CAZyme Information: TPX45703.1

Basic Information

• Species: Synchytrium endobioticum
• Lineage: Chytridiomycota; Chytridiomycetes; ; Synchytriaceae; Synchytrium; Synchytrium endobioticum
• CAZyme ID: TPX45703.1
• CAZy Family: GH46
• CAZyme Description: 1,3-beta-glucanosyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A507D2K7]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1530		167163.14	7.0787

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_SendobioticumMB42	8031	N/A	0	8031

• Gene Location: location=QEAN01000148:24832-30982(-)

Full Sequence      

MLSKLTRTALYGVLNPPSARWYSHQPSRPLKHENSEAPSVARGIQTLNPIVIKGNKLFDS
ITQDQFFIRGVAYQPLLNGKIIDPISNARRDVWRRDLELMKDLGVNVVRVYEVDADVEHD
EFMKEIEANQIYLLLDVGSGQASINRKAPSYTVKMLKRYMATVDAFSKYKNLMAFVGGNE
VINQGSNTNAAPFVKALIRDLKAHIKKTAPRPIPVGYAATDDDVTRTDVAKYFACGNEST
TADFLGINLYEWCGNSTYEQSGYKDRTADFKNYPLPVFLSEYGCNQPLPRAFTEVSAIYG
PEMARVFSGGIVYEFSEEHNNYGLVNVTRTTATPLRDYYIYKKALADVHPRGMKMAEQSI
RKSTTTCPPQSDTWFATTTLPPTPNECICDAMMESLSCVASVELKGADSSVKELTLSKAC
GMLASQSAADACQEIAPGDGTTDQYGKYSACSFDQKVSYITNKYYFKQPLRVRSQACNFG
GMAHLVTPSRRDMDDSHCVSYSPDEGSTSSPRPDSGSSCLHGGKAVLGSVVASRSSKILA
ADDDKGRDQRGDFFMSSESDRRTTATAAAGPVSSYSITSTGDNDAGTEPFPTLPSPHVYP
ATTASSARPLLSPLGFVPFTTGKPRDTTNPATYTTSTSGIDRSTGTNNNGHAVNQAHASP
SSTSHSQPQNSATLVGRSQARPTSAQVDSMSSYSIPPSNVHLLPPAPPLSIFASHPTFAN
PTTPQPNTKIVSSTHSSRTASPIPSNRPSHAPPQMLSSTSAGPYPRDQAGTPLPAPTTVN
PFVSSQQSSLYVAPPLKKDAASTPSGARGRITTTPQPPSSTTTSTPSANSGNILMPMVPS
IPLTAAQIMPSYSSTSINSSHVSSTVIPPPTPPPPPSTNKGYLLSHIDGLFDDHESAMRS
HHSNVLPRGQMSHHISSIPQQAPSLIHQQPVSKNDDAVIIIDEDSWIRKRPSKPQEETLG
QVLGLKRLAESNTNGPDDRKKRKIGDITVINDDSLNYIPVDVGEKFLGHILYTGATVSIG
NSNNIKQFLLPPFSDKDHYATIDVRIPAKYLSFKDNIAVDNMAIWGTDVYTDDSDVVAMA
IHAGFFRPYDYVDKQTIGLNRGSSGSVENMNETITKIDVKTEPNDGKGSSDSGRSNSKTV
SSSGSASCSYQEADVSKPANDLRDCSSNSTSENISPLPNGITHDMDDKTRRRICSPPLEP
IQGEFNPKTNSPAHDITVTLRILPRLRHYYPSTRHGITTRGWGGSHDGESLRVEGVRVEK
DKPCFDSAGRKQGAKEWNIFARSIALEMMGLGPDGHPQNGEVDHHTRDHGWETECSLGGG
VTIVFSPLSGVACLKYAPKLLLDWPPHLRDLFSAIQNPIYGQLVSIDESADSFSRAEVRQ
AGLEGWPYFRMKLNRGDALCLEGDDDKSYVLKLEPPGKIHLRRRTYSFSDEPLQLELDYH
QISWEGDGLMVSDTRAIPIARFYCVITIGRVITDLQSPVSILAKRWKEVTDNHHLFSEFL
PSLMSWRSREEGIGWDHDRLSDSKYRGTKF

Enzyme Prediction     

EC	2.4.1.-:30

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH72	46	347	1.9e-116	0.9839743589743589

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397351	Glyco_hydro_72	9.10e-134	49	348	11	314	Glucanosyltransferase. This is a family of glycosylphosphatidylinositol-anchored beta(1-3)glucanosyltransferases. The active site residues in the Aspergillus fumigatus example are the two glutamate residues at 160 and 261.
400806	Rxt3	6.80e-22	1044	1242	2	113	Histone deacetylation protein Rxt3. Rxt3 has been shown in yeast to be required for histone deacetylation.
400371	X8	3.98e-12	396	484	1	76	X8 domain. The X8 domain domain contains at least 6 conserved cysteine residues that presumably form three disulphide bridges. The domain is found in an Olive pollen allergen as well as at the C-terminus of several families of glycosyl hydrolases. This domain may be involved in carbohydrate binding. This domain is characteristic of GPI-anchored domains.
197867	X8	1.44e-06	396	489	1	79	Possibly involved in carbohydrate binding. The X8 domain, which may be involved in carbohydrate binding, is found in an Olive pollen antigen as well as at the C terminus of family 17 glycosyl hydrolases. It contains 6 conserved cysteine residues which presumably form three disulfide bridges.
282904	Herpes_BLLF1	2.25e-06	556	804	521	741	Herpes virus major outer envelope glycoprotein (BLLF1). This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CDS11918.1|CBM43|GH72	8.43e-131	39	494	11	461
CDS07484.1|CBM43|GH72	4.85e-123	40	522	13	492
BAP73894.1|CBM43|GH72	8.78e-108	50	486	27	453
QGN17770.1|CBM43|GH72	1.66e-107	50	486	27	453
BAO42507.1|CBM43|GH72	1.66e-107	50	486	27	453

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2W62_A	4.57e-91	50	467	36	458	Saccharomyces cerevisiae Gas2p in complex with laminaripentaose [Saccharomyces cerevisiae],2W63_A Saccharomyces Cerevisiae Gas2p In Complex With Laminaritriose And Laminaritetraose [Saccharomyces cerevisiae],5O9O_A Crystal structure of ScGas2 in complex with compound 7. [Saccharomyces cerevisiae S288C],5O9P_A Crystal structure of Gas2 in complex with compound 10 [Saccharomyces cerevisiae S288C],5O9Q_A Crystal structure of ScGas2 in complex with compound 6 [Saccharomyces cerevisiae S288C],5O9R_A Crystal structure of ScGas2 in complex with compound 9 [Saccharomyces cerevisiae S288C],5O9Y_A Crystal structure of ScGas2 in complex with compound 11 [Saccharomyces cerevisiae S288C],5OA2_A Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_B Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_C Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA6_A Crystal structure of ScGas2 in complex with compound 12 [Saccharomyces cerevisiae S288C]
2W61_A	1.16e-90	50	467	36	458	Saccharomyces cerevisiae Gas2p apostructure (E176Q mutant) [Saccharomyces cerevisiae]
5FIH_A	1.16e-90	50	467	36	458	SACCHAROMYCES CEREVISIAE GAS2P (E176Q MUTANT) IN COMPLEX WITH LAMINARITETRAOSE AND LAMINARIPENTAOSE [Saccharomyces cerevisiae]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|O13318|PHR2_CANAL	1.74e-106	45	508	23	471	pH-responsive protein 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PHR2 PE=2 SV=2
sp|P56092|EPD1_CANMA	2.02e-106	45	501	23	464	Protein EPD1 OS=Candida maltosa OX=5479 GN=EPD1 PE=3 SV=1
sp|O74137|EPD2_CANMA	4.13e-103	49	485	28	464	Protein EPD2 OS=Candida maltosa OX=5479 GN=EPD2 PE=3 SV=1
sp|P0C956|GEL4_ASPFU	3.48e-98	54	483	43	467	1,3-beta-glucanosyltransferase gel4 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gel4 PE=3 SV=1
sp|B0XVI5|GEL4_ASPFC	3.48e-98	54	483	43	467	1,3-beta-glucanosyltransferase gel4 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=gel4 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000052	0.000000

TMHMM  Annotations     

There is no transmembrane helices in TPX45703.1.