CAZyme Information: XP_001903997.1

Basic Information

• Species: Podospora anserina
• Lineage: Ascomycota; Sordariomycetes; ; Podosporaceae; Podospora; Podospora anserina
• CAZyme ID: XP_001903997.1
• CAZy Family: GT69
• CAZyme Description: Podospora anserina S mat+ genomic DNA chromosome 4, supercontig 3 [Source:UniProtKB/TrEMBL;Acc:B2AEA8]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
855	CU633456|CGC1	97934.82	6.0081

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PanserinaSmat	10888	515849	370	10518

• Gene Location: location=CU633456:97063-99725(-)

Full Sequence      

MPPQPHTTHPLTTNWQFHRLGNPPTKWHPVPHLPSDIHTELINSSLLSHPFLDLNELATS
WVADQTWIYRLTFPTPAHNPDAVIDLVFEGLVTFATITLNGRVIKQTDNMFVCWRVNIND
FVAGEEENILEITFDNARERGLRLVKDHPEHEFIVHQTEVSRGPVRKAQYHWGWDWGPTL
MTYGLWRPVRIEVYESRIGEVAVKYNVDLSEGGEEPEVEIGLWVEIVGRAGWAEVEVGFE
GRTMVAFTGEQGKLIKNGEHPETWEYSASMVRLEGAKLWWPRGYGGQNLYDVRVRIFDAE
GGTVLAEHNQRVGFRKAELVQERDGYGQSFYFRVNDIDVFALARTGSLPTPSCHKLPPIG
TGIGYRMRLRTDFMFACASYPTYLEFLKSIEMETRQNVTRLRSHPSIVLWCGSNEDYQIQ
ERYQLDNNRSDNDPESWLKSSFPARYIYEELLPRIVREESPCPNTLLYHPCSPFGTGAST
TLEVDPTVGDIHQWNFWHGEAKPFQCLPEMGGRFVSEFGMEAYPHFETVQRFVTDPKELY
PGSKTLDFHNKAIGYERRLMAYLGENYRLVYDIKGFIHLTQILQADSMATAYKSWRRAWQ
TQGGKGRNCGGVLVWQLNDCWPTISWAVVDYYGIKKPAWYAMKRALAPIAVGVSRAFWDW
TMRPADNLWKRHTGHVDPTLSTKKVVYDVWVSSDGTTHPNKENIEATVRTRFISVATGKD
ILFDIPESKTVSIKPNGVTDISLSSELNWGGKQEEPIVIYVSLWINNEKVSSDCSWPDPI
KYLDLSERGLRLEYPAENEVTIRTTKPVKGFVFSEKEGVKLRDNGFDVVPGEIVTVQVEG
IKVRELEWTFVGQGQ

Enzyme Prediction     

EC	3.2.1.25:3	3.2.1.25:3

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
225789	LacZ	6.45e-39	9	699	13	673	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
407658	Mannosidase_ig	5.30e-10	687	782	3	91	Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
395572	Glyco_hydro_2	4.81e-05	250	315	45	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
407625	Ig_mannosidase	2.93e-04	798	839	15	57	Ig-fold domain. This Ig-like fold domain is found in mannosidase enzymes.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CDP28114.1|GH2	0.0	1	855	1	855
CAP61774.1|GH2	0.0	1	855	1	855
AEO64472.1|GH2	0.0	6	853	4	881
AEO59187.1|GH2	1.65e-311	6	853	4	897
QBZ66458.1|GH2	6.58e-268	7	853	4	897

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5N6U_A	2.88e-103	11	682	29	689	Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_B Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_C Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_D Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12]
2VJX_A	1.66e-85	11	651	11	656	Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A	1.72e-85	11	651	13	658	Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A	1.75e-85	11	651	13	658	Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A	4.46e-85	11	651	11	656	Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|A1D911|MANBB_NEOFI	4.14e-224	10	853	8	845	Beta-mannosidase B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=mndB PE=3 SV=1
sp|Q4WAH4|MANBB_ASPFU	3.30e-223	10	853	8	845	Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mndB PE=3 SV=1
sp|B0YBU9|MANBB_ASPFC	3.30e-223	10	853	8	845	Beta-mannosidase B OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=mndB PE=3 SV=1
sp|Q5B7W2|MANBB_EMENI	1.40e-221	7	853	5	843	Beta-mannosidase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=mndB PE=1 SV=2
sp|Q0CCA0|MANBB_ASPTN	5.65e-218	11	853	9	843	Beta-mannosidase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mndB PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000072	0.000000

TMHMM  Annotations     

There is no transmembrane helices in XP_001903997.1.