CAZyme Information: PV07_04212-t44_1-p1

Basic Information

• Species: Cladophialophora immunda
• Lineage: Ascomycota; Eurotiomycetes; ; Herpotrichiellaceae; Cladophialophora; Cladophialophora immunda
• CAZyme ID: PV07_04212-t44_1-p1
• CAZy Family: GH128
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1084	KN847041.1|CGC15	117292.62	5.2223

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CimmundaCBS83496	12879	N/A	49	12830

• Gene Location: location=KN847041.1:5833252-5836506(-)

Full Sequence      

MAASSLFPLFGLLLSLSASFASAQSGNASTTYKTRFEGVTWDAANWVLTTTNLDQGHYQS
RMVVANGYHGINVASLGPFFEVDTPVDGDNINGWPLFDRRQTFATVGGFWDSQPKTNGSN
FPWLYQYGWDTAISGIPHWSGIIADLGGNNYLAASTDDSTISNFRSSLDMKHSLMNWAFT
WSPSGYGPFNVSYQMFAHKLNINQGFVTMNITAAKATNITIANVLNGDCAVRTTPGQNGV
DSGLIFTSVQPNGIHNITAFVYAGMTNTGASVRSVQQATWHRPYVGNNASSVASALNVTL
QAGQVATFTKFVGIASTDGFLSPRPVARNAALAARQAGYAASLQTHAAEWAQQFPTTSVD
DFSFPENGTLPNDQFILEAAITAVTNPYHLLQNTISQNAINATADAGSSINSHSISVGGL
GSDSYAGQIFWDAEVWMQPGLVAAFPSAAKGIANYRVERFQQAKQNIGTAFASSKKNTKF
SSAAAIFPWTSGRFGNCTATGPCWDYEYHLNGDIGLEFINLWISSGDTALFQESLWPIYD
SVATLYSELLERNGSHWVLLNMTDPDEYANHVDNGGFTMALISTHLNYANQFRSMFDSTP
NATWTTMAQNVLIGRDQDADVTLEYTGMNGTTVVKQADVILNTYPLSFTGQNYTSNDSLS
DLDYYAAQQSVDGPAMTYAIFSIIANQISPSGCSSYTYQQYSTHPYIRGPWFQFSEQLVD
DWNENGGTHPAYPFLTGHGGALQVVLFGYLGLRFIPDFNLHIDPSLPPQVPQVRYRTFHW
YGWPISAFSNQTHTVLTRDGSLAPGEGAVPNATYATSAIPVVVGPIGSAPLATYSLLPNS
SITVPNRQIGLIPTTENNVAQCLPVSSPDDYLPGQFPLAAVDGATSTKWQPVSANKTSSI
TVAIPEGYKVTGMVLNWGQIPPYNYSVLFHNQSLANPSATTLSSNNVLEVASNQRVHISD
TYNLTALNSIEAVQDNITTFDIPATAPPVYTARFATLRIWGSLYNASVTAGNMSGDGATV
AEWSILVEGLQSPNATATGGPVRRDLGGNLKAREDFGRLDADLLMKLGHVARYMNMDGRK
MPRR

Enzyme Prediction     

EC	3.2.1.28:5	-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH65	387	754	1.5e-79	0.9811827956989247

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
224471	ATH1	1.57e-59	45	782	10	726	Trehalose and maltose hydrolase (possible phosphorylase) [Carbohydrate transport and metabolism].
397616	Glyco_hydro_65N	3.39e-33	49	317	1	240	Glycosyl hydrolase family 65, N-terminal domain. This family of glycosyl hydrolases contains vacuolar acid trehalase and maltose phosphorylase.Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. This domain is believed to be essential for catalytic activity although its precise function remains unknown.
281612	Glyco_hydro_65m	1.54e-20	386	754	3	382	Glycosyl hydrolase family 65 central catalytic domain. This family of glycosyl hydrolases contains vacuolar acid trehalase and maltose phosphorylase.Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. The central domain is the catalytic domain, which binds a phosphate ion that is proximal the the highly conserved Glu. The arrangement of the phosphate and the glutamate is thought to cause nucleophilic attack on the anomeric carbon atom. The catalytic domain also forms the majority of the dimerization interface.
237517	PRK13807	1.14e-08	137	352	85	301	maltose phosphorylase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UKZ51236.1|GH65	0.0	32	1026	51	1041
UKZ77068.1|GH65	0.0	32	1026	51	1041
UKZ88695.1|CBM32|GH65	0.0	32	1025	51	1041
QYS98630.1|CBM32|GH65	0.0	8	1026	20	1042
QMW44967.1|GH65	0.0	21	1035	38	1049

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7FE3_A	6.41e-38	155	752	94	640	Chain A, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE3_B Chain B, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE3_C Chain C, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE4_A Chain A, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE4_B Chain B, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE4_C Chain C, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101]
3WIQ_A	3.23e-15	414	782	326	722	Crystal structure of kojibiose phosphorylase complexed with kojibiose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_A Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_B Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_C Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_D Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P78617|TREA_EMENI	0.0	27	1033	45	1044	Acid trehalase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=treA PE=3 SV=1
sp|D4B5H9|ATC1_ARTBC	0.0	26	1026	47	1051	Cell wall acid trehalase ARB_03719 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_03719 PE=1 SV=1
sp|M1RNJ8|ATH1_CANGB	1.66e-116	36	934	157	1064	Periplasmic/secreted acid trehalase ATH1 OS=Candida glabrata OX=5478 GN=ATH1 PE=1 SV=1
sp|Q5AAU5|ATC1_CANAL	1.40e-114	58	927	121	964	Cell wall acid trehalase ATC1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=ATC1 PE=1 SV=2
sp|P48016|ATH1_YEAST	4.96e-112	36	953	121	1056	Periplasmic acid trehalase ATH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=ATH1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000215	0.999771	CS pos: 23-24. Pr: 0.9749

TMHMM  Annotations     

There is no transmembrane helices in PV07_04212-t44_1-p1.