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CAZyme Information: RL4_JR_09409-RA-p1

You are here: Home > Sequence: RL4_JR_09409-RA-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Raffaelea lauricola
Lineage Ascomycota; Sordariomycetes; ; Ophiostomataceae; Raffaelea; Raffaelea lauricola
CAZyme ID RL4_JR_09409-RA-p1
CAZy Family GT2|GT2
CAZyme Description unspecified product
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1360 JACBXF010000158|CGC1 151737.87 5.9426
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_RlauricolaRL4 10461 N/A 146 10315
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in RL4_JR_09409-RA-p1.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH128 47 273 1.6e-67 0.9776785714285714
GT2 959 1192 2.4e-50 0.9898477157360406

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
371727 Glyco_hydro_cc 5.54e-79 37 273 3 235
Glycosyl hydrolase catalytic core. This family is probably a glycosyl hydrolase, and is conserved in fungi and some Proteobacteria. The pombe member is annotated as being from IPR013781.
206738 DLP_1 1.43e-50 354 641 5 273
Dynamin_like protein family includes dynamins and Mx proteins. The dynamin family of large mechanochemical GTPases includes the classical dynamins and dynamin-like proteins (DLPs) that are found throughout the Eukarya. These proteins catalyze membrane fission during clathrin-mediated endocytosis. Dynamin consists of five domains; an N-terminal G domain that binds and hydrolyzes GTP, a middle domain (MD) involved in self-assembly and oligomerization, a pleckstrin homology (PH) domain responsible for interactions with the plasma membrane, GED, which is also involved in self-assembly, and a proline arginine rich domain (PRD) that interacts with SH3 domains on accessory proteins. To date, three vertebrate dynamin genes have been identified; dynamin 1, which is brain specific, mediates uptake of synaptic vesicles in presynaptic terminals; dynamin-2 is expressed ubiquitously and similarly participates in membrane fission; mutations in the MD, PH and GED domains of dynamin 2 have been linked to human diseases such as Charcot-Marie-Tooth peripheral neuropathy and rare forms of centronuclear myopathy. Dynamin 3 participates in megakaryocyte progenitor amplification, and is also involved in cytoplasmic enlargement and the formation of the demarcation membrane system. This family also includes interferon-induced Mx proteins that inhibit a wide range of viruses by blocking an early stage of the replication cycle. Dynamin oligomerizes into helical structures around the neck of budding vesicles in a GTP hydrolysis-dependent manner.
404513 Glyco_trans_2_3 2.81e-46 959 1193 1 194
Glycosyl transferase family group 2. Members of this family of prokaryotic proteins include putative glucosyltransferases, which are involved in bacterial capsule biosynthesis.
197491 DYNc 1.02e-17 355 595 29 239
Dynamin, GTPase. Large GTPases that mediate vesicle trafficking. Dynamin participates in the endocytic uptake of receptors, associated ligands, and plasma membrane following an exocytic event.
395279 Dynamin_N 5.97e-12 355 552 1 167
Dynamin family.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
0.0 347 1360 19 1016
0.0 347 1360 19 1034
0.0 347 1360 19 1034
0.0 460 1360 6 912
2.51e-312 762 1360 52 642

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6.40e-23 355 684 37 345
GDP-bound stalkless-MxA [Homo sapiens]
3.16e-21 355 684 37 348
Nucleotide-free stalkless-MxA [Homo sapiens]
3.30e-21 355 649 31 305
GMPPCP-bound stalkless-MxA [Homo sapiens]
5.32e-21 355 644 16 285
GMPPCP-bound stalkless-MxA [Homo sapiens]
1.20e-19 355 649 41 315
Modified human MxA, nucleotide-free form [Homo sapiens],5GTM_B Modified human MxA, nucleotide-free form [Homo sapiens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6.90e-24 25 274 294 529
Alkali-sensitive linkage protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=asl1 PE=1 SV=1
1.86e-20 355 667 37 341
Interferon-induced GTP-binding protein Mx1 OS=Ictalurus punctatus OX=7998 GN=mx1 PE=2 SV=1
5.50e-20 355 647 46 325
Interferon-induced GTP-binding protein MxC OS=Danio rerio OX=7955 GN=mxc PE=2 SV=1
1.35e-19 355 666 40 334
Interferon-induced GTP-binding protein MxA OS=Danio rerio OX=7955 GN=mxa PE=2 SV=1
1.58e-19 355 612 121 355
Interferon-induced GTP-binding protein Mx2 OS=Canis lupus familiaris OX=9615 GN=MX2 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000697 0.999281 CS pos: 16-17. Pr: 0.9452

TMHMM  Annotations      download full data without filtering help

Start End
708 730
747 769
1172 1194
1207 1229
1239 1261
1304 1326
1331 1353