CAZyme Information: QHS74355.1

Basic Information

• Species: Saccharomyces paradoxus
• Lineage: Ascomycota; Saccharomycetes; ; Saccharomycetaceae; Saccharomyces; Saccharomyces paradoxus
• CAZyme ID: QHS74355.1
• CAZy Family: GT1
• CAZyme Description: Mns1

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
549	CP020251|CGC3	63269.68	5.1739

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_SparadoxusCBS432	5803	N/A	275	5528

• Gene Location: location=CP020251:662487-664136(+)

Full Sequence      

MKNFIGILVATVVAIIAIAYYVPRYELFERKSPEAGEMRDQIESVFLASWRDYYKHGWGY
DVYGPIEHTFHNMPRGNQPLGWIIVDSVDTLMLMYNSSTLHKSEFEAEILKSEEWINNVL
DFDIDAEVNVFETTIRMLGGLLSAYHLSDLFEVGNKTVYFNKAVDLGDRLALAFLSSQTG
IPYSSVNLRSGQGIKNHADGGASSTAEFTTLQMEFKYLAYLTGNRTYWELVERVYEPLYK
NNDLLNTYDGLVPIYTFPDTGRFGGSTIRFGSRGDSFYEYLLKQYLLTHEKLYYDLYRKS
MEGMKKYLLAQSKPSSLWYIGEREQGLQGQFSPKMDHLVCFMGGLLASGSTEGLSIQEAR
RRPFFSLFPERKSDWDLAEEITNTCYQMYNQSSSGLAPEIVVFNDGNIKQSGWWQSSLGD
FFVKPLDRHNLQRPETVESIMFMYHLSHNDKYREWGANIANSFFENTCIDCSDPKLRRFT
SLSDCITLPTKKSNNMESFWLAETLKYLYILFLDDFDLTKVVFNTEAHPFPVLDEKKMKS
QSLTTGWSL

Enzyme Prediction     

EC	3.2.1.113:99

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH47	46	532	1.2e-144	0.9955156950672646

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396217	Glyco_hydro_47	0.0	45	532	1	453	Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
240427	PTZ00470	5.62e-140	37	534	71	520	glycoside hydrolase family 47 protein; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QHS74355.1|GH47	0.0	1	549	1	549
AJR60945.1|GH47	0.0	1	549	1	549
AJR68344.1|GH47	0.0	1	549	1	549
AJP39809.1|GH47	0.0	1	549	1	549
AJR73233.1|GH47	0.0	1	549	1	549

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1DL2_A	0.0	35	549	2	511	Crystal Structure Of Class I Alpha-1,2-mannosidase From Saccharomyces Cerevisiae At 1.54 Angstrom Resolution [Saccharomyces cerevisiae]
1G6I_A	0.0	1	549	1	545	Crystal structure of the yeast alpha-1,2-mannosidase with bound 1-deoxymannojirimycin at 1.59 A resolution [Saccharomyces cerevisiae]
5KIJ_A	1.42e-92	42	532	9	451	Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase and Man9GlcNAc2-PA complex [Homo sapiens]
1FMI_A	1.69e-92	42	532	14	456	Crystal Structure Of Human Class I Alpha1,2-Mannosidase [Homo sapiens]
1FO2_A	1.79e-92	42	532	14	456	Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin [Homo sapiens],1FO3_A Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With Kifunensine [Homo sapiens]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P32906|MNS1_YEAST	0.0	1	549	1	549	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MNS1 PE=1 SV=1
sp|Q8J0Q0|MNS1_CANAX	5.99e-160	39	547	39	519	Mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Candida albicans OX=5476 GN=MNS1 PE=3 SV=2
sp|Q9P7C3|MNS1_SCHPO	3.32e-113	42	534	50	513	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC2E1P5.01c PE=1 SV=2
sp|Q93Y37|MNS3_ARATH	4.40e-105	33	532	123	620	Mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS3 OS=Arabidopsis thaliana OX=3702 GN=MNS3 PE=1 SV=1
sp|Q9UKM7|MA1B1_HUMAN	4.28e-89	42	532	253	695	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.997489	0.002546

TMHMM  Annotations     

Start	End
5	22