CAZyme Information: TRIVIDRAFT_56881-t45_1-p1

Basic Information

• Species: Trichoderma virens
• Lineage: Ascomycota; Sordariomycetes; ; Hypocreaceae; Trichoderma; Trichoderma virens
• CAZyme ID: TRIVIDRAFT_56881-t45_1-p1
• CAZy Family: GH5
• CAZyme Description: glycoside hydrolase family 2 protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
885	ABDF02000090|CGC5	99511.92	5.2452

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_TvirensGv29-8	12405	413071	0	12405

• Gene Location: location=ABDF02000090:894387-897209(-)

Full Sequence      

MSRQSTQLVSGWTFRQHQGPSTEWLPVEKVPTQVHTDLLANKKIPDPFVDLNERAVQWIG
DKDWEYQVTFTPDAVEGENVTRDLVFSGLDTFATVYLNDEKVLETENMFVSYRVNVTDGI
KAGSDNTLRIVFHSAIVRGEELIKEHGHEHNFYVRQTERSRVPVRKAQYNWGWDWGPILM
TAGPWKPVTLETYVARIDDVWAQSEVSEDLSSVSGSIFARVAGVPNQDAQVSVALSLDGQ
TVFQQSVDASLAKDGLIRVPFKLETPKLWYPMGYGSQPRYLLDAKLHHKASGAKEIDSQS
KSIGFRRTELIQEPDAHGKSFYFRINNVDVFAGGSCWIPADSYLAGVPAERYYEWAKLMA
EGNQVMLRVWGGGVYEEDALIEACDQFGILVFHDFQFACASYPAYPSYLKTLEEEARQQI
QRLRTHPSVIAWAGNNEDYQVQERYRLDYDFENKDPESWLKSSFPARYIYEHLLPTWVEQ
EDPGKIYHPSSPWGDGKPTADPTVGDIHQWNIWHGTMNKYQEAANMGGRFVSEFGMEAYP
HLSTTRRMASDPAQLYPGSMVLDAHNKAIGHERRMISYVVDNFRPRLDLGGYTHLTQIVQ
SETMRAAYKAWRRQWGKPGARQCGGVLVWQLNDCWPTMSWAVVDYYLIKKPAYYAISRAL
RSVDVGVHRTFHDWTQTGDWVDENSGLITGQVDQTLPARKGTFDVWVVSNDTKPVELSLV
VRFISVRSGKDIVDPIKSTITAAANSTTDVLQGRALPPPFSLAEYDPYVVHAAITDASTG
ALVAQDTAWPDPIKFLDLSNRGISFEVSPAKDEVVVSAEKPVKGFVFEEVEGLKLSDNGF
DIVPGEKHTVKVEGALTADQLLWTCIGAPEASLPISGASSSLPLR

Enzyme Prediction     

EC	3.2.1.25:3

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	2	677	1e-81	0.6316489361702128

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
225789	LacZ	3.62e-73	1	665	8	634	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
407658	Mannosidase_ig	7.00e-14	701	794	1	90	Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
395572	Glyco_hydro_2	3.70e-08	195	306	1	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
407625	Ig_mannosidase	2.03e-06	802	861	3	67	Ig-fold domain. This Ig-like fold domain is found in mannosidase enzymes.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UKZ51991.1|GH2	0.0	1	885	1	895
UKZ77816.1|GH2	0.0	1	885	1	895
QYS99024.1|GH2	0.0	1	885	1	895
UKZ88363.1|GH2	0.0	1	884	1	896
QLI66193.1|GH2	0.0	7	875	7	876

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5N6U_A	1.41e-130	29	861	47	819	Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_B Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_C Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_D Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12]
2VJX_A	3.19e-119	8	850	11	814	Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A	3.35e-119	8	850	13	816	Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A	3.43e-119	8	850	13	816	Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A	8.94e-119	8	850	11	814	Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|A1CGA8|MANBB_ASPCL	2.40e-285	8	859	9	835	Beta-mannosidase B OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=mndB PE=3 SV=1
sp|Q0CCA0|MANBB_ASPTN	7.28e-284	8	859	9	832	Beta-mannosidase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mndB PE=3 SV=2
sp|Q2TXB7|MANBB_ASPOR	7.53e-284	8	859	9	834	Beta-mannosidase B OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=mndB PE=3 SV=3
sp|B8NW36|MANBB_ASPFN	1.51e-283	8	859	9	834	Beta-mannosidase B OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) OX=332952 GN=mndB PE=3 SV=1
sp|A1D911|MANBB_NEOFI	8.91e-283	4	859	5	835	Beta-mannosidase B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=mndB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000058	0.000001

TMHMM  Annotations     

There is no transmembrane helices in TRIVIDRAFT_56881-t45_1-p1.