CAZyme Information: PPTG_04233-t26_3-p1

Basic Information

• Species: Phytophthora parasitica
• Lineage: Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora parasitica
• CAZyme ID: PPTG_04233-t26_3-p1
• CAZy Family: CBM9
• CAZyme Description: hypothetical protein, variant 1

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1582		178068.80	4.8963

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PparasiticaINRA-310	23240	761204	119	23121

• Gene Location: location=KI669566:1690669-1695481(-)

Full Sequence      

MGNDVDALGTLAVTVAESIAAGSKNVLELMLATRTYSVQVEMFRQLGLDSGVRPCGEDAD
TWAVFYNEPHCVESVACSVDELEAILRGKKKQQNKDQTCVAAGVNDIELQVDHKYPFIAS
DSEKTPMSAILYGLVGTEKFHAFHKKLVKQAQNNNIQYMVRHYPRDSPLDTLLQGYGVAL
DIKNMEYKTIDDSKKTGGDDTANDEEGAEEEDEEEEEIDDEEVDGFLFKPLMARHGAIAD
DLKQFYDILVKKADGEQEQELKAWHLKDLGASAVRAIVDAKNPLKRLETLSQDFPVQAKK
LAFSRKSISTELREEIALTRMQAANRRLKNKFIMNGIAVDPTERSFNVFDFMKTLKEEWS
VAKQLGGLPLNQSELEDMLKHVRETNQEQPVVRIHVHGSMGGSTPLYLNNIETDPNSADW
SPDLNILRRPAWNLIFVRKNMYECVLVMDPLTGAGRAALSHIGFMRMRGAPVQWALLVSS
KELMASKTSDERQAVVEKYKAFKTTDKASPWHFAKLLMLAQSKDNAEAAVKDDETNNSQS
GDEETTEVEKEENRITPTRVASGFLQRVGEDGSSDVLVERLVEAYAEAAGGVGTVEDNEE
EALECLNSDQFDDEILAMTEFIHLKHLPLDSFVFNGVVQKDLDIQRSMMANFGRDQPLYV
NMAHRGMLNGEMDLIEELLAEQDAYPAYLSIFESSEGRPGDMEVKTPSHLVADDVDGRLE
AAARPAVSYLHAPGSRALPKKQTVIFPVDLNDPRDAGHAYRVVKAVLEDSEQSLRVGVVA
QLNDSDRNTVGELAAAIIAAIGHSDNEVHLKFVLEALNCIVKQKSVNTMKDKLRGIWNKT
SKSENDKDPIYEKVLKLLSSKTGKWLTTKQRGVLTQFNTLLRSRFPPSYAHESEEDSSKI
ALPHLFINGRQVVLPPQSLSDEDVATIVNFDLKYRTQPVAKALIKRSATLKARDADKLSF
AIMKTTGIVDKYVKTDRTPQMNVEENSLNTVRLPGDPSLQVAAYVDPLSESAQVMSSLLR
MLHSQLNATIELVLLPADEYTEFPLQRFYRYLFDKKSSLAATSVEFRKLPVQPILTMKID
TPEAWNVQAFHAGDDLDNLRVDPDSPAAAKSTTSAVFQLESLLVYGQCRDTTFNMYSPPN
GLQLVLEREVGAQLLHRDTLVMKNLGYFQLQATPGVWSLHLARGRAAELYDIIDLDTELP
LETHPITVYDFGSHISQLYVRKKEGMEHEELLQSVEDAASEKSKSESSASEDDGALRSYW
SSMLNMMGKQDDKKIQDAVTEAEQADNDSAVVQHKERTGETIHVFSVASGYLYERFVKIM
MSSVLKRTNNPVTFWLLENFLSPDFKKSIPVLREELGMDIRLVTYKWPNWLRQQTEKQRI
IWGYKILFLDVLFPLGVQKIIYVDADQVVRADLKELWELDLQGKPYGYTPFCDSRNVGFQ
FWRQGYWKDHLRGKPYHISALYVVDLALFRQMAAGDMLRAVYSQLSADPNSLANLDQDLP
NYAQHQIPIFSLPQEWLWCESWCSDDTKVAAKTIDLCNNPKHKEPKLDMAKRVIAGELFN
ESWIELDQEIKDAEAKYAAQAA

Enzyme Prediction     

EC	2.4.1.-:29

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT24	1302	1547	5e-122	0.9959677419354839

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
408203	Glyco_transf_24	0.0	1302	1572	1	267	Glucosyltransferase 24. This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
133054	GT8_HUGT1_C_like	1.17e-161	1302	1547	1	248	The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
132996	Glyco_transf_8	1.00e-57	1302	1542	1	243	Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+.
399437	UDP-g_GGTase	5.38e-28	1126	1233	2	109	UDP-glucose:Glycoprotein Glucosyltransferase. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.
408199	Thioredoxin_12	1.45e-26	11	168	46	182	Thioredoxin-like domain. This is one of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ20865.1|GT24	0.0	3	1582	78	1665
CCA14500.1|GT24	0.0	5	1579	126	1667
AIG56125.1|GT24	0.0	10	1579	83	1507
AIG55512.1|GT24	0.0	25	1578	99	1516
CAB4116261.1|GT24	8.16e-199	25	1581	106	1563

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MU1_A	8.66e-148	130	1572	164	1446	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5MZO_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TRF_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5NV4_A	1.19e-147	130	1572	164	1446	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TRT_A	1.64e-147	130	1572	164	1446	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS2_A	9.38e-142	737	1572	397	1212	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_C Chain C, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_D Chain D, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS8_A	1.30e-121	130	1509	157	1382	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS8_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q0WL80|UGGG_ARATH	1.63e-184	31	1576	109	1571	UDP-glucose:glycoprotein glucosyltransferase OS=Arabidopsis thaliana OX=3702 GN=UGGT PE=1 SV=1
sp|Q6P5E4|UGGG1_MOUSE	1.57e-175	24	1577	115	1527	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Uggt1 PE=1 SV=4
sp|Q9NYU1|UGGG2_HUMAN	2.04e-174	25	1571	104	1496	UDP-glucose:glycoprotein glucosyltransferase 2 OS=Homo sapiens OX=9606 GN=UGGT2 PE=1 SV=4
sp|Q9NYU2|UGGG1_HUMAN	8.36e-173	24	1577	115	1527	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3
sp|Q9JLA3|UGGG1_RAT	2.85e-172	24	1577	115	1527	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Uggt1 PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000083	0.000000

TMHMM  Annotations     

There is no transmembrane helices in PPTG_04233-t26_3-p1.