CAZyme Information: SHO78116.1

Basic Information

• Species: Malassezia sympodialis
• Lineage: Basidiomycota; Malasseziomycetes; ; Malasseziaceae; Malassezia; Malassezia sympodialis
• CAZyme ID: SHO78116.1
• CAZy Family: GH43
• CAZyme Description: Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A1M8A6L9]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
408	LT671823|CGC8	46349.31	8.9939

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_MsympodialisATCC42132	4618	1230383	143	4475

• Gene Location: location=LT671823:1334960-1336292(-)

Full Sequence      

MMIASSPLNKLRALTGTCLFTRKGYVPVVAATLLGECILIALIIVYVPFTEIDFRTYVAQ
ARMFLEGERRYYALDPPGGSGPCVYPAGHLYIFAVLDRWTDSGAYLLPAQLAFGGLYLAT
SLVVSRIYDMVGAPPVLFLFLVLSKRLHSIYMLRMFNDPVAMLAMYICMYLLCCRKWSAA
CFAYSIALSVKMNVLLYLPGLMVVLFRAWGAWRTVVSLVIIVGGTQGLLGLPFLLHDPFA
YLKGSFDFSRVFLYEWTVNWRFLDEKTFLSASFSHLLLSLHLLLLLLFGLCQWTGISRQG
WRWISLRWCGDSVPMSPFYIIMTLATSNLIGILCARSLHYQFYSWYAHQLPLLAWTSSFS
IPVTIVAPLVLEWCWNVFPSTQQSSALMLLSHVMLLTGLWIWKPVQRY

Enzyme Prediction     

EC	2.4.1.258:10

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT58	32	385	5.5e-125	0.989010989010989

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
398745	ALG3	8.68e-154	33	385	4	358	ALG3 protein. The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man. ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SHO78116.1|GT58	9.52e-302	1	408	1	408
AXA51740.1|GT58	1.55e-171	24	400	25	401
SJX66503.1|GT58	4.81e-115	2	398	1	395
CBQ71473.1|GT58	1.82e-114	2	398	1	395
SAM86337.1|GT58	8.02e-111	20	398	15	395

PDB Hits     

SHO78116.1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q55F69|ALG3_DICDI	7.98e-88	23	406	16	428	Probable Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Dictyostelium discoideum OX=44689 GN=alg3 PE=3 SV=1
sp|Q9C1K8|ALG3_NEUCR	3.89e-84	31	407	39	431	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=alg-3 PE=3 SV=1
sp|Q92685|ALG3_HUMAN	2.15e-82	19	401	35	422	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG3 PE=1 SV=1
sp|O82244|ALG3_ARATH	4.28e-82	22	408	29	424	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Arabidopsis thaliana OX=3702 GN=ALG3 PE=1 SV=1
sp|A1CBE6|ALG3_ASPCL	7.76e-82	33	407	87	460	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=alg3 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000009	0.000027

TMHMM  Annotations     

Start	End
25	47
122	144
151	173
183	205
214	236
275	297
318	340
355	377
384	402