logo
sublogo
You are browsing environment: FUNGIDB
help

CAZyme Information: PSURA_94521T0-p1

You are here: Home > Sequence: PSURA_94521T0-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phytophthora ramorum
Lineage Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora ramorum
CAZyme ID PSURA_94521T0-p1
CAZy Family PL3
CAZyme Description Translation initiation factor 2C (eIF-2C) and related proteins
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1854 203447.42 4.8114
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_PramorumPr-102 15743 N/A 251 15492
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.21:2 3.2.1.23:1 3.2.1.38:1 3.2.1.-:1

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH1 31 500 2.3e-133 0.9813519813519813

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
240015 Piwi_ago-like 1.02e-169 1394 1818 1 426
Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the 5' anchoring of the guide RNA and the other, the catalytic site for slicing.
395176 Glyco_hydro_1 2.76e-135 32 502 5 451
Glycosyl hydrolase family 1.
215631 PLN03202 2.15e-127 965 1853 36 899
protein argonaute; Provisional
225343 BglB 1.88e-108 32 505 4 456
Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism].
396649 Piwi 6.95e-101 1520 1819 1 296
Piwi domain. This domain is found in the protein Piwi and its relatives. The function of this domain is the dsRNA guided hydrolysis of ssRNA. Determination of the crystal structure of Argonaute reveals that PIWI is an RNase H domain, and identifies Argonaute as Slicer, the enzyme that cleaves mRNA in the RNAi RISC complex. In addition, Mg+2 dependence and production of 3'-OH and 5' phosphate products are shared characteristics of RNaseH and RISC. The PIWI domain core has a tertiary structure belonging to the RNase H family of enzymes. RNase H fold proteins all have a five-stranded mixed beta-sheet surrounded by helices. By analogy to RNase H enzymes which cleave single-stranded RNA guided by the DNA strand in an RNA/DNA hybrid, the PIWI domain can be inferred to cleave single-stranded RNA, for example mRNA, guided by double stranded siRNA.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
2.28e-205 23 504 23 515
7.74e-204 28 504 9 496
1.00e-203 81 537 6 451
9.87e-191 30 505 21 507
1.30e-95 30 495 2 449

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.28e-141 1052 1853 62 860
Human Argonaute-2 - miR-20a complex [Homo sapiens]
1.66e-141 1052 1853 60 858
Human Argonaute2 A481T Mutant Bound to t1-A Target RNA [Homo sapiens],4Z4I_A Human Argonaute2 A481T Mutant Bound to t1-G Target RNA [Homo sapiens]
1.66e-141 1052 1853 60 858
Crystal Structure of Human Argonaute2 [Homo sapiens],4OLB_A Crystal Structure of Human Argonaute2 Bound to Tryptophan [Homo sapiens],4W5N_A The Crystal Structure of Human Argonaute2 Bound to a Defined Guide RNA [Homo sapiens],4W5O_A The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-9 [Homo sapiens],4W5Q_A The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8 [Homo sapiens],4W5R_A The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8 (Long Target) [Homo sapiens],4W5T_A The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-7 [Homo sapiens],4Z4C_A Human Argonaute2 Bound to t1-C Target RNA [Homo sapiens],4Z4D_A Human Argonaute2 Bound to t1-G Target RNA [Homo sapiens],4Z4E_A Human Argonaute2 Bound to t1-U Target RNA [Homo sapiens],4Z4F_A Human Argonaute2 Bound to t1-DAP Target RNA [Homo sapiens],4Z4G_A Human Argonaute2 Bound to t1-Inosine Target RNA [Homo sapiens],5JS1_A Human Argonaute2 Bound to an siRNA [Homo sapiens],5JS2_A Human Argonaute-2 Bound to a Modified siRNA [Homo sapiens],5KI6_A Human Argonaute-2 bound to a guide RNA with a nucleobase modification at position 1 [Homo sapiens],6CBD_A Crystal Structure of Human Argonaute2 Bound to Three Tryptophans [Homo sapiens]
3.42e-141 1060 1853 61 861
Human Argonaute3 bound to guide RNA [Homo sapiens],5VM9_C Human Argonaute3 bound to guide RNA [Homo sapiens]
5.98e-141 1052 1853 60 858
Chain A, Protein argonaute-2 [Homo sapiens],7KI3_D Chain D, Protein argonaute-2 [Homo sapiens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6.77e-143 1061 1818 167 940
Protein argonaute PNH1 OS=Oryza sativa subsp. japonica OX=39947 GN=PHN1 PE=2 SV=1
6.21e-141 1052 1853 60 858
Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3
6.39e-141 1052 1853 61 859
Protein argonaute-2 OS=Mus musculus OX=10090 GN=Ago2 PE=1 SV=3
8.79e-141 1060 1853 59 859
Protein argonaute-3 OS=Mus musculus OX=10090 GN=Ago3 PE=2 SV=2
1.67e-140 1060 1853 59 859
Protein argonaute-3 OS=Homo sapiens OX=9606 GN=AGO3 PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000321 0.999640 CS pos: 25-26. Pr: 0.9670

TMHMM  Annotations      help

There is no transmembrane helices in PSURA_94521T0-p1.