Species | Saccharomycodes ludwigii | |||||||||||
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Lineage | Ascomycota; Saccharomycetes; ; Saccharomycodaceae; Saccharomycodes; Saccharomycodes ludwigii | |||||||||||
CAZyme ID | SSD61967.1 | |||||||||||
CAZy Family | GT71 | |||||||||||
CAZyme Description | probable Dolichyl-phosphate-mannose--protein mannosyltransferase 2 | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location |
EC | 2.4.1.109:13 |
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Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT39 | 68 | 306 | 4.1e-77 | 0.9910313901345291 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
224839 | PMT1 | 0.0 | 50 | 755 | 12 | 698 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
396786 | PMT | 1.98e-91 | 66 | 310 | 1 | 245 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
406576 | PMT_4TMC | 1.22e-78 | 549 | 748 | 1 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
397103 | MIR | 5.20e-19 | 357 | 522 | 11 | 183 | MIR domain. The MIR (protein mannosyltransferase, IP3R and RyR) domain is a domain that may have a ligand transferase function. |
197746 | MIR | 1.38e-08 | 471 | 527 | 2 | 57 | Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
0.0 | 1 | 754 | 1 | 755 | |
0.0 | 1 | 754 | 1 | 755 | |
0.0 | 1 | 754 | 1 | 755 | |
0.0 | 1 | 754 | 1 | 755 | |
0.0 | 1 | 754 | 1 | 755 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
0.0 | 1 | 754 | 1 | 755 | Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_B Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303] |
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2.09e-106 | 335 | 530 | 2 | 196 | Crystal structure of the MIR domain (aa 337-532) of the S. cerevisiae mannosyltransferase Pmt2 [Saccharomyces cerevisiae] |
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1.09e-105 | 336 | 531 | 20 | 214 | Structure of the Pmt2-MIR domain with bound ligands [Saccharomyces cerevisiae] |
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9.86e-99 | 48 | 750 | 33 | 727 | Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_A Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303] |
|
3.30e-95 | 334 | 536 | 10 | 212 | Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae],6ZQQ_B Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae],6ZQQ_C Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae],6ZQQ_D Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
0.0 | 48 | 757 | 51 | 768 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PMT2 PE=1 SV=1 |
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0.0 | 1 | 754 | 1 | 755 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PMT2 PE=1 SV=2 |
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0.0 | 48 | 755 | 44 | 749 | Dolichyl-phosphate-mannose--protein mannosyltransferase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PMT3 PE=1 SV=2 |
|
3.84e-226 | 1 | 753 | 1 | 758 | Dolichyl-phosphate-mannose--protein mannosyltransferase 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PMT6 PE=1 SV=1 |
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6.03e-220 | 31 | 754 | 24 | 739 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ogm2 PE=3 SV=1 |
Other | SP_Sec_SPI | CS Position |
---|---|---|
0.999725 | 0.000301 |
Start | End |
---|---|
162 | 184 |
196 | 218 |
233 | 263 |
283 | 302 |
609 | 631 |
644 | 666 |
676 | 698 |
710 | 732 |
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