CAZyme Information: PWY79155.1

Basic Information

• Species: Aspergillus heteromorphus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus heteromorphus
• CAZyme ID: PWY79155.1
• CAZy Family: GH18
• CAZyme Description: putative 1,3-beta-glucanosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
527		56266.10	3.9914

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AheteromorphusCBS117.55	11436	1448321	306	11130

• Gene Location: location=MSFL01000016:144762-146616(-)

Full Sequence      

MKFSLAVGAALLGSALAVEIDPIVIKGSKFFYSSNNTQFYLRGVAYQGSTTSYTDPLADA
TTCERDIPILQEINTNVIRVYAVDPTNNHTACMNMLAEAGIYVISDLSDPTQSIDRDDPT
WETSLYTRYTDVIDDLIQYNNTLGFFAGNEVSNTVDTTDASAFVKAAVRDMKAYIKDAGY
RSVGVGYATNDDSDIRVNMADYFNCEEEDEGIDFWGYNIYSWCGASTYEESGYEERTEEF
RNYSVPVFFSEYGCNTVTPRKFTEIKALYGDNMNDVWSGGIVYMYFQTDNDYGLVSAIDS
TSVSKLTDFYYYSSEIRNATPSGTNKASYTPTNTALQTCPTVNSEWQAVASPLPPTPNAE
LCDCMNESAGCVVKASVSSDDYADLFSVVCGYTSCAGIFHNGTTGSYGAYGMCTAKQQLN
FALNKYWKEQDKADSACSFGGSATTTSTTAPTGTCKSLMSEAGTAGTGVVTSEPTAAAGS
ASASGSGVSALSSMAGASSLVVGGGGGLQFGVYVATAVVAGLGMVLL

Enzyme Prediction     

EC	2.4.1.-:3	2.4.1.-:33

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH72	19	318	4.1e-133	0.9839743589743589
CBM43	371	456	1.1e-21	0.9759036144578314

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397351	Glyco_hydro_72	3.32e-160	12	319	1	314	Glucanosyltransferase. This is a family of glycosylphosphatidylinositol-anchored beta(1-3)glucanosyltransferases. The active site residues in the Aspergillus fumigatus example are the two glutamate residues at 160 and 261.
400371	X8	1.18e-27	371	439	3	71	X8 domain. The X8 domain domain contains at least 6 conserved cysteine residues that presumably form three disulphide bridges. The domain is found in an Olive pollen allergen as well as at the C-terminus of several families of glycosyl hydrolases. This domain may be involved in carbohydrate binding. This domain is characteristic of GPI-anchored domains.
197867	X8	4.56e-13	371	441	3	69	Possibly involved in carbohydrate binding. The X8 domain, which may be involved in carbohydrate binding, is found in an Olive pollen antigen as well as at the C terminus of family 17 glycosyl hydrolases. It contains 6 conserved cysteine residues which presumably form three disulfide bridges.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCS12396.1|CBM43|GH72	7.70e-272	1	527	1	539
EAL84955.1|CBM43|GH72	6.44e-268	1	478	1	488
BAE66482.1|CBM43|GH72	1.40e-265	1	464	1	472
QMW48313.1|CBM43|GH72	1.15e-264	1	464	1	472
QRD92751.1|CBM43|GH72	1.63e-264	1	464	1	472

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2W62_A	6.48e-120	14	437	26	466	Saccharomyces cerevisiae Gas2p in complex with laminaripentaose [Saccharomyces cerevisiae],2W63_A Saccharomyces Cerevisiae Gas2p In Complex With Laminaritriose And Laminaritetraose [Saccharomyces cerevisiae],5O9O_A Crystal structure of ScGas2 in complex with compound 7. [Saccharomyces cerevisiae S288C],5O9P_A Crystal structure of Gas2 in complex with compound 10 [Saccharomyces cerevisiae S288C],5O9Q_A Crystal structure of ScGas2 in complex with compound 6 [Saccharomyces cerevisiae S288C],5O9R_A Crystal structure of ScGas2 in complex with compound 9 [Saccharomyces cerevisiae S288C],5O9Y_A Crystal structure of ScGas2 in complex with compound 11 [Saccharomyces cerevisiae S288C],5OA2_A Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_B Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_C Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA6_A Crystal structure of ScGas2 in complex with compound 12 [Saccharomyces cerevisiae S288C]
2W61_A	1.82e-119	14	437	26	466	Saccharomyces cerevisiae Gas2p apostructure (E176Q mutant) [Saccharomyces cerevisiae]
5FIH_A	1.82e-119	14	437	26	466	SACCHAROMYCES CEREVISIAE GAS2P (E176Q MUTANT) IN COMPLEX WITH LAMINARITETRAOSE AND LAMINARIPENTAOSE [Saccharomyces cerevisiae]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|D4ATC3|GAS1_ARTBC	3.27e-185	1	474	1	501	1,3-beta-glucanosyltransferase ARB_07487 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_07487 PE=1 SV=1
sp|P0C955|GEL3_ASPFU	1.03e-183	1	479	1	485	1,3-beta-glucanosyltransferase gel3 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gel3 PE=3 SV=1
sp|B0XT09|GEL3_ASPFC	2.29e-183	1	475	1	481	1,3-beta-glucanosyltransferase gel3 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=gel3 PE=1 SV=1
sp|P56092|EPD1_CANMA	3.42e-178	4	470	9	476	Protein EPD1 OS=Candida maltosa OX=5479 GN=EPD1 PE=3 SV=1
sp|P0C956|GEL4_ASPFU	4.34e-176	1	465	1	489	1,3-beta-glucanosyltransferase gel4 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gel4 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000256	0.999718	CS pos: 17-18. Pr: 0.9762

TMHMM  Annotations     

There is no transmembrane helices in PWY79155.1.