CAZyme Information: SMR64677.1

Basic Information

• Species: Zymoseptoria tritici
• Lineage: Ascomycota; Dothideomycetes; ; Mycosphaerellaceae; Zymoseptoria; Zymoseptoria tritici
• CAZyme ID: SMR64677.1
• CAZy Family: GT62
• CAZyme Description: unspecified product

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
561	LT854285|CGC1	62786.48	6.7404

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_ZtriticiST99CH3D1	11991	1276537	0	11991

• Gene Location: location=LT854285:998879-1000620(-)

Full Sequence      

MPQPSSATLIRQVFNVLTTIVLCSAVAGVFVSFRFPGTWIRSGEILIAIYDRLFASRKKN
DHDPEAVILEKQTSKDTVGCAVGWREEEDIFERCLEALKASDVCAVVVGVDGDTTEDMPM
LGVFGDVFPDAPPPIHLDTPVGDALLDAESAIAANIDQLLSIVETQITTQLGIDRSQLCT
IDAICIYQPHRNKKAILLTTFLAGIVMARAKQVPFLFSCDSDTVVAPQTIDQVVASLRPR
PQAGGASGRISTWKSNQSFLCKLQSLKWWFDQDVSRTQTAATGFLECQPGPSCAFRATAL
EQVLITWYSASAWGRRCVTNEDRDLTAKLLHAGWEIYYVPHAVVWTDVPTSLAGWFKQQL
RWSRGTHFQRLSSHGLYTTMNPYFTMYVMKDMLMPFVACAYLVWFVLTGERFLRLSEYDL
AVSLLVELIYTLLTAADRIPWTDLVYLFPSYIFYSLTKPAIHIWSLFTMFNNSWGNPFDR
GARPGLTMPEYAWCGGWVYLTLAASLKALSESMNYKKRNAINETFAVVVFPSLLALGAIS
AWHLALTRPKRRWTEQVGSVV

Enzyme Prediction     

No EC number prediction in SMR64677.1.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
133056	GT2_HAS	1.70e-24	173	366	45	232	Hyaluronan synthases catalyze polymerization of hyaluronan. Hyaluronan synthases (HASs) are bi-functional glycosyltransferases that catalyze polymerization of hyaluronan. HASs transfer both GlcUA and GlcNAc in beta-(1,3) and beta-(1,4) linkages, respectively to the hyaluronan chain using UDP-GlcNAc and UDP-GlcUA as substrates. HA is made as a free glycan, not attached to a protein or lipid. HASs do not need a primer for HA synthesis; they initiate HA biosynthesis de novo with only UDP-GlcNAc, UDP-GlcUA, and Mg2+. Hyaluronan (HA) is a linear heteropolysaccharide composed of (1-3)-linked beta-D-GlcUA-beta-D-GlcNAc disaccharide repeats. It can be found in vertebrates and a few microbes and is typically on the cell surface or in the extracellular space, but is also found inside mammalian cells. Hyaluronan has several physiochemical and biological functions such as space filling, lubrication, and providing a hydrated matrix through which cells can migrate.
224136	BcsA	1.26e-19	185	470	115	390	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
133033	Chitin_synth_C	8.69e-18	191	368	55	243	C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin. Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.
236882	PRK11204	1.57e-14	194	367	122	280	N-glycosyltransferase; Provisional
133043	CESA_CelA_like	5.71e-10	290	366	162	230	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SMR64677.1|GT2	0.0	1	561	1	561
SMQ56347.1|GT2	0.0	1	561	1	561
SMY30007.1|GT2	0.0	1	561	1	561
SMR62182.1|GT2	0.0	1	561	1	561
QMW26501.1|GT2	2.50e-78	59	535	85	581

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7SP7_A	1.75e-29	83	543	91	538	Chain A, Hyaluronan synthase [Paramecium bursaria Chlorella virus CZ-2]
7SP6_A	7.69e-29	83	543	91	538	Chain A, Hyaluronan synthase [Paramecium bursaria Chlorella virus CZ-2],7SP8_A Chain A, Hyaluronan synthase [Paramecium bursaria Chlorella virus CZ-2],7SP9_A Chain A, Hyaluronan synthase [Paramecium bursaria Chlorella virus CZ-2],7SPA_A Chain A, Hyaluronan synthase [Paramecium bursaria Chlorella virus CZ-2]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|O00219|HYAS3_HUMAN	1.71e-25	80	364	90	359	Hyaluronan synthase 3 OS=Homo sapiens OX=9606 GN=HAS3 PE=1 SV=3
sp|O08650|HYAS3_MOUSE	7.42e-25	80	364	91	360	Hyaluronan synthase 3 OS=Mus musculus OX=10090 GN=Has3 PE=1 SV=2
sp|O35776|HYAS2_RAT	1.31e-24	32	364	45	356	Hyaluronan synthase 2 OS=Rattus norvegicus OX=10116 GN=Has2 PE=2 SV=1
sp|P70312|HYAS2_MOUSE	4.21e-24	32	364	45	356	Hyaluronan synthase 2 OS=Mus musculus OX=10090 GN=Has2 PE=1 SV=4
sp|G5AY81|HYAS2_HETGA	5.63e-24	32	364	45	356	Hyaluronan synthase 2 OS=Heterocephalus glaber OX=10181 GN=Has2 PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000036	0.000006

TMHMM  Annotations     

Start	End
13	35
383	405
444	466
524	546