CAZyme Information: QEL58222.1

Basic Information

• Species: [Candida] auris
• Lineage: Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Candida; [Candida] auris
• CAZyme ID: QEL58222.1
• CAZy Family: AA2
• CAZyme Description: mannan endo-1,6-alpha-mannosidase DCW1

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
456		51234.04	4.5215

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CaurisB11245	5675	N/A	169	5506

• Gene Location: location=CP043442:555451-556821(+)

Full Sequence      

MRLLDFAITWISFASITSAVWLDTNNETTIKDATKLIAKGLLDYYQGNKYGGTIGMFSWP
YYWWHAGGAFGSLLDYSYYTQDTQYDDLIEQALTYQVGENYNYIPLNQSTTEGNDDQAFW
GFAVMAAAEHNFTNPEDPKLAWLALAQAVFNTMSSRWDMDHCNGGLRWQIFQWNSGYDYK
NSVSNGALFHMSARLARYTGNDSYVDWAEKVFDWMYGVGLLTEGEHWFVYDGTHAPDNCS
NVTKWQWTYNQGLMLAGCAYLWNYTEDEKWHNRTLNFLKSAEVFFYKKSEDAHIMYEAAC
QSPTSNQYSCNQDQRSFKAYFSRFLGLTSILVPETYDHIRRWLVDSANAAAWSCVGGSDG
HTCGLSWTNGTWDGVYGLGEQMNALEVIQNLLVAERPPPLTADTGGSSIGNPAAGYAIAK
TDAEPLDLHAKDKAGASIITAIIGVAIIGTATWLVI

Enzyme Prediction     

No EC number prediction in QEL58222.1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH76	26	402	3.6e-108	0.9664804469273743

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397638	Glyco_hydro_76	0.0	29	385	1	348	Glycosyl hydrolase family 76. Family of alpha-1,6-mannanases.
227170	COG4833	3.95e-11	58	368	42	324	Predicted alpha-1,6-mannanase, GH76 family [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QEL58222.1|GH76	0.0	1	456	1	456
QEO21536.1|GH76	0.0	1	456	1	456
QRG37305.1|GH76	0.0	1	456	1	456
QWW21472.1|GH76	0.0	1	446	1	446
QWU89693.1|GH76	0.0	1	456	1	456

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6RY0_A	3.90e-102	22	415	30	425	Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY1_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY2_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY5_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY6_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY7_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q5AD78|DCW1_CANAL	1.28e-235	13	455	12	451	Mannan endo-1,6-alpha-mannosidase DCW1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=DCW1 PE=1 SV=1
sp|P36091|DCW1_YEAST	1.65e-197	17	455	19	448	Mannan endo-1,6-alpha-mannosidase DCW1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DCW1 PE=1 SV=1
sp|Q75DG6|DCW1_ASHGO	9.25e-188	22	456	24	451	Mannan endo-1,6-alpha-mannosidase DCW1 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=DCW1 PE=3 SV=2
sp|Q6FLP9|DCW1_CANGA	1.27e-186	1	455	1	445	Mannan endo-1,6-alpha-mannosidase DCW1 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) OX=284593 GN=DCW1 PE=3 SV=1
sp|Q05031|DFG5_YEAST	1.01e-161	3	454	10	456	Mannan endo-1,6-alpha-mannosidase DFG5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DFG5 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000291	0.999699	CS pos: 19-20. Pr: 0.9754

TMHMM  Annotations     

Start	End
436	455