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CAZyme Information: RQM14821.1

You are here: Home > Sequence: RQM14821.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Peronospora effusa
Lineage Oomycota; NA; ; Peronosporaceae; Peronospora; Peronospora effusa
CAZyme ID RQM14821.1
CAZy Family GH72
CAZyme Description Glyco_18 domain-containing protein [Source:UniProtKB/TrEMBL;Acc:A0A3R7W4D5]
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
427 48015.51 5.5559
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_PeffusaR13 8603 N/A 0 8603
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.-:18

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 160 395 1.7e-32 0.6486486486486487

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
119354 GH18_chitobiase 8.15e-107 44 412 17 358
Chitobiase (also known as di-N-acetylchitobiase) is a lysosomal glycosidase that hydrolyzes the reducing-end N-acetylglucosamine from the chitobiose core of oligosaccharides during the ordered degradation of asparagine-linked glycoproteins in eukaryotes. Chitobiase can only do so if the asparagine that joins the oligosaccharide to protein is previously removed by a glycosylasparaginase. Chitobiase is therefore the final step in the lysosomal degradation of the protein/carbohydrate linkage component of asparagine-linked glycoproteins. The catalytic domain of chitobiase is an eight-stranded alpha/beta barrel fold similar to that of other family 18 glycosyl hydrolases such as hevamine and chitotriosidase.
214753 Glyco_18 1.28e-27 159 396 99 333
Glyco_18 domain.
119353 GH18_CFLE_spore_hydrolase 4.25e-21 110 392 54 300
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
395573 Glyco_hydro_18 1.12e-18 76 395 27 305
Glycosyl hydrolases family 18.
226376 YaaH 6.38e-15 169 417 209 423
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
0.0 1 427 422 848
1.23e-134 26 411 13 380
6.03e-133 43 411 3 351
4.70e-105 46 419 27 388
2.64e-76 45 412 25 363

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.14e-11 163 399 113 352
Crystal structure of Ostrinia furnacalis Group IV chitinase [Ostrinia furnacalis],6JMB_A Chain A, ofchtiv-allosamidin [Ostrinia furnacalis]
1.14e-10 163 399 113 352
Crystal structure of Ostrinia furnacalis Group IV chitinase [Ostrinia furnacalis]
3.95e-08 98 402 53 337
Chain A, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_B Chain B, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_C Chain C, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_D Chain D, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_E Chain E, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_F Chain F, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2]
6.69e-08 205 392 243 410
Chain A, Spore germination protein YaaH [Priestia megaterium QM B1551]
3.04e-06 169 392 118 352
Crystal structure of the catalytic domain of chitinase ChiL from Chitiniphilus shinanonensis (CsChiL) [Chitiniphilus shinanonensis],6KST_B Crystal structure of the catalytic domain of chitinase ChiL from Chitiniphilus shinanonensis (CsChiL) [Chitiniphilus shinanonensis],6KXL_A Crystal structure of the catalytic domain of Chitiniphilus shinanonensis chitinase ChiL (CsChiL) complexed with N,N'-diacetylchitobiose [Chitiniphilus shinanonensis],6KXL_B Crystal structure of the catalytic domain of Chitiniphilus shinanonensis chitinase ChiL (CsChiL) complexed with N,N'-diacetylchitobiose [Chitiniphilus shinanonensis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4.70e-77 45 412 25 363
Di-N-acetylchitobiase OS=Rattus norvegicus OX=10116 GN=Ctbs PE=1 SV=1
7.14e-76 45 412 24 362
Di-N-acetylchitobiase OS=Mus musculus OX=10090 GN=Ctbs PE=1 SV=2
1.01e-70 45 412 40 378
Di-N-acetylchitobiase OS=Homo sapiens OX=9606 GN=CTBS PE=1 SV=1
3.83e-58 46 424 26 382
Probable di-N-acetylchitobiase 2 OS=Dictyostelium discoideum OX=44689 GN=ctbs2 PE=3 SV=1
2.58e-48 44 419 21 373
Probable di-N-acetylchitobiase 1 OS=Dictyostelium discoideum OX=44689 GN=ctbs1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000242 0.999743 CS pos: 19-20. Pr: 0.9726

TMHMM  Annotations      help

There is no transmembrane helices in RQM14821.1.