Species | Mucor lusitanicus | |||||||||||
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Lineage | Mucoromycota; Mucoromycetes; ; Mucoraceae; Mucor; Mucor lusitanicus | |||||||||||
CAZyme ID | QYA_151941T0-p1 | |||||||||||
CAZy Family | GH47 | |||||||||||
CAZyme Description | Dolichyl-phosphate-mannose--protein mannosyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A162RI81] | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location |
EC | 2.4.1.109:13 |
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Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT39 | 73 | 311 | 3.5e-69 | 0.9910313901345291 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
224839 | PMT1 | 0.0 | 65 | 752 | 22 | 698 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
396786 | PMT | 1.25e-76 | 71 | 315 | 1 | 245 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
406576 | PMT_4TMC | 5.51e-70 | 552 | 745 | 1 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
397103 | MIR | 4.57e-31 | 361 | 523 | 11 | 180 | MIR domain. The MIR (protein mannosyltransferase, IP3R and RyR) domain is a domain that may have a ligand transferase function. |
197746 | MIR | 2.28e-10 | 411 | 467 | 1 | 57 | Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
0.0 | 1 | 751 | 1 | 753 | |
5.41e-287 | 1 | 751 | 1 | 749 | |
2.41e-275 | 72 | 749 | 100 | 779 | |
2.41e-275 | 72 | 749 | 100 | 779 | |
6.64e-275 | 72 | 749 | 99 | 778 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
1.50e-238 | 38 | 751 | 38 | 755 | Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_B Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303] |
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9.78e-110 | 51 | 728 | 34 | 705 | Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_A Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303] |
|
1.54e-57 | 339 | 536 | 1 | 196 | Crystal structure of the MIR domain (aa 337-532) of the S. cerevisiae mannosyltransferase Pmt2 [Saccharomyces cerevisiae] |
|
1.96e-57 | 337 | 536 | 16 | 213 | Structure of the Pmt2-MIR domain with bound ligands [Saccharomyces cerevisiae] |
|
4.73e-55 | 341 | 539 | 12 | 209 | Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae],6ZQQ_B Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae],6ZQQ_C Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae],6ZQQ_D Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
7.72e-238 | 38 | 751 | 38 | 755 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PMT2 PE=1 SV=2 |
|
3.28e-219 | 28 | 751 | 22 | 748 | Dolichyl-phosphate-mannose--protein mannosyltransferase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PMT3 PE=1 SV=2 |
|
8.37e-213 | 34 | 753 | 32 | 767 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PMT2 PE=1 SV=1 |
|
9.46e-207 | 72 | 749 | 63 | 737 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ogm2 PE=3 SV=1 |
|
3.19e-187 | 72 | 749 | 71 | 757 | Dolichyl-phosphate-mannose--protein mannosyltransferase 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PMT6 PE=1 SV=1 |
Other | SP_Sec_SPI | CS Position |
---|---|---|
1.000020 | 0.000011 |
Start | End |
---|---|
198 | 220 |
235 | 257 |
288 | 310 |
610 | 632 |
652 | 674 |
679 | 701 |
708 | 730 |
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