logo
sublogo
You are browsing environment: FUNGIDB
help

CAZyme Information: TPX46423.1

You are here: Home > Sequence: TPX46423.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Synchytrium endobioticum
Lineage Chytridiomycota; Chytridiomycetes; ; Synchytriaceae; Synchytrium; Synchytrium endobioticum
CAZyme ID TPX46423.1
CAZy Family GH5
CAZyme Description Ceramide glucosyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A507D4M9]
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
2424 266345.72 7.3025
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_SendobioticumMB42 8031 N/A 0 8031
Gene Location Start: 33941; End:42766  Strand: +

Full Sequence      Download help

MPTIDFSIPK  RLTQRTSKES  IRQLVNGCIE  KSETSITLTL  APYLASHDRS  CSHEHHQYWV60
GRDDIAIIPN  FLPSPAKAIL  DIVLNIRTTS  KTRIMFYLTR  SNNIIWRGTV  LTRAASTIME120
VPSCLCIKNV  ITSSTHSACS  RSGGSEACVA  SFGVMMWIIM  LQFCLWAAVL  IRTRYSNPPL180
PTSASTPSAS  QSHSTTCKPH  PTSPGVTVLR  PLKGVDNQLE  ENLASAFRQA  YPEYQVIMTV240
ANRRDPAVAV  AKRMIERYPD  VDASIVIGNP  DLPEVGPNPK  VCNLLPGYDL  AKHDIIWIVD300
SNVILPSIHT  LGRSVDALQG  PNIGLVHHAP  VASHPETFGS  RVEMIFLNTA  HCKMYLTINY360
VAVSSCINGK  SNMFRKSDLE  RAAKGGLSHF  ARYLSEDNIM  GEKIWAIGLR  HATSGDFAMQ420
HLGRSLSLVG  YFRRRVRWIR  IRKYVVTAAT  LIEPFTESIV  CGVLALYGFS  HWLGWNVKLQ480
MLFITSHFMG  WLLSDVIIAY  TINPSMFSNT  SNSGSVVYEC  LLYLVAWIVR  ECMALPLWVT540
GMAGSVIEWR  GSLDDRNTFL  VYILNRSKMT  LNVGKGQHAI  MGARKESRKV  IPATVDHRFE600
SKPALDLVFR  QAWEQLNERS  EHIFRRHIYI  QSIVLTTGNA  AGTDTRPDVK  TNGADGLPAP660
VSAKITPEEL  DPNKTDSDPQ  GPESKRRVYV  NVNPQPPFAH  VSHVGNQIRT  SKYTLVTFIP720
KNVFEQLRSV  ANFYFISLVI  LQSFDPFKNV  DFALTAAPIL  FILGVTALKD  AFEDYKRHEA780
DTRANNTRTY  LLSNWKNVNP  RPENAAFQFA  ALAFYLSSAI  SYVFQLLGKP  IIRLIRPRML840
QESKISNSGD  FPPYITFGDY  PRCAGDVAQA  TYDGVSQDSS  SANPNADVAS  SADVSGSRVS900
NICKSSRGGT  SQQLRDSSNA  ISSQSSQPKA  EKMGTTATTD  PVWKLSLWQD  AKVGDWVFIR960
ENDPIPADVV  VVSTSEPDNV  CYVETKNLDG  ETNLKIRRGI  TELAAVKTPA  QCAQVKLVID1020
SELPSANLYT  YSGVATVYPQ  ATPASERGAG  KVVPIAPVGI  LLRGCVLRNT  GWIIGIVIYT1080
GVETKVMLNS  GETPSKRSKI  QRTLNPIIVL  NFVILVALCL  INACAAAIYL  GAYRNEGSLW1140
NLGDSNSTLT  QTILDFFIAM  IIYQNIIPIA  LYVSVEVAKT  IQSVFIYWDD  DMYDSEADKH1200
VVPHTYNLCD  DLGQIEYIFS  DKTGTLTANV  MEFRMCSING  VVYGDGYITE  AKIGAMQREG1260
VTDFDKGEML  SKVAGDEKAM  RNALVKDLKA  RYIDNKRLSF  VDMNLIKDLQ  EEEEQARAIR1320
EFFILLACCH  TLLVDTPKDS  AEANTNSNTA  KKLIYKAQSP  DEAALVAAAR  DVGVAFVKRA1380
QNSITVDVYS  EERTYQVLNV  LEFNSDRKRM  SVILRDAEGR  LVLLCKGADS  VIYERLVRGT1440
DQALADKTSA  DLEGFANDGL  RTLCLAWRII  PDEVYQSWAE  TYLSAQAQIT  DREKAIDAAA1500
ELIEKDLVLL  GATAIEDKLQ  DGVPDCIALL  AQAGIKIWVL  TGDKVETAIN  IGFACNLLTG1560
TMVLIVVRAT  TAKATSDQLK  SALNRFWDEN  GGAVEGEAHA  LIIDGESLKY  ALEADCREFL1620
LELGCRCKAV  VCARVSPLQK  ARVVQLVRKG  LNVMTLAIGD  GANDVSMIQE  AEVGVGISGK1680
EGLQAVMASD  YAIPQFRFLS  RLLLVHGKWA  YVRTSGLIFN  YFYKNIMWLF  ILFWYQFESG1740
FSADVITDFT  YGQFYNTLFT  LLPNIYIGTF  DQDVNDALSL  KLPEIYQKGI  RNDLFTNEQV1800
WIYIADGIYQ  SVIVYWGVSF  LFGVDTDPRG  YSGNKDAMGT  IMAWAAVLIA  NFYMAIGTYS1860
WTWIAWIALI  ATLAMWGAYV  TTYAFNVAGL  AYGQIPTLYQ  QPAFYFVIVL  IIIIAFLPRL1920
LAATARIMLW  PSDTDIVREM  QKYDLTGLES  TAAKEGRMKL  NKDPGPPDTA  VDDVGVEVVG1980
NEQAVADESG  IWAAKRNPVF  GAVPPPEPAG  APAITIDDVA  AIPLTTVNNS  NTGATGATLN2040
HAGSGQITPP  RVVRDSVGNA  GQSSNQGDQK  PGSDAPKLAV  DTTPATLNNG  IPTLPAYHPQ2100
NDPQAHLRGR  TRVSSNRRTS  FHLATLPARL  VGEFVRSVPR  RMRAVSTTHQ  DALHTPQRSQ2160
GTIVYMENEH  VGRIANTGFS  FSHEAGMEGV  VSPIRVSAGS  RSRLRGLQDR  APQNSERLSL2220
GDSLRKSLHM  TPRNRNSSRE  PLNVGNTDVT  GHPHGNTAGG  ETARPSNAGR  ERKFSGQKMP2280
IRLPFLYNHH  NQQQTPYMSE  PSLNQSYETH  SHRGSIPPGS  HSTGIGYGYP  PMAPSNDNTS2340
NPHQPPPATT  ERTVQASSQL  AVAPDIEPLT  RSPAASNTGT  EGQSASGVPA  LPLLGQSLTV2400
STPSSDGLKS  LSPNDGRETT  DPRP2424

Enzyme Prediction      help

No EC number prediction in TPX46423.1.

CAZyme Signature Domains help

Created with Snap121242363484606727848969109012121333145415751696181819392060218123021233GT21
Family Start End Evalue family coverage
GT21 204 442 2.3e-81 0.9957081545064378

CDD Domains      download full data without filtering help

Created with Snap121242363484606727848969109012121333145415751696181819392060218123027041939ATPase-Plipid7051818P-type_ATPase_APLT_Dnf-like6831943PLN031907061816P-type_ATPase_APLT9351960MgtA
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
273734 ATPase-Plipid 0.0 704 1939 2 1057
phospholipid-translocating P-type ATPase, flippase. This model describes the P-type ATPase responsible for transporting phospholipids from one leaflet of bilayer membranes to the other. These ATPases are found only in eukaryotes.
319770 P-type_ATPase_APLT_Dnf-like 0.0 705 1818 1 836
Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C. Aminophospholipid translocases (APLTs), also known as type 4 P-type ATPases, act as flippases, and translocate specific phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of biological membranes. Yeast Dnf1 and Dnf2 mediate the transport of phosphatidylethanolamine, phosphatidylserine, and phosphatidylcholine from the outer to the inner leaflet of the plasma membrane. This subfamily includes mammalian flippases such as ATP11C which may selectively transports PS and PE from the outer leaflet of the plasma membrane to the inner leaflet. It also includes Arabidopsis phospholipid flippases including ALA1, and Caenorhabditis elegans flippases, including TAT-1, the latter has been shown to facilitate the inward transport of phosphatidylserine. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.
215623 PLN03190 0.0 683 1943 68 1156
aminophospholipid translocase; Provisional
319838 P-type_ATPase_APLT 0.0 706 1816 2 805
Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, Neo1p, and human ATP8A2, -9B, -10D, -11B, and -11C. Aminophospholipid translocases (APLTs), also known as type 4 P-type ATPases, act as flippases, and translocate specific phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of biological membranes. Yeast Dnf1 and Dnf2 mediate the transport of phosphatidylethanolamine, phosphatidylserine, and phosphatidylcholine from the outer to the inner leaflet of the plasma membrane. Mammalian ATP11C may selectively transports PS and PE from the outer leaflet of the plasma membrane to the inner leaflet. The yeast Neo1p localizes to the endoplasmic reticulum and the Golgi complex and plays a role in membrane trafficking within the endomembrane system. Human putative ATPase phospholipid transporting 9B, ATP9B, localizes to the trans-golgi network in a CDC50 protein-independent manner. It also includes Arabidopsis phospholipid flippases including ALA1, and Caenorhabditis elegans flippases, including TAT-1, the latter has been shown to facilitate the inward transport of phosphatidylserine. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.
223550 MgtA 2.05e-135 935 1960 142 911
Magnesium-transporting ATPase (P-type) [Inorganic ion transport and metabolism].

CAZyme Hits      help

Created with Snap12124236348460672784896910901212133314541575169618181939206021812302204551CDS10611.1|GT21203550ANB13640.1|GT21155552QRW00262.1|GT21147552QRV86216.1|GT21147552QRW14784.1|GT21
Hit ID E-Value Query Start Query End Hit Start Hit End
CDS10611.1|GT21 6.84e-102 204 551 54 394
ANB13640.1|GT21 9.86e-80 203 550 106 475
QRW00262.1|GT21 1.07e-79 155 552 16 432
QRV86216.1|GT21 1.45e-79 147 552 22 432
QRW14784.1|GT21 4.94e-79 147 552 22 432

PDB Hits      download full data without filtering help

Created with Snap1212423634846067278489691090121213331454157516961818193920602181230270619396LCP_A70619437DRX_A70619407KY5_A68318846K7G_A94819466PSY_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
6LCP_A 6.23e-269 706 1939 111 1340
Chain A, Phospholipid-transporting ATPase [Thermochaetoides thermophila DSM 1495],6LCR_A Chain A, Phospholipid-transporting ATPase [Thermochaetoides thermophila DSM 1495]
7DRX_A 7.78e-262 706 1943 194 1417
Chain A, Phospholipid-transporting ATPase DNF1 [Saccharomyces cerevisiae S288C],7DSH_A Chain A, Phospholipid-transporting ATPase DNF1 [Saccharomyces cerevisiae S288C],7DSI_A Chain A, Phospholipid-transporting ATPase DNF1 [Saccharomyces cerevisiae S288C],7F7F_A Chain A, Phospholipid-transporting ATPase DNF1 [Saccharomyces cerevisiae S288C],7KY6_A Chain A, Phospholipid-transporting ATPase DNF1 [Saccharomyces cerevisiae S288C],7KYB_A Chain A, Phospholipid-transporting ATPase DNF1 [Saccharomyces cerevisiae S288C],7KYC_A Chain A, Phospholipid-transporting ATPase DNF1 [Saccharomyces cerevisiae S288C],7WHV_A Chain A, Phospholipid-transporting ATPase DNF1 [Saccharomyces cerevisiae S288C],7WHW_A Chain A, Phospholipid-transporting ATPase DNF1 [Saccharomyces cerevisiae S288C]
7KY5_A 8.83e-260 706 1940 232 1457
Chain A, Phospholipid-transporting ATPase DNF2 [Saccharomyces cerevisiae S288C],7KY7_A Chain A, Phospholipid-transporting ATPase DNF2 [Saccharomyces cerevisiae S288C],7KY8_A Chain A, Phospholipid-transporting ATPase DNF2 [Saccharomyces cerevisiae S288C],7KY9_A Chain A, Phospholipid-transporting ATPase DNF2 [Saccharomyces cerevisiae S288C],7KYA_A Chain A, Phospholipid-transporting ATPase DNF2 [Saccharomyces cerevisiae S288C]
6K7G_A 4.25e-203 683 1884 39 1016
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class1) [Homo sapiens],6K7H_A Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class2) [Homo sapiens],6K7I_A Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class2) [Homo sapiens],6K7J_A Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class1) [Homo sapiens],6K7K_A Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ADP-Pi state) [Homo sapiens],6K7L_A Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E2P state class2) [Homo sapiens],6K7M_A Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E2Pi-PL state) [Homo sapiens],6K7N_A Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1P state) [Homo sapiens]
6PSY_A 3.12e-199 948 1946 299 1247
Cryo-EM structure of S. cerevisiae Drs2p-Cdc50p in the autoinhibited apo form [Saccharomyces cerevisiae W303]

Swiss-Prot Hits      download full data without filtering help

Created with Snap121242363484606727848969109012121333145415751696181819392060218123027061939sp|Q09891|ATCX_SCHPO7061943sp|P32660|ATC5_YEAST7061940sp|Q12675|ATC4_YEAST6811938sp|O36028|ATCZ_SCHPO6791966sp|Q9XIE6|ALA3_ARATH
Hit ID E-Value Query Start Query End Hit Start Hit End Description
sp|Q09891|ATCX_SCHPO 7.06e-275 706 1939 88 1295
Putative phospholipid-transporting ATPase C24B11.12c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC24B11.12c PE=3 SV=1
sp|P32660|ATC5_YEAST 4.00e-261 706 1943 194 1417
Phospholipid-transporting ATPase DNF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DNF1 PE=1 SV=2
sp|Q12675|ATC4_YEAST 4.54e-259 706 1940 232 1457
Phospholipid-transporting ATPase DNF2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DNF2 PE=1 SV=1
sp|O36028|ATCZ_SCHPO 9.14e-238 681 1938 104 1317
Putative phospholipid-transporting ATPase C4F10.16c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC4F10.16c PE=3 SV=1
sp|Q9XIE6|ALA3_ARATH 9.48e-217 679 1966 30 1151
Phospholipid-transporting ATPase 3 OS=Arabidopsis thaliana OX=3702 GN=ALA3 PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000031 0.000000

TMHMM  Annotations      download full data without filtering help

Start End
149 171
444 466
481 503
749 768
806 828
1107 1129
1153 1175
1715 1737
1800 1822
1842 1864
1868 1890
1903 1922