OX=44689 GN=tpsA PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000019	0.000031

TMHMM  Annotations     

There is no transmembrane helices in XP_001912777.1.