CAZyme Information: TSTA_099760-t26_1-p1

Basic Information

• Species: Talaromyces stipitatus
• Lineage: Ascomycota; Eurotiomycetes; ; Trichocomaceae; Talaromyces; Talaromyces stipitatus
• CAZyme ID: TSTA_099760-t26_1-p1
• CAZy Family: GH71
• CAZyme Description: conserved hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
611		66897.18	4.5251

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_TstipitatusATCC10500	12629	441959	146	12483

• Gene Location: location=EQ962658:726319-728598(-)

Full Sequence      

MLIKDDLDNGDNVLNVGGELLHHDKCICIGRNTMRLTRLYISFFVYHATSQSLLRFASPD
HDVQAISSESEQNDAEHMASHGAQSSFVPLETTEQSSVSPFRVVGQSGVPAMAAALMPNG
NVVFIDKVENYTQLVLDNGQYAYSSEYNLTSNTAHGLGYQTNAFCSGGSFLADGRLVSVG
GNGPLPDIDPTVGDGFQGIRYLERGAYYGDWYEPGHTLSTPRWYASVQMLQGKELFVASG
SLNGLDPMRSENNNPTFEILDQDGIPATGSIILPILSDNQPYYMYPFLHLLKNGHLFIFV
SRSAEVYNPYDLTTSRQLPNLPGAYRTYPNTGGSVILPLSKKNDWEPEIMVCGGGAYADI
SSPADRTCGRIQPLSENPEWHMEEMPEPRVMVEGLLLPDGKVLWLNGARRGAQGFGTAQE
PCFGAFIYDPEQPTGSRWALEGTSDIPRLYHSVALLLLDGTVMVAGSNPMEQPLLEPNYN
SPATAYATEFRVEIYTPPYLLGANASKRPQNIQLSQVDLIADGESFFISFTSTANATDLK
IALYHGGFVTHSLHMGQRLIYLDHEGFAPGFDEQFVSVFMPPSSSISPSGPYVIYVVLDG
VPGLGQFVMVR

Enzyme Prediction     

No EC number prediction in TSTA_099760-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA5	99	610	6.8e-141	0.9467140319715808

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
399910	Glyoxal_oxid_N	2.35e-46	112	354	1	243	Glyoxal oxidase N-terminus. This family represents the N-terminus (approximately 300 residues) of a number of plant and fungal glyoxal oxidase enzymes. Glyoxal oxidase catalyzes the oxidation of aldehydes to carboxylic acids, coupled with reduction of dioxygen to hydrogen peroxide. It is an essential component of the extracellular lignin degradation pathways of the wood-rot fungus Phanerochaete chrysosporium.
401164	DUF1929	7.26e-15	523	610	9	91	Domain of unknown function (DUF1929). Members of this family adopt a secondary structure consisting of a bundle of seven, mostly antiparallel, beta-strands surrounding a hydrophobic core. The 7 strands are arranged in 2 sheets, in a Greek-key topology. Their precise function, has not, as yet, been defined, though they are mostly found in sugar-utilising enzymes, such as galactose oxidase.
199882	E_set_GO_C	4.31e-10	504	610	2	103	C-terminal Early set domain associated with the catalytic domain of galactose oxidase. E or "early" set domains are associated with the catalytic domain of galactose oxidase at the C-terminal end. Galactose oxidase is an extracellular monomeric enzyme which catalyzes the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalyzing a two-electron transfer reaction during the oxidation of primary alcohols to corresponding aldehydes. The second redox active center necessary for the reaction was found to be situated at a tyrosine residue. The C-terminal domain of galactose oxidase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QGA21118.1|AA5	0.0	34	609	1	581
QKX63834.1|AA5	3.44e-266	101	611	58	568
QSS69861.1|AA5|CBM18	7.81e-232	101	611	114	628
QSS64055.1|AA5|CBM18	1.27e-230	101	611	114	628
QRC90698.1|AA5|CBM18	6.26e-223	105	610	322	826

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4UNM_A	1.12e-13	196	610	231	614	Structure of Galactose Oxidase homologue from Streptomyces lividans [Streptomyces lividans],4UNM_B Structure of Galactose Oxidase homologue from Streptomyces lividans [Streptomyces lividans]
5LXZ_B	7.74e-13	285	610	298	603	W288A mutant of GlxA from Streptomyces lividans: Cu-bound form [Streptomyces lividans TK24]
5LQI_A	7.80e-13	285	610	303	608	W288A mutant of GlxA from Streptomyces lividans: apo form [Streptomyces lividans 1326],5LQI_B W288A mutant of GlxA from Streptomyces lividans: apo form [Streptomyces lividans 1326]
2EIC_A	1.10e-09	164	610	227	637	Chain A, Galactose oxidase [Fusarium graminearum]
1GOF_A	1.91e-09	164	610	227	637	NOVEL THIOETHER BOND REVEALED BY A 1.7 ANGSTROMS CRYSTAL STRUCTURE OF GALACTOSE OXIDASE [Hypomyces rosellus],1GOG_A NOVEL THIOETHER BOND REVEALED BY A 1.7 ANGSTROMS CRYSTAL STRUCTURE OF GALACTOSE OXIDASE [Hypomyces rosellus],1GOH_A NOVEL THIOETHER BOND REVEALED BY A 1.7 ANGSTROMS CRYSTAL STRUCTURE OF GALACTOSE OXIDASE [Hypomyces rosellus],2EIE_A Chain A, Galactose oxidase [Fusarium graminearum],2JKX_A Chain A, GALACTOSE OXIDASE [Fusarium graminearum],2VZ1_A Chain A, GALACTOSE OXIDASE [Fusarium graminearum],2VZ3_A Chain A, Galactose Oxidase [Fusarium graminearum]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q3HRQ2|GLOX_VITPS	8.17e-73	103	608	20	519	Aldehyde oxidase GLOX OS=Vitis pseudoreticulata OX=231512 GN=GLOX PE=2 SV=1
sp|Q9FYG4|GLOX1_ARATH	4.63e-58	107	610	105	614	Aldehyde oxidase GLOX1 OS=Arabidopsis thaliana OX=3702 GN=GLOX1 PE=2 SV=1
sp|A0A2H4HHY6|GLOX_ARTAN	7.60e-55	107	608	77	591	Putative aldehyde oxidase Art an 7 OS=Artemisia annua OX=35608 PE=1 SV=1
sp|D4AUF1|WSCD1_ARTBC	1.48e-49	160	610	480	903	WSC domain-containing protein ARB_07867 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_07867 PE=1 SV=1
sp|Q01772|GLOX_PHACH	1.42e-47	107	609	35	548	Aldehyde oxidase GLOX OS=Phanerodontia chrysosporium OX=2822231 GN=GLX PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999834	0.000177

TMHMM  Annotations     

There is no transmembrane helices in TSTA_099760-t26_1-p1.