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CAZyme Information: TPX45369.1
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Synchytrium endobioticum | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Chytridiomycota; Chytridiomycetes; ; Synchytriaceae; Synchytrium; Synchytrium endobioticum | |||||||||||
| CAZyme ID | TPX45369.1 | |||||||||||
| CAZy Family | GH37 | |||||||||||
| CAZyme Description | unspecified product | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | ||||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH15 | 35 | 368 | 1.3e-17 | 0.850415512465374 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| 395586 | Glyco_hydro_15 | 1.11e-61 | 23 | 249 | 4 | 215 | Glycosyl hydrolases family 15. In higher organisms this family is represented by phosphorylase kinase subunits. |
| 406202 | ILEI | 2.00e-21 | 1067 | 1156 | 1 | 89 | Interleukin-like EMT inducer. ILEI is a family of proteins found in vertebrates. It is heavily involved in the process of the transition from epithelial to mesenchymal tissue - EMT - during all of embryonic development, cancer progression, metastasis, and chronic inflammation/fibrosis. ILEI is upregulated exclusively at the level of translation, and abnormal ILEI expression, ie cytoplasmic over-expression instead of vesicular localization, is associated with EMT in human cancerous tissue. In order to induce and maintain the EMT of hepatocytes in a TGF-beta-independent fashion ILEI needs the cooperation of oncogenic Ras. |
| 260114 | ILEI_FAM3C | 1.04e-20 | 1052 | 1159 | 33 | 140 | Interleukin-like EMT inducer. The secreted factor FAM3C or ILEI (InterLeukin-like Emt Inducer) has been identifed as a protein involved in the epithelial-mesenchymal transition (EMT) and in processes associated with metastasis formation and the progression of cancer. The protein had initially been predicted to be a member of the four-helical cytokine family, hence the FAM3C designation. ILEI has been found to be widely expressed, and to be involved in retinal development. |
| 260112 | PANDER_like_TMEM2 | 1.27e-20 | 1066 | 1167 | 47 | 148 | PANDER-like domain of the transmembrane protein TMEM2. TMEM2 has been characterized as a transmembrane protein that maps to the DFNB7-DFNB11 deafness locus on human chromosome 9. It contains a domain similar to the Pancreatic-derived factor PANDER, C-terminal to a glycine rich G8-domain. The function of the PANDER-like domain in TMEM2 has not been characterized. |
| 260110 | PANDER_like | 2.49e-20 | 1037 | 1180 | 5 | 149 | Domains similar to the Pancreatic-derived factor. FAM3B or PANDER (PANcreatic DERived factor) has been identifed as a regulator of glucose homeostasis and beta cell function. The protein is expressed in the endocrine pancreas and co-secreted with insulin in response to glucose, particularly under conditions of insulin resistance. The protein had initially been predicted to be a member of the four-helical cytokine family, hence the FAM3B designation. This wider family contains FAM3B and FAM4C, N-terminal domains of N-acetylglucosaminyltransferases, and domains in poorly characterized proteins that have been associated with deafness and the progression of cancer. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| 0.0 | 20 | 1156 | 15 | 1235 | |
| 1.23e-250 | 22 | 983 | 9 | 860 | |
| 1.46e-249 | 22 | 983 | 10 | 861 | |
| 2.06e-249 | 22 | 983 | 10 | 861 | |
| 2.06e-249 | 22 | 983 | 10 | 861 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1.88e-13 | 1044 | 1201 | 23 | 175 | Chain A, Protein FAM3A [Mus musculus] |
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| 2.85e-10 | 1044 | 1196 | 55 | 202 | Xray structure of human FAM3C ILEI monomer [Homo sapiens],5LC2_B Xray structure of human FAM3C ILEI monomer [Homo sapiens] |
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| 1.55e-09 | 1030 | 1156 | 26 | 150 | Long wavelength S-SAD structure of FAM3B PANDER [Mus musculus],2YOP_B Long wavelength S-SAD structure of FAM3B PANDER [Mus musculus],2YOP_C Long wavelength S-SAD structure of FAM3B PANDER [Mus musculus] |
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| 2.03e-09 | 1030 | 1156 | 42 | 166 | Structure of FAM3B PANDER E30 construct [Mus musculus],2YOQ_B Structure of FAM3B PANDER E30 construct [Mus musculus],2YOQ_C Structure of FAM3B PANDER E30 construct [Mus musculus] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7.05e-222 | 22 | 1307 | 10 | 1156 | Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Oryctolagus cuniculus OX=9986 GN=PHKA2 PE=2 SV=1 |
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| 2.13e-219 | 22 | 1303 | 10 | 1152 | Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Mus musculus OX=10090 GN=Phka2 PE=1 SV=1 |
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| 1.31e-215 | 22 | 1303 | 10 | 1152 | Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens OX=9606 GN=PHKA2 PE=1 SV=1 |
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| 1.90e-214 | 22 | 1305 | 10 | 1144 | Probable phosphorylase b kinase regulatory subunit alpha OS=Drosophila melanogaster OX=7227 GN=CG7766 PE=1 SV=2 |
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| 1.70e-210 | 22 | 1303 | 10 | 1153 | Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Oryctolagus cuniculus OX=9986 GN=PHKA1 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | CS Position |
|---|---|---|
| 0.999998 | 0.000048 |
