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CAZyme Information: PWY69453.1

You are here: Home > Sequence: PWY69453.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Aspergillus eucalypticola
Lineage Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus eucalypticola
CAZyme ID PWY69453.1
CAZy Family GH16
CAZyme Description CobW domain protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
999 MSFU01000018|CGC1 111369.24 4.3055
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_AeucalypticolaCBS122712 12207 1448314 274 11933
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.67:2

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH28 77 424 9.1e-71 0.9569230769230769

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
223597 YejR 2.73e-66 432 907 11 322
GTPase, G3E family [General function prediction only].
349766 CobW-like 2.62e-58 432 676 10 198
cobalamin synthesis protein CobW. The function of this protein family is unknown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage caused by mitomycin. YijA gene is a homologue of the CobW gene which encodes the cobalamin synthesis protein/P47K.
395231 Glyco_hydro_28 8.94e-48 94 418 14 312
Glycosyl hydrolases family 28. Glycosyl hydrolase family 28 includes polygalacturonase EC:3.2.1.15 as well as rhamnogalacturonase A(RGase A), EC:3.2.1.-. These enzymes are important in cell wall metabolism.
396860 cobW 4.25e-47 432 661 10 179
CobW/HypB/UreG, nucleotide-binding domain. This domain is found in HypB, a hydrogenase expression / formation protein, and UreG a urease accessory protein. Both these proteins contain a P-loop nucleotide binding motif. HypB has GTPase activity and is a guanine nucleotide binding protein. It is not known whether UreG binds GTP or some other nucleotide. Both enzymes are involved in nickel binding. HypB can store nickel and is required for nickel dependent hydrogenase expression. UreG is required for functional incorporation of the urease nickel metallocenter. GTP hydrolysis may required by these proteins for nickel incorporation into other nickel proteins. This family of domains also contains P47K, a Pseudomonas chlororaphis protein needed for nitrile hydratase expression, and the cobW gene product, which may be involved in cobalamin biosynthesis in Pseudomonas denitrificans.
215540 PLN03010 1.15e-30 104 425 106 391
polygalacturonase

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
2.08e-316 1 433 1 433
2.08e-316 1 433 1 433
2.21e-303 1 436 1 435
2.21e-303 1 436 1 435
1.42e-239 7 431 7 430

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.23e-49 61 436 27 387
Crystal structure of endo-xylogalacturonan hydrolase from Aspergillus tubingensis [Aspergillus tubingensis]
6.55e-23 73 410 10 332
Endopolygalacturonase from the phytopathogenic fungus Fusarium moniliforme [Fusarium verticillioides]
2.69e-22 142 427 75 342
Chain A, Endo-polygalacturonase [Evansstolkia leycettana]
1.19e-21 142 427 75 342
Chain A, endo-polygalacturonase [Evansstolkia leycettana]
1.42e-21 142 427 67 334
Chain A, Endo-polygalacturonase [Evansstolkia leycettana]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3.92e-304 1 436 1 435
Exopolygalacturonase B OS=Aspergillus niger OX=5061 GN=pgxB PE=3 SV=1
3.92e-304 1 436 1 435
Probable exopolygalacturonase B OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=pgxB PE=3 SV=1
2.53e-240 7 431 7 430
Probable exopolygalacturonase B OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) OX=332952 GN=pgxB PE=3 SV=1
3.58e-240 7 431 7 430
Probable exopolygalacturonase B OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=pgxB PE=3 SV=2
1.43e-231 9 436 3 435
Probable exopolygalacturonase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=pgxB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.003741 0.996194 CS pos: 15-16. Pr: 0.4989

TMHMM  Annotations      help

There is no transmembrane helices in PWY69453.1.