CAZyme Information: TPX38799.1

Basic Information

• Species: Synchytrium endobioticum
• Lineage: Chytridiomycota; Chytridiomycetes; ; Synchytriaceae; Synchytrium; Synchytrium endobioticum
• CAZyme ID: TPX38799.1
• CAZy Family: CE4
• CAZyme Description: alpha,alpha-trehalase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1306	QEAN01000378|CGC1	147415.84	5.6854

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_SendobioticumMB42	8031	N/A	0	8031

• Gene Location: location=QEAN01000378:13213-18119(-)

Full Sequence      

MIKFIHTLIYLFAVVSSVSPAPCSSPIYCYGDILETVLRHLNASVKVFVDAPSKQPLKLV
LHSFNAQAPSIKLQNHSISTFLEENFAASGSDVVHTGINYPQNPRFLTKVRDSVLLNWAR
HVHAFWPRLTKKWEGKLCDGCVTSFDTHASRPFIIPGGMFKEQYYWDTYFICEGLLVSEA
HEMIYNMVRNLLDMVAAYGFVPNGSRIYYLNRSQPPLLTLLVSKFLSNDSITADILQLLE
TELEFWTTGPKAIHFNSTNSILSLSRYYVYSDSPRPEAFKADLNVTMGSGKKQEIGIWTE
LATGAETGWDFSSRWIHTDVPVSNSSLENLRNQEPTKFIPIDLNSILLQSERALATMYEA
RGNHSRSEYYHNKAQLRQHTMQILLCTQSSHCGDLQMPGSKTGMQLRYEKYSLERYWAAW
AGGIIESCDVANEMVSLVDESLDRFPGGLPVTRVQTGLQWDFPNVWAPLQYVAIQALDQF
SSQCPNLSYQSKRASLRVAQAFITNAFCAWLSSGGNLNSALTTYSGTDTNSNGDYTGPYF
YEKYNALGFGYSGISFEYTPQIGFGWTNGVLLWMIDRYAGNLTLDASRSTVSWSRTDIHI
CFSSHSFGIRLTRENEAQTASSCVPKEFVTALKSDVSTCEPLLSWVDLRALHASQERKVA
LATTMMAKRSAVVDTDGEGEGTKRARLSTSGGSGSGSATDILFQWAINQGATLDKIYMHH
HESDPDNRSIYAKTDILPNDLIAAIPKAVILTESVVANTRLGQHLLSVIPDFNSSWSYWS
KGLMLMIGFMVYERFENPNSFWMPYLRTLPKEYNLPIAWDVELVGKELKGTNLMYFVDEK
KKELRRAFEGICNDEQVMKKWYKSGSMTWMNWLWSFCGVSSRAFPKRKFRNASGVLSMDG
AGGVGCNGLVDVSDGPHGQDGTIRDSVLGDPRVEECELAMWPVLDMLNHQRNAKIEWVTT
LAQGVSFINRQPDKIIRAHTEVFNNYGPKGNELLLGHYGFVLETNEEDYVKVRLAVEIDN
PELASANNNRTLDGKLDHLKSLNLDERQFLFFQSDKTLPVNMIRTVRILLARRCDEWKSS
DGTNTISTRNEIDVFYKSYCLLKSRQDLLVSNPLVADDDEMAERGEVRKHNEDVRKTNAR
IYRQGQRRILRHAIDLSISQCKSYLSETSLTIEYVDPLDPDANPYRLDAETLMILKIQSL
RTTNNTLKELAITRSRQLVEEVLGSDTTESASEHYQGLVQDNVVETDGLSLEDFLWCASV
LETHTLGLSREFMHLLEIDISSVDQAEGSRDEEQEEGEMEIICLAL

Enzyme Prediction     

EC	3.2.1.28:1

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH37	46	578	6.4e-115	0.9877800407331976

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
395961	Trehalase	9.92e-105	46	578	7	508	Trehalase. Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.
215307	PLN02567	1.50e-103	28	581	13	547	alpha,alpha-trehalase
224541	TreA	2.03e-66	152	578	161	552	Neutral trehalase [Carbohydrate transport and metabolism].
183936	treA	3.84e-64	13	580	33	538	alpha,alpha-trehalase TreA.
237326	treA	1.39e-61	121	576	122	534	alpha,alpha-trehalase TreA.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SMQ54948.1|GH37	5.76e-93	21	582	25	627
SMR59387.1|GH37	7.92e-93	21	582	25	627
SMR63222.1|GH37	2.83e-92	21	582	25	627
UPK93464.1|GH37	7.02e-92	21	582	29	631
CDS07813.1|GH37	7.10e-92	23	583	33	571

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7E9U_A	4.98e-58	46	586	42	564	Chain A, Trehalase [Arabidopsis thaliana],7E9U_B Chain B, Trehalase [Arabidopsis thaliana]
7E9X_A	5.51e-57	46	586	42	564	Chain A, Trehalase [Arabidopsis thaliana],7E9X_B Chain B, Trehalase [Arabidopsis thaliana],7E9X_C Chain C, Trehalase [Arabidopsis thaliana],7E9X_D Chain D, Trehalase [Arabidopsis thaliana],7EAW_A Chain A, Trehalase [Arabidopsis thaliana],7EAW_B Chain B, Trehalase [Arabidopsis thaliana]
2JG0_A	3.20e-55	121	576	88	500	Family 37 trehalase from Escherichia coli in complex with 1- thiatrehazolin [Escherichia coli K-12],2JJB_A Family 37 trehalase from Escherichia coli in complex with casuarine-6- O-alpha-glucopyranose [Escherichia coli K-12],2JJB_B Family 37 trehalase from Escherichia coli in complex with casuarine-6- O-alpha-glucopyranose [Escherichia coli K-12],2JJB_C Family 37 trehalase from Escherichia coli in complex with casuarine-6- O-alpha-glucopyranose [Escherichia coli K-12],2JJB_D Family 37 trehalase from Escherichia coli in complex with casuarine-6- O-alpha-glucopyranose [Escherichia coli K-12],2WYN_A Structure of family 37 trehalase from Escherichia coli in complex with a casuarine-6-O-a-D-glucoside analogue [Escherichia coli K-12],2WYN_B Structure of family 37 trehalase from Escherichia coli in complex with a casuarine-6-O-a-D-glucoside analogue [Escherichia coli K-12],2WYN_C Structure of family 37 trehalase from Escherichia coli in complex with a casuarine-6-O-a-D-glucoside analogue [Escherichia coli K-12],2WYN_D Structure of family 37 trehalase from Escherichia coli in complex with a casuarine-6-O-a-D-glucoside analogue [Escherichia coli K-12]
5Z66_A	1.52e-53	24	577	45	538	Structure of periplasmic trehalase from Diamondback moth gut bacteria complexed with validoxylamine [Enterobacter cloacae],5Z6H_A Structure of periplasmic trehalase from Diamondback moth gut bacteria in the apo form [Enterobacter cloacae],5Z6H_B Structure of periplasmic trehalase from Diamondback moth gut bacteria in the apo form [Enterobacter cloacae]
2JF4_A	4.80e-51	121	576	88	500	Family 37 trehalase from Escherichia coli in complex with validoxylamine [Escherichia coli K-12]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q54QZ5|TREA_DICDI	1.80e-90	23	586	49	593	Trehalase OS=Dictyostelium discoideum OX=44689 GN=treh PE=3 SV=1
sp|O43280|TREA_HUMAN	1.85e-90	20	586	25	558	Trehalase OS=Homo sapiens OX=9606 GN=TREH PE=1 SV=2
sp|P19813|TREA_RABIT	1.00e-88	20	583	25	554	Trehalase OS=Oryctolagus cuniculus OX=9986 GN=TREH PE=1 SV=1
sp|Q9JLT2|TREA_MOUSE	1.79e-88	20	583	22	552	Trehalase OS=Mus musculus OX=10090 GN=Treh PE=1 SV=1
sp|P32359|TREA_TENMO	1.08e-74	15	578	17	552	Trehalase OS=Tenebrio molitor OX=7067 PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000192	0.999797	CS pos: 20-21. Pr: 0.9770

TMHMM  Annotations     

There is no transmembrane helices in TPX38799.1.