CAZyme Information: SPBR_06602-t41_1-p1

Basic Information

• Species: Sporothrix brasiliensis
• Lineage: Ascomycota; Sordariomycetes; ; Ophiostomataceae; Sporothrix; Sporothrix brasiliensis
• CAZyme ID: SPBR_06602-t41_1-p1
• CAZy Family: GH76
• CAZyme Description: glycoside hydrolase family 5

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
878	AWTV01000009|CGC5	97603.30	5.0206

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_Sbrasiliensis5110	9231	1398154	140	9091

• Gene Location: location=AWTV01000009:3802910-3805617(+)

Full Sequence      

MAPIRLIIEDGVFKDSVGRQLVLRGINVAGDAKLPSAPEMPSHIAKDFFEGDKVTFHKRP
FPKEDAHLHFSRLKKMGYNTIRYVFTWEAIEAAGPGKYDEEWIQHTVDILRIAKEYGFYV
FMDPHQDVWSRFTGGSGAPMWTLYACGLNPEKFAVTEAAIVQNTYEDVDNFPKMIWSTNY
FRLAAATMFTLFFAGRDFAPKCIIDGQNIQDYLQGHFLAAIGHLAKRIKEAGDLENDVVF
GWESLNEPSKGMIGYQDISVIPKEQALKKGTSPTIFQAMLTGMGRSVEVDVWEMGGLGPV
KSGRKLVDPGGEKAWLPADYDDSRYGWKRDPGWKLGECIWAQHGVWDASSENDVLLRKNY
FAKNPRTGETIDYPCFSDSYFMDYFRANRDIVRKYHPDAIMLLQGPTMELPPNIKGTKDD
DERMVYAPHFYDGITLMTKKWNRTWNVDVLGVLRGRYWHPAFAIRVGESAIRNCFRDQLA
AMRQEGLDRVGDHPCILTEFGIPYDMDDKHAYKTGDYSSQSAAMDANHYGVEGALMEGYT
LWVYMTENDHLRGDQWNGEDLSIVSQDDSLLPVSHRPKTIPDRATAPALRRVVTSSSIGA
GEAPTSSANLSTASTDVPNQGQPRRSDVDQDDMVNPGNIKQVLTQPSISSRPASTNGHAG
NSGNNETTANDGNTNTVGSSNSSPELSNAPGFRAAEAYVRPAPIATSGEIAEYGFNLRQA
EFNLKVYGLSDEKRLAAAKKEAATLAADTPEGEEARRERSLVGADLISLNLAPGGEAAGG
DDGNGGLLPLPTVVWLPEYHFPEDSIDVEVSAGRWEISWDAEETATLQRLRWWHPPGTQT
LKIKGRVRKYNDVEGATGREDGYYDQLSNWLEGGCSVM

Enzyme Prediction     

EC	3.2.1.21:3	3.2.1.45:1	3.2.1.104:1

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH5	15	550	2.2e-224	0.9981447124304267

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
408348	Glyco_hydro_5_C	8.59e-14	700	843	1	86	Glycoside hydrolase family 5 C-terminal domain. This is the C-terminal domain of endo-glycoceramidase II (EGC), a membrane-associated family 5 glycosidase pfam00150. The C-terminal domain assumes a beta-sandwich fold, which resembles that of many carbohydrate-binding modules.
395098	Cellulase	9.40e-05	70	127	30	88	Cellulase (glycosyl hydrolase family 5).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AEO67967.1|GH5_12	0.0	1	878	1	777
AEO60005.1|GH5_12	0.0	1	878	1	764
UPK89902.1|GH5_12	0.0	1	878	1	771
QBZ62324.1|GH5_12	0.0	1	878	1	776
UNI17456.1|GH5_12	0.0	1	878	1	769

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7LPO_A	2.17e-178	13	568	28	597	Chain A, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPO_B Chain B, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPO_C Chain C, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPO_D Chain D, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPP_A Chain A, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPP_B Chain B, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPP_C Chain C, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPP_D Chain D, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPQ_A Chain A, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPQ_B Chain B, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPQ_C Chain C, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPQ_D Chain D, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99]
2OSW_A	7.52e-12	14	292	38	259	Endo-glycoceramidase II from Rhodococcus sp. [Rhodococcus sp.],2OSW_B Endo-glycoceramidase II from Rhodococcus sp. [Rhodococcus sp.],2OYK_A Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like isofagomine complex [Rhodococcus sp.],2OYK_B Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like isofagomine complex [Rhodococcus sp.],2OYL_A Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like imidazole complex [Rhodococcus sp.],2OYL_B Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like imidazole complex [Rhodococcus sp.],2OYM_A Endo-glycoceramidase II from Rhodococcus sp.: five-membered iminocyclitol complex [Rhodococcus sp.],2OYM_B Endo-glycoceramidase II from Rhodococcus sp.: five-membered iminocyclitol complex [Rhodococcus sp.]
2OSX_A	7.52e-12	14	292	38	259	Chain A, Endoglycoceramidase II [Rhodococcus sp.]
2OSY_A	3.04e-11	14	178	38	188	Chain A, Endoglycoceramidase II [Rhodococcus sp.],2OSY_B Chain B, Endoglycoceramidase II [Rhodococcus sp.]
6JYZ_A	2.11e-10	5	252	24	227	Chain A, Putative secreted endoglycosylceramidase [Rhodococcus hoagii 103S]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|H1AE13|EGCR1_ASPFM	1.20e-317	1	878	1	759	Glucosylceramidase OS=Neosartorya fumigata OX=746128 GN=egc1 PE=1 SV=1
sp|P40566|EGH1_YEAST	3.32e-170	10	861	10	756	Ergosteryl-beta-glucosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=EGH1 PE=1 SV=1
sp|I1BTD7|EGCR1_RHIO9	7.70e-108	13	565	22	548	Glucosylceramidase OS=Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) OX=246409 GN=ERC1 PE=1 SV=1
sp|H1AE12|EGCR1_CRYNH	1.22e-75	8	566	18	558	Glucosylceramidase OS=Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) OX=235443 GN=EGC1 PE=1 SV=1
sp|Q6L6S1|EGCSE_HYDVU	9.10e-07	9	262	28	245	Endoglycoceramidase OS=Hydra vulgaris OX=6087 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000081	0.000000

TMHMM  Annotations     

There is no transmembrane helices in SPBR_06602-t41_1-p1.