CAZyme Information: PWY81937.1

Basic Information

• Species: Aspergillus heteromorphus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus heteromorphus
• CAZyme ID: PWY81937.1
• CAZy Family: GH3
• CAZyme Description: chitin synthase C

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
909		102404.93	8.3676

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AheteromorphusCBS117.55	11436	1448321	306	11130

• Gene Location: location=MSFL01000013:495928-498946(+)

Full Sequence      

MRSVPRSRCPEVNPSHQQEYHPQPQHHQHGVTLRDPAEAHLARSRPSISNSSLTEEQNIY
DPSRSASSYSLDDLLTTQPASAEANLGLLSPFATPPTYQANPNPELAAGSPLLTTGADWQ
NEGWRSSQVFNPGKLQRSGTRKIRLVRGSVLSVDYPVPSAIQNSIQPIYRDAEDAFPEEF
THMRYTAATCDPDEFTLRNGYNLRPAMYNRHTELLIAITYYNEDKVLTARTLHGVMQNVR
DIVNIKKSEFWNKGGPAWQKIVVCLVFDGIDPCDKPTLDVLATVGIYQENVMKRDVDGRE
TTAHIFEYTTQLSVTPSQQLIRPGYSDDKEFPPVQMIFCLKQKNSKKINSHRWLFNAFSR
ILNPEVCILIDAGTKPGPKSLLALWEAFYNDKNLGGACGEIHAMLGPRWEKVLNPIVAAQ
NFEYKISNILDKPLESSFGYVSVLPGAFSAYRYRAIMGRPLEQYFHGDHTLSKKLGKKGI
EGMNIFKKNMFLAEDRILCFELVAKAGFKWHLSYVKASKAETDVPERAPEFISQRRRWLN
GSFAAGLYAMMHFGRIYKSSHSLPRMFFLHIQAIYTFCNTVMSWFSLSSYWLTTSVIMNL
VGTPSASNKNKGWPFGNTVTPKLNTVLQYGYLGFLALQFILALGNRPKGAKLSYTASFIY
FAIVQVYVLVLSFYLVSRAFTGGNLDFDLDHGVGAFLASFFSSASAGIVLVALVSTYGIY
WIASLLYMDPWHMLTSIWAYMAGMTSSINVLMVYAFCNWHDVSWGTKGSDKSDALPSAQT
KTQGKEQEHYIEEVDKSQADIDSQFETIVKRALEPFVEEEEDESRSLDDSYKSFRTKLVL
LWTFSNAFLAICITSEGVDKIGFTNTSTVRTSNYFRAILWATAGLSFFRFLGALYFLAKT
GVLCCISRR

Enzyme Prediction     

EC	2.4.1.16:26	2.4.1.16:26

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	220	388	7e-70	0.9938650306748467

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396286	Chitin_synth_1	1.28e-97	220	388	1	163	Chitin synthase. This region is found commonly in chitin synthases classes I, II and III. Chitin a linear homopolymer of GlcNAc residues, it is an important component of the cell wall of fungi and is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases.
133033	Chitin_synth_C	3.44e-94	216	545	1	244	C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin. Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.
400626	Chitin_synth_1N	6.49e-33	142	219	1	70	Chitin synthase N-terminal. This is the N-terminal domain of Chitin synthase (pfam01644).
224136	BcsA	3.76e-25	329	676	107	406	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
367353	Chitin_synth_2	1.46e-18	354	540	187	372	Chitin synthase. Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They catalyze chitin synthesis as follows: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N) <=> UDP + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N+1).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BAE60315.1|GT2	0.0	92	909	78	893
QMW30573.1|GT2	0.0	92	909	103	918
QMW42626.1|GT2	0.0	92	909	103	918
BAB85683.1|GT2	0.0	92	909	78	893
QRD89452.1|GT2	0.0	92	909	78	893

PDB Hits     

PWY81937.1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q92197|CHSC_ASPFU	0.0	97	909	78	893	Chitin synthase C OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chsC PE=3 SV=2
sp|P30602|CHS3_EXODE	0.0	122	865	117	864	Chitin synthase 3 OS=Exophiala dermatitidis OX=5970 GN=CHS3 PE=3 SV=2
sp|P29070|CHS1_NEUCR	0.0	108	909	110	917	Chitin synthase 1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=chs-1 PE=3 SV=2
sp|Q00757|CHSB_EMENI	0.0	122	909	126	916	Chitin synthase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chsB PE=2 SV=2
sp|P54267|CHSG_ASPFU	0.0	122	909	122	911	Chitin synthase G OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chsG PE=2 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000048	0.000000

TMHMM  Annotations     

Start	End
571	593
626	643
658	680
700	722
737	759
838	857
877	899