CAZyme Information: THC88824.1

Basic Information

• Species: Aspergillus tanneri
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus tanneri
• CAZyme ID: THC88824.1
• CAZy Family: AA6
• CAZyme Description: Probable alpha/beta-glucosidase agdC [Source:UniProtKB/TrEMBL;Acc:A0A4V3UMW2]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
962		109475.97	5.9128

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AtanneriNIH1004	13590	N/A	33	13557

• Gene Location: location=SOSA01000761:351-3364(-)

Full Sequence      

MAGSRPLSLWTLLNSVLLLLGCLVIPGVSVKHENFKKCSQSGFCKRNRAFADDASAKGSS
WTSPYELDAASIHFKDGQLQGTILKSISPDQKVRLPLVVSFLDSGAARVVVDEEKRLKGE
IEFRHDSRARKQRYDEAEKWVLVGGLELSKSATLSPETEVGMTKVLYGPDNAFQAIIHHA
PFNVDFQRDGQTQVQLNRKGYLNLEHWRPKADAPAGDEQKSQEDESTWWEETFGGNTDSK
PKGPESVGLDISFPGYSHVFGIPEHADSLSLRETRGGSGNHEEPYRMYNSDVFEYELNSP
MTLYGAIPFMQAHRKDSTVGVFWLNAAETWVDIVKSIPSVNPLSLGTGSKTDTQSHWFSE
SGRIDLFVFLGPTPQDITKTYGELTGYTQLPQQFAIAYHQCRWNYVTDEDVMEVDRNFDK
YQIPYDVIWLDIEYTDDRKYFTWDPLTFPNPIGMEQQLDDSERKLVVIIDPHIKNKDQYT
ISEEMKSKNLAVLNKDGEIYDGWCWPGSSHWVDCFNPEALKWWKGLFKYDKFKGTLPNVF
IWNDMNEPSVFNGPETTMPKDNLHHGDWEHRDVHNVNGITFVNATYGALLERKKGEVRRP
FILTRSYYAGAQRMSAMWTGDNQATWEHLAISLPMVLNNGISGFPFAGADVGGFFQNPSK
ELLTRWYQTGIWYPFFRAHAHIDTRRREPYLIAEPYRSIIAQAIRLRYNLLPAWYTAFHE
ASVNGTPIVRPQYYVHPSDEAGFAIDDQLYFGSTGLLTKPVVSEGTQSVDVYIADDEKYY
DYYDYTVYQGAGKRHTVPAPIEKVPLLMQGGHIIPRKDRPRRSSGLMRWDPYTLVVVLDK
NGEADGTLYVDDGETFEFERGAYIHRRFRFQDSTLSSEDLGTKGAKTAEYLKTMSDVRVE
RVVVIDPPREWQEKTSATVIEEGTKAAFTASVEYHTQSTGKAAYAVVKKPNVGIGKTWRI
EF

Enzyme Prediction     

EC	3.2.1.20:27	3.2.1.84:26

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH31	367	814	1.2e-147	0.9953161592505855

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
395838	Glyco_hydro_31	0.0	367	814	1	442	Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.
269889	GH31_GANC_GANAB_alpha	0.0	386	855	1	467	neutral alpha-glucosidase C, neutral alpha-glucosidase AB. This subgroup includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae.
224418	YicI	5.08e-179	243	890	139	744	Alpha-glucosidase, glycosyl hydrolase family GH31 [Carbohydrate transport and metabolism].
269890	GH31_glucosidase_II_MalA	5.46e-140	386	725	1	339	Alpha-glucosidase II-like. Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized in Bacillus thermoamyloliquefaciens where it forms a homohexamer. This subgroup also includes the MalA alpha-glucosidase from Sulfolobus solfataricus and the AglA alpha-glucosidase from Picrophilus torridus. MalA is part of the carbohydrate-metabolizing machinery that allows this organism to utilize carbohydrates, such as maltose, as the sole carbon and energy source.
215408	PLN02763	1.52e-107	372	864	164	644	hydrolase, hydrolyzing O-glycosyl compounds

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
KAB8076003.1|GH31	0.0	1	962	1	965
KAE8355786.1|GH31	0.0	1	962	1	966
KAE8401395.1|GH31	0.0	1	962	1	965
KAE8308002.1|GH31	0.0	1	962	1	966
KAB8200528.1|GH31	0.0	1	962	1	966

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5DKX_A	0.0	30	962	5	950	Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495],5DKY_A Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495],5JQP_A Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495]
5DKZ_A	0.0	30	962	5	950	Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495],5DL0_A Chain A, Alpha glucosidase-like protein [Thermochaetoides thermophila DSM 1495]
7KRY_A	2.26e-254	7	961	13	941	Chain A, Neutral alpha-glucosidase AB [Mus musculus],7KRY_C Chain C, Neutral alpha-glucosidase AB [Mus musculus]
5IEF_A	1.48e-252	30	961	1	910	Murine endoplasmic reticulum alpha-glucosidase II with N-butyl-1-deoxynojirimycin [Mus musculus]
5IEG_A	1.53e-252	30	961	1	910	Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q9US55|GLU2A_SCHPO	1.97e-298	31	902	28	881	Glucosidase 2 subunit alpha OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gls2 PE=1 SV=1
sp|Q8BHN3|GANAB_MOUSE	1.84e-252	13	961	16	942	Neutral alpha-glucosidase AB OS=Mus musculus OX=10090 GN=Ganab PE=1 SV=1
sp|Q9FN05|PSL5_ARATH	9.87e-252	28	905	19	864	Probable glucan 1,3-alpha-glucosidase OS=Arabidopsis thaliana OX=3702 GN=PSL5 PE=1 SV=1
sp|Q4R4N7|GANAB_MACFA	1.90e-246	16	961	19	942	Neutral alpha-glucosidase AB OS=Macaca fascicularis OX=9541 GN=GANAB PE=2 SV=1
sp|Q14697|GANAB_HUMAN	1.07e-245	16	961	19	942	Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.001368	0.998582	CS pos: 29-30. Pr: 0.9512

TMHMM  Annotations     

Start	End
7	29