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CAZyme Information: PUG3_T011563-RA-p1

You are here: Home > Sequence: PUG3_T011563-RA-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Globisporangium ultimum
Lineage Oomycota; NA; ; Pythiaceae; Globisporangium; Globisporangium ultimum
CAZyme ID PUG3_T011563-RA-p1
CAZy Family GT110
CAZyme Description Glycogenin-1
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
245 27179.96 9.1347
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_GultimumBR650 14086 1223559 0 14086
Gene Location Start: 2972; End:3851  Strand: -

Full Sequence      Download help

MTVGVRRAAY  TTLITSDAYA  MGVEALVYSL  FKARATFPLV  VLHSSQVTQP  TVAKLTRFCA60
QFQSSTWHIS  FRSVPDIGIP  DEVTDRSTVH  VPGWVNSGYT  KLHIFAMDDF  EQIVYIDADV120
IVLQNVDELF  DRSTSFAAAP  DVFPPDRFNA  GVLVIRPNKQ  LFADLLVKAK  ELKSYDGGDT180
GFLNAFFPKW  FESDAASRLP  TPGTGTPSSR  SRFCTTRRIQ  SPGRIRVARV  TWRSCGGKCT240
RNPDA245

Enzyme Prediction      help

EC 2.4.1.186:3

CAZyme Signature Domains help

Created with Snap122436496173859811012213414715917118319620822023228224GT8
Family Start End Evalue family coverage
GT8 7 191 6.4e-33 0.7626459143968871

CDD Domains      download full data without filtering help

Created with Snap12243649617385981101221341471591711831962082202329190GT8_Glycogenin9193Glyco_transf_81191PLN001767196Gnt196187GT8_GNT1
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
133018 GT8_Glycogenin 4.46e-56 9 190 2 170
Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases.
132996 Glyco_transf_8 1.93e-15 9 193 2 203
Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+.
215090 PLN00176 2.74e-13 1 191 17 227
galactinol synthase
227884 Gnt1 1.21e-12 7 196 59 261
Alpha-N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
133064 GT8_GNT1 5.29e-12 96 187 78 170
GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases.

CAZyme Hits      help

Created with Snap12243649617385981101221341471591711831962082202329200CCA19642.1|GT87200CBZ55023.1|GT89200AAI64360.1|GT89200AAH68329.1|GT89200AAH97080.1|GT8
Hit ID E-Value Query Start Query End Hit Start Hit End
CCA19642.1|GT8 5.26e-68 9 200 3 193
CBZ55023.1|GT8 3.71e-33 7 200 4 274
AAI64360.1|GT8 9.55e-29 9 200 5 184
AAH68329.1|GT8 9.55e-29 9 200 5 184
AAH97080.1|GT8 9.55e-29 9 200 5 184

PDB Hits      download full data without filtering help

Created with Snap122436496173859811012213414715917118319620822023212006MW5_A92003T7M_A92006EQJ_A92003Q4S_A92003RMV_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
6MW5_A 2.66e-136 1 200 1 200
UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Platinum [Globisporangium ultimum],6MW8_A UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Manganese [Globisporangium ultimum]
3T7M_A 7.04e-29 9 200 6 185
Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a triclinic closed form [Homo sapiens],3T7M_B Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a triclinic closed form [Homo sapiens],3T7N_A Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a monoclinic closed form [Homo sapiens],3T7N_B Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a monoclinic closed form [Homo sapiens],3T7O_A Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP-Glucose and glucose [Homo sapiens],3T7O_B Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP-Glucose and glucose [Homo sapiens],3U2U_A Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltotetraose [Homo sapiens],3U2U_B Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltotetraose [Homo sapiens],3U2V_A Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltohexaose [Homo sapiens],3U2V_B Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltohexaose [Homo sapiens],3U2X_A Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and 1'-deoxyglucose [Homo sapiens],3U2X_B Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and 1'-deoxyglucose [Homo sapiens]
6EQJ_A 7.04e-29 9 200 6 185
Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant, apo form [Homo sapiens],6EQL_A Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant complexed with manganese and UDP [Homo sapiens],6EQL_B Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant complexed with manganese and UDP [Homo sapiens]
3Q4S_A 7.04e-29 9 200 6 185
Crystal Structure of Human Glycogenin-1 (GYG1), apo form [Homo sapiens],3QVB_A Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP [Homo sapiens],3U2W_A Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and glucose or a glucal species [Homo sapiens],3U2W_B Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and glucose or a glucal species [Homo sapiens]
3RMV_A 9.86e-29 9 200 6 185
Crystal Structure of Human Glycogenin-1 (GYG1) T83M mutant complexed with manganese and UDP [Homo sapiens],3RMW_A Crystal Structure of Human Glycogenin-1 (GYG1) T83M mutant complexed with manganese and UDP-glucose [Homo sapiens]

Swiss-Prot Hits      download full data without filtering help

Created with Snap12243649617385981101221341471591711831962082202329200sp|P46976|GLYG_HUMAN9200sp|H2KYQ5|GYG1_CAEEL9200sp|Q9R062|GLYG_MOUSE9200sp|O08730|GLYG_RAT9200sp|O15488|GLYG2_HUMAN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
sp|P46976|GLYG_HUMAN 1.81e-27 9 200 5 184
Glycogenin-1 OS=Homo sapiens OX=9606 GN=GYG1 PE=1 SV=4
sp|H2KYQ5|GYG1_CAEEL 1.32e-26 9 200 4 183
Glycogenin-1 OS=Caenorhabditis elegans OX=6239 GN=gyg-1 PE=1 SV=1
sp|Q9R062|GLYG_MOUSE 1.94e-26 9 200 5 184
Glycogenin-1 OS=Mus musculus OX=10090 GN=Gyg1 PE=1 SV=3
sp|O08730|GLYG_RAT 2.70e-26 9 200 5 184
Glycogenin-1 OS=Rattus norvegicus OX=10116 GN=Gyg1 PE=2 SV=4
sp|O15488|GLYG2_HUMAN 8.35e-26 9 200 38 217
Glycogenin-2 OS=Homo sapiens OX=9606 GN=GYG2 PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000049 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in PUG3_T011563-RA-p1.