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CAZyme Information: QYA_153118T0-p1

You are here: Home > Sequence: QYA_153118T0-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Mucor lusitanicus
Lineage Mucoromycota; Mucoromycetes; ; Mucoraceae; Mucor; Mucor lusitanicus
CAZyme ID QYA_153118T0-p1
CAZy Family GH5
CAZyme Description Chitin synthase [Source:UniProtKB/TrEMBL;Acc:A0A168LWF6]
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1818 McirCBS277-49_SC04|CGC15 205320.36 6.4893
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_MlusitanicusCBS277-49 11852 747725 0 11852
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.16:11

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT2 1217 1722 4.3e-239 0.9924098671726755

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
276845 MYSc_Myo17 0.0 10 730 1 647
class XVII myosin, motor domain. This fungal myosin which is also known as chitin synthase uses its motor domain to tether its vesicular cargo to peripheral actin. It works in opposition to dynein, contributing to the retention of Mcs1 vesicles at the site of cell growth and increasing vesicle fusion necessary for polarized growth. Class 17 myosins consist of a N-terminal myosin motor domain with Cyt-b5, chitin synthase 2, and a DEK_C domains at it C-terminus. The chitin synthase region contains several transmembrane domains by which myosin 17 is thought to bind secretory vesicles. The catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are actin-dependent molecular motors that play important roles in muscle contraction, cell motility, and organelle transport. The head domain is a molecular motor, which utilizes ATP hydrolysis to generate directed movement toward the plus end along actin filaments. A cyclical interaction between myosin and actin provides the driving force. Rates of ATP hydrolysis and consequently the speed of movement along actin filaments vary widely, from about 0.04 micrometer per second for myosin I to 4.5 micrometer per second for myosin II in skeletal muscle. Myosin II moves in discrete steps about 5-10 nm long and generates 1-5 piconewtons of force. Upon ATP binding, the myosin head dissociates from an actin filament. ATP hydrolysis causes the head to pivot and associate with a new actin subunit. The release of Pi causes the head to pivot and move the filament (power stroke). Release of ADP completes the cycle. CyMoBase classifications were used to confirm and identify the myosins in this hierarchy.
367353 Chitin_synth_2 0.0 1215 1722 1 526
Chitin synthase. Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They catalyze chitin synthesis as follows: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N) <=> UDP + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N+1).
214580 MYSc 8.29e-163 3 730 10 674
Myosin. Large ATPases. ATPase; molecular motor. Muscle contraction consists of a cyclical interaction between myosin and actin. The core of the myosin structure is similar in fold to that of kinesin.
276950 MYSc 1.12e-162 13 721 1 633
Myosin motor domain superfamily. Myosin motor domain. The catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are actin-dependent molecular motors that play important roles in muscle contraction, cell motility, and organelle transport. The head domain is a molecular motor, which utilizes ATP hydrolysis to generate directed movement toward the plus end along actin filaments. A cyclical interaction between myosin and actin provides the driving force. Rates of ATP hydrolysis and consequently the speed of movement along actin filaments vary widely, from about 0.04 micrometer per second for myosin I to 4.5 micrometer per second for myosin II in skeletal muscle. Myosin II moves in discrete steps about 5-10 nm long and generates 1-5 piconewtons of force. Upon ATP binding, the myosin head dissociates from an actin filament. ATP hydrolysis causes the head to pivot and associate with a new actin subunit. The release of Pi causes the head to pivot and move the filament (power stroke). Release of ADP completes the cycle. CyMoBase classifications were used to confirm and identify the myosins in this hierarchy.
395017 Myosin_head 1.29e-134 3 719 3 672
Myosin head (motor domain).

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
0.0 3 1724 13 1689
0.0 3 1748 13 1723
0.0 32 1728 53 1678
0.0 3 1730 17 1748
0.0 3 1730 17 1748

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.70e-87 3 719 73 750
Crystal Structure Of Myosin V Motor Domain - Nucleotide-Free [Gallus gallus],1W8J_B Crystal Structure Of Myosin V Motor Domain - Nucleotide-Free [Gallus gallus],1W8J_C Crystal Structure Of Myosin V Motor Domain - Nucleotide-Free [Gallus gallus],1W8J_D Crystal Structure Of Myosin V Motor Domain - Nucleotide-Free [Gallus gallus]
2.96e-87 3 719 73 750
Chain A, Unconventional myosin-Va [Gallus gallus],7PLU_A Chain A, Unconventional myosin-Va [Gallus gallus],7PLU_D Chain D, Unconventional myosin-Va [Gallus gallus],7PLV_A Chain A, Unconventional myosin-Va [Gallus gallus],7PLW_A Chain A, Unconventional myosin-Va [Gallus gallus],7PLX_A Chain A, Unconventional myosin-Va [Gallus gallus],7PLY_A Chain A, Unconventional myosin-Va [Gallus gallus],7PLZ_A Chain A, Unconventional myosin-Va [Gallus gallus],7PLZ_D Chain D, Unconventional myosin-Va [Gallus gallus],7PM0_A Chain A, Unconventional myosin-Va [Gallus gallus],7PM1_A Chain A, Unconventional myosin-Va [Gallus gallus],7PM2_A Chain A, Unconventional myosin-Va [Gallus gallus],7PM5_A Chain A, Unconventional myosin-Va [Gallus gallus],7PM6_A Chain A, Unconventional myosin-Va [Gallus gallus],7PM6_D Chain D, Unconventional myosin-Va [Gallus gallus],7PM7_A Chain A, Unconventional myosin-Va [Gallus gallus],7PM8_A Chain A, Unconventional myosin-Va [Gallus gallus],7PM9_A Chain A, Unconventional myosin-Va [Gallus gallus],7PMA_A Chain A, Unconventional myosin-Va [Gallus gallus],7PMB_A Chain A, Unconventional myosin-Va [Gallus gallus],7PMC_A Chain A, Unconventional myosin-Va [Gallus gallus],7PMD_A Chain A, Unconventional myosin-Va [Gallus gallus],7PME_A Chain A, Unconventional myosin-Va [Gallus gallus],7PME_D Chain D, Unconventional myosin-Va [Gallus gallus],7PMF_A Chain A, Unconventional myosin-Va [Gallus gallus],7PMG_A Chain A, Unconventional myosin-Va [Gallus gallus],7PMH_A Chain A, Unconventional myosin-Va [Gallus gallus],7PMI_A Chain A, Unconventional myosin-Va [Gallus gallus],7PMJ_A Chain A, Unconventional myosin-Va [Gallus gallus],7PML_A Chain A, Unconventional myosin-Va [Gallus gallus]
3.16e-87 3 719 73 750
Crystal structure of Myosin V motor with essential light chain-nucleotide-free [Gallus gallus],1W7I_A Crystal Structure Of Myosin V Motor Without nucleotide soaked in 10 mM MgADP [Gallus gallus],1W7J_A Crystal Structure Of Myosin V Motor With Essential Light Chain + ADP-BeFx - Near Rigor [Gallus gallus]
1.90e-86 3 719 121 797
Crystal structure of mouse myosin-5a in complex with calcium-bound calmodulin [Mus musculus]
1.91e-86 3 729 65 733
Rigor myosin X co-complexed with an actin filament [Homo sapiens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
0.0 4 1726 10 1752
Chitin synthase 8 OS=Ustilago maydis (strain 521 / FGSC 9021) OX=237631 GN=CHS8 PE=3 SV=1
0.0 10 1734 21 1749
Chitin synthase 5 OS=Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) OX=235443 GN=CHS5 PE=2 SV=1
6.98e-304 891 1731 67 901
Chitin synthase 6 OS=Ustilago maydis (strain 521 / FGSC 9021) OX=237631 GN=CHS6 PE=3 SV=2
2.40e-278 891 1721 160 989
Chitin synthase 4 OS=Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) OX=235443 GN=CHS4 PE=2 SV=2
3.63e-143 1242 1722 686 1183
Chitin synthase 4 OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=CHS4 PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000034 0.000000

TMHMM  Annotations      download full data without filtering help

Start End
897 914
934 956
1201 1223
1600 1622
1626 1648
1655 1677