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CAZyme Information: PWY77433.1

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Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Aspergillus heteromorphus
Lineage Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus heteromorphus
CAZyme ID PWY77433.1
CAZy Family GH17
CAZyme Description Endo-beta-1,4-glucanase D [Source:UniProtKB/TrEMBL;Acc:A0A317VSX9]
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
349 36540.97 4.0393
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_AheteromorphusCBS117.55 11436 1448321 306 11130
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 1.14.99.54:5 1.14.99.56:3

CAZyme Signature Domains help

Family Start End Evalue family coverage
AA9 10 232 7.6e-71 0.9772727272727273

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
397484 Glyco_hydro_61 2.87e-99 21 237 1 211
Glycosyl hydrolase family 61. Although weak endoglucanase activity has been demonstrated in several members of this family, they lack the clustered conserved catalytic acidic amino acids present in most glycoside hydrolases. Many members of this family lack measurable cellulase activity on their own, but enhance the activity of other cellulolytic enzymes. They are therefore unlikely to be true glycoside hydrolases. The subsrate-binding surface of this family is a flat Ig-like fold.
410622 LPMO_AA9 9.63e-88 20 244 1 215
lytic polysaccharide monooxygenase (LPMO) auxiliary activity family 9 (AA9). AA9 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs) involved in the cleavage of cellulose chains with oxidation of carbons C1 and/or C4 and C6. Activities include lytic cellulose monooxygenase (C1-hydroxylating) (EC 1.14.99.54) and lytic cellulose monooxygenase (C4-dehydrogenating) (EC 1.14.99.56). The family used to be called GH61 because weak endoglucanase activity had been demonstrated in some family members.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
2.77e-192 1 349 1 402
8.55e-191 1 349 1 400
1.30e-183 1 349 1 363
2.64e-145 1 349 1 373
6.07e-141 1 348 1 338

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7.02e-125 20 242 1 223
Chain AAA, Endoglucanase, putative [Aspergillus fischeri NRRL 181],7OVA_BBB Chain BBB, Endoglucanase, putative [Aspergillus fischeri NRRL 181],7OVA_CCC Chain CCC, Endoglucanase, putative [Aspergillus fischeri NRRL 181],7OVA_DDD Chain DDD, Endoglucanase, putative [Aspergillus fischeri NRRL 181]
8.65e-125 20 249 1 230
Chain A, Lytic polysaccharide monooxygenase [Talaromyces verruculosus]
1.82e-116 21 246 2 227
Thermoascus GH61 isozyme A [Thermoascus aurantiacus],2YET_B Thermoascus GH61 isozyme A [Thermoascus aurantiacus],3ZUD_A Thermoascus Gh61 Isozyme A [Thermoascus aurantiacus],7PU1_AAA Chain AAA, Gh61 isozyme a [Thermoascus aurantiacus],7PU1_BBB Chain BBB, Gh61 isozyme a [Thermoascus aurantiacus]
3.67e-104 21 242 2 224
AFGH61B L90V/D131S/M134L/A141W VARIANT [Aspergillus fumigatus Af293],6HA5_B AFGH61B L90V/D131S/M134L/A141W VARIANT [Aspergillus fumigatus Af293]
3.43e-102 20 242 1 224
Crystal structure of an endoglucanase PMO-5 [Aspergillus fumigatus Af293],5X6A_B Crystal structure of an endoglucanase PMO-5 [Aspergillus fumigatus Af293]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4.04e-81 17 252 19 253
Endoglucanase-4 OS=Hypocrea jecorina OX=51453 GN=cel61a PE=1 SV=1
2.17e-77 11 252 11 250
Polysaccharide monooxygenase Cel61a OS=Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799) OX=573729 GN=Cel61a PE=1 SV=1
7.38e-66 17 242 17 244
Endoglucanase-7 OS=Hypocrea jecorina (strain QM6a) OX=431241 GN=cel61b PE=1 SV=3
3.90e-37 14 244 24 253
Cellulose-growth-specific protein OS=Agaricus bisporus OX=5341 GN=cel1 PE=3 SV=1
2.23e-26 58 244 39 234
Probable endo-beta-1,4-glucanase D OS=Aspergillus kawachii (strain NBRC 4308) OX=1033177 GN=eglD PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.001405 0.998570 CS pos: 19-20. Pr: 0.9609

TMHMM  Annotations      help

There is no transmembrane helices in PWY77433.1.