CAZyme Information: PPTG_04233-t26_1-p1

Basic Information

• Species: Phytophthora parasitica
• Lineage: Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora parasitica
• CAZyme ID: PPTG_04233-t26_1-p1
• CAZy Family: CBM48
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1657	KI669566|CGC4	186489.36	4.8499

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PparasiticaINRA-310	23240	761204	119	23121

• Gene Location: location=KI669566:1690669-1695776(-)

Full Sequence      

MRPTTWLSAGLAALLAAAQPSLTSARGVHVNLTASWPSSPFFPLMETSEFLAEENPLYFW
QFLEELETRTAYVEFMGNDVDALGTLAVTVAESIAAGSKNVLELMLATRTYSVQVEMFRQ
LGLDSGVRPCGEDADTWAVFYNEPHCVESVACSVDELEAILRGKKKQQNKDQTCVAAGVN
DIELQVDHKYPFIASDSEKTPMSAILYGLVGTEKFHAFHKKLVKQAQNNNIQYMVRHYPR
DSPLDTLLQGYGVALDIKNMEYKTIDDSKKTGGDDTANDEEGAEEEDEEEEEIDDEEVDG
FLFKPLMARHGAIADDLKQFYDILVKKADGEQEQELKAWHLKDLGASAVRAIVDAKNPLK
RLETLSQDFPVQAKKLAFSRKSISTELREEIALTRMQAANRRLKNKFIMNGIAVDPTERS
FNVFDFMKTLKEEWSVAKQLGGLPLNQSELEDMLKHVRETNQEQPVVRIHVHGSMGGSTP
LYLNNIETDPNSADWSPDLNILRRPAWNLIFVRKNMYECVLVMDPLTGAGRAALSHIGFM
RMRGAPVQWALLVSSKELMASKTSDERQAVVEKYKAFKTTDKASPWHFAKLLMLAQSKDN
AEAAVKDDETNNSQSGDEETTEVEKEENRITPTRVASGFLQRVGEDGSSDVLVERLVEAY
AEAAGGVGTVEDNEEEALECLNSDQFDDEILAMTEFIHLKHLPLDSFVFNGVVQKDLDIQ
RSMMANFGRDQPLYVNMAHRGMLNGEMDLIEELLAEQDAYPAYLSIFESSEGRPGDMEVK
TPSHLVADDVDGRLEAAARPAVSYLHAPGSRALPKKQTVIFPVDLNDPRDAGHAYRVVKA
VLEDSEQSLRVGVVAQLNDSDRNTVGELAAAIIAAIGHSDNEVHLKFVLEALNCIVKQKS
VNTMKDKLRGIWNKTSKSENDKDPIYEKVLKLLSSKTGKWLTTKQRGVLTQFNTLLRSRF
PPSYAHESEEDSSKIALPHLFINGRQVVLPPQSLSDEDVATIVNFDLKYRTQPVAKALIK
RSATLKARDADKLSFAIMKTTGIVDKYVKTDRTPQMNVEENSLNTVRLPGDPSLQVAAYV
DPLSESAQVMSSLLRMLHSQLNATIELVLLPADEYTEFPLQRFYRYLFDKKSSLAATSVE
FRKLPVQPILTMKIDTPEAWNVQAFHAGDDLDNLRVDPDSPAAAKSTTSAVFQLESLLVY
GQCRDTTFNMYSPPNGLQLVLEREVGAQLLHRDTLVMKNLGYFQLQATPGVWSLHLARGR
AAELYDIIDLDTELPLETHPITVYDFGSHISQLYVRKKEGMEHEELLQSVEDAASEKSKS
ESSASEDDGALRSYWSSMLNMMGKQDDKKIQDAVTEAEQADNDSAVVQHKERTGETIHVF
SVASGYLYERFVKIMMSSVLKRTNNPVTFWLLENFLSPDFKKSIPVLREELGMDIRLVTY
KWPNWLRQQTEKQRIIWGYKILFLDVLFPLGVQKIIYVDADQVVRADLKELWELDLQGKP
YGYTPFCDSRNVGFQFWRQGYWKDHLRGKPYHISALYVVDLALFRQMAAGDMLRAVYSQL
SADPNSLANLDQDLPNYAQHQIPIFSLPQEWLWCESWCSDDTKVAAKTIDLCNNPKHKEP
KLDMAKRVIAGELFNESWIELDQEIKDAEAKYAAQAA

Enzyme Prediction     

EC	2.4.1.-:29

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT24	1377	1622	5.3e-122	0.9959677419354839

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
408203	Glyco_transf_24	0.0	1377	1647	1	267	Glucosyltransferase 24. This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
133054	GT8_HUGT1_C_like	8.06e-161	1377	1622	1	248	The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
132996	Glyco_transf_8	1.43e-57	1377	1617	1	243	Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+.
408199	Thioredoxin_12	1.40e-35	38	243	1	182	Thioredoxin-like domain. This is one of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
399437	UDP-g_GGTase	5.64e-28	1201	1308	2	109	UDP-glucose:Glycoprotein Glucosyltransferase. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ20865.1|GT24	0.0	1	1657	1	1665
CCA14500.1|GT24	0.0	26	1654	36	1667
AIG56125.1|GT24	0.0	11	1654	11	1507
AIG55512.1|GT24	0.0	21	1653	19	1516
CAB4116261.1|GT24	5.62e-204	26	1656	34	1563

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MU1_A	2.78e-147	205	1647	164	1446	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5MZO_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TRF_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5NV4_A	3.82e-147	205	1647	164	1446	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TRT_A	5.25e-147	205	1647	164	1446	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS2_A	2.73e-141	812	1647	397	1212	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_C Chain C, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_D Chain D, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS8_A	2.90e-121	205	1584	157	1382	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS8_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q0WL80|UGGG_ARATH	4.25e-190	26	1651	31	1571	UDP-glucose:glycoprotein glucosyltransferase OS=Arabidopsis thaliana OX=3702 GN=UGGT PE=1 SV=1
sp|Q9NYU1|UGGG2_HUMAN	1.98e-185	21	1646	28	1496	UDP-glucose:glycoprotein glucosyltransferase 2 OS=Homo sapiens OX=9606 GN=UGGT2 PE=1 SV=4
sp|Q6P5E4|UGGG1_MOUSE	5.72e-184	2	1652	16	1527	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Uggt1 PE=1 SV=4
sp|Q9NYU2|UGGG1_HUMAN	2.24e-181	26	1652	45	1527	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3
sp|Q9JLA3|UGGG1_RAT	2.00e-179	24	1652	43	1527	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Uggt1 PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000250	0.999718	CS pos: 25-26. Pr: 0.9503

TMHMM  Annotations     

There is no transmembrane helices in PPTG_04233-t26_1-p1.