CAZyme Information: PPTG_09237-t26_1-p1

Basic Information

• Species: Phytophthora parasitica
• Lineage: Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora parasitica
• CAZyme ID: PPTG_09237-t26_1-p1
• CAZy Family: GH28
• CAZyme Description: trehalose-phosphatase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1259	KI669577|CGC2	138330.20	5.9266

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PparasiticaINRA-310	23240	761204	119	23121

• Gene Location: location=KI669577:689451-693230(+)

Full Sequence      

MGEEVTSLHAAAASPPTSGVLSPRNEFFVSQRAATDFELSRLDTLSLEEQEILANIQDLQ
LQLMQLRADQEEDSDEDSTDKPLGASGNQLIVVSNNLPVLLERQPQTGRWKATKTTGGLD
KLMCLTGVRAEMNFLWVGWVGQHIPKSEHEAVRRLLLQHNCLPVFLSSDVASRHTGFSSE
VLWSLFHYVSEPVPFTFNAGSSSSFHSTKRFNKQDWRAYESANESFADAIAEIYNEGDSV
WVHDYHLMLLPSLLRQRIPPCRIGWFLHTPFPASDVYCRLPVRSQLLAGVLQADLVGFQT
FDYERHFLSTCHRLLGVECSHKGVRSVLPDRDHFTSIGVFPIGISLEPFARAASSMPTLN
RVNELHDKFGGKRIILGIDRLDNIKGIPHKMLAMEMLLDRFPEWQHNVVLVQIGISSRSG
VVDSKSTGANGAGENTRRPSASSASGDSSNILPRSSSYPIVKPKSSTGSDSPIKSLSESP
PRAPSPMAGGKGNIGYDPCHQLEMSSDSYHNIVTQVNQIVGRINGIFGTLDYAPIHFIQQ
QATPHEELCALYDLADVCLVTSTRDGMNLVSHEFIVCQQHFMRSKDERKKAARAAARGLS
NSGIGTEGAATPVPSHQKNIESINTAEGLAKGGVLSPIPSPRQSSASLLTDWEGEDGGPG
VLVVSEFAGCSQSLSGAIVVNPWNIEDVALSIHQALSMCRTEREIRQQKLYRYVSSNTAT
AWGEQFLEELSEAVEKNRKSSTQLPKLDKKSIVQAYRSAQNRVIILDYDRTLTPQHSLLP
LAAVGPNFKSLLDALSADERNTVFIVSGRERKFLETWLNGVRVGVAAEDGFFYRMNLSNT
REHWKTMSKFQYDVATARSGGSTATMTGMGSVSGSLDASYSSDAHSMMHMSMGSLPAYSR
HTSVPGSTDTGDNTPVAGSIAPTDDSFGGDDMSWKDLVLPTMLMFTDRTPGSYIEDKESS
LTWHYGDADPHFGSWQAKDLQIILERQLIGTALEVYQGHMSVSVEHEGCTKTRVLEGILK
HLSLPDQIAKKNDQEVDFVLCVCDDVTDDQMFQTLNALVAESNERHDERKRKEEEQAENE
RIRRDSIALSNPEPPQLHAQPVPSAAHVSKAKPRMPRPRGGNDATDELEPTIKLKGGARK
RHENEQLIGAAAAAVRGHDEYSTDDDDELDAGNYMDDDNKVAFSRLQKVPVRLAENVEIF
AVIVGPDVQHSGGRHACSFAVDTLADVRKVLKAFVDESRKGRNAADASPGDANATSPPP

Enzyme Prediction     

EC	2.4.1.15:146

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT20	87	424	6.8e-108	0.6694736842105263

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
184712	PRK14501	0.0	90	1055	3	690	putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional
340820	GT20_TPS	8.32e-173	89	730	1	462	trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.
215556	PLN03064	3.95e-166	89	1042	95	796	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional
395781	Glyco_transf_20	6.02e-164	90	732	3	470	Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex,.
215555	PLN03063	7.01e-158	89	1042	12	706	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ29831.1|GT20	0.0	1	1257	1	1234
CCA23376.1|GT20	0.0	17	1238	474	1629
CCA20339.1|GT20	1.67e-182	16	1052	15	795
CCA16456.1|GT20	1.32e-179	45	1052	127	878
QOX06485.1|GT20	6.05e-166	49	1059	19	781

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5HVO_A	1.47e-107	84	730	6	474	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_C Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_D Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
5HVM_A	8.44e-107	89	731	13	475	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVM_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
6JBI_A	1.81e-106	89	731	1	463	Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBI_B Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBR_A Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_B Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_D Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_F Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_H Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_K Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_M Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_O Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBW_A Structure of Tps1/UDP complex [Pyricularia oryzae 70-15],6JBW_B Structure of Tps1/UDP complex [Pyricularia oryzae 70-15]
5HUT_A	1.00e-105	89	730	5	467	Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUT_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUU_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HUU_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HVL_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314],5HVL_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314]
5HUV_A	3.70e-105	89	730	5	467	Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314],5HUV_B Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q54K57|TPSA_DICDI	7.82e-149	84	985	13	644	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] A OS=Dictyostelium discoideum OX=44689 GN=tpsA PE=2 SV=1
sp|Q9SYM4|TPS1_ARATH	4.71e-127	89	1042	93	794	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1 OS=Arabidopsis thaliana OX=3702 GN=TPS1 PE=1 SV=1
sp|Q9LMI0|TPS7_ARATH	9.71e-123	78	1055	49	789	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 7 OS=Arabidopsis thaliana OX=3702 GN=TPS7 PE=1 SV=1
sp|Q0WUI9|TPS8_ARATH	1.10e-122	73	1059	39	794	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8 OS=Arabidopsis thaliana OX=3702 GN=TPS8 PE=2 SV=1
sp|O80738|TPS10_ARATH	8.92e-122	91	1060	62	800	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 10 OS=Arabidopsis thaliana OX=3702 GN=TPS10 PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000046	0.000000

TMHMM  Annotations     

There is no transmembrane helices in PPTG_09237-t26_1-p1.