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CAZyme Information: PPTG_04136-t26_2-p1

You are here: Home > Sequence: PPTG_04136-t26_2-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phytophthora parasitica
Lineage Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora parasitica
CAZyme ID PPTG_04136-t26_2-p1
CAZy Family CBM47
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
356 40335.39 7.2466
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_PparasiticaINRA-310 23240 761204 119 23121
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.-:5

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT7 52 297 7.1e-58 0.916

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
132999 b4GalT 8.29e-58 65 283 3 206
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids. Beta-4-Galactosyltransferase transfers galactose from uridine diphosphogalactose to the terminal beta-N-acetylglucosamine residues, hereby forming the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids. At least seven homologous beta-4-galactosyltransferase isoforms have been identified that use different types of glycoproteins and glycolipids as substrates. Of the seven identified members of the beta-1,4-galactosyltransferase subfamily (beta1,4-Gal-T1 to -T7), b1,4-Gal-T1 is most characterized (biochemically). It is a Golgi-resident type II membrane enzyme with a cytoplasmic domain, membrane spanning region, and a stem region and catalytic domain facing the lumen.
397018 Glyco_transf_7C 6.45e-23 165 234 1 71
N-terminal domain of galactosyltransferase. This is the N-terminal domain of a family of galactosyltransferases from a wide range of Metazoa with three related galactosyltransferases activities, all three of which are possessed by one sequence in some cases. EC:2.4.1.90, N-acetyllactosamine synthase; EC:2.4.1.38, Beta-N-acetylglucosaminyl-glycopeptide beta-1,4- galactosyltransferase; and EC:2.4.1.22 Lactose synthase. Note that N-acetyllactosamine synthase is a component of Lactose synthase along with alpha-lactalbumin, in the absence of alpha-lactalbumin EC:2.4.1.90 is the catalyzed reaction.
404599 Glyco_transf_7N 3.32e-19 64 159 47 132
N-terminal region of glycosyl transferase group 7. This is the N-terminal half of a family of galactosyltransferases from a wide range of Metazoa with three related galactosyltransferases activities, all three of which are possessed by one sequence in some cases. EC:2.4.1.90, N-acetyllactosamine synthase; EC:2.4.1.38, Beta-N-acetylglucosaminyl-glycopeptide beta-1,4- galactosyltransferase; and EC:2.4.1.22 Lactose synthase. Note that N-acetyllactosamine synthase is a component of Lactose synthase along with alpha-lactalbumin, in the absence of alpha-lactalbumin EC:2.4.1.90 is the catalyzed reaction.
133042 GT2_Chondriotin_Pol_N 1.33e-05 184 220 128 164
N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase. Chondroitin polymerase is a two domain, bi-functional protein. The N-terminal domain functions as a GalNAc transferase. The bacterial chondroitin polymerase catalyzes elongation of the chondroitin chain by alternatively transferring the GlcUA and GalNAc moiety from UDP-GlcUA and UDP-GalNAc to the non-reducing ends of the chondroitin chain. The enzyme consists of N-terminal and C-terminal domains in which the two active sites catalyze the addition of GalNAc and GlcUA, respectively. Chondroitin chains range from 40 to over 100 repeating units of the disaccharide. Sulfated chondroitins are involved in the regulation of various biological functions such as central nervous system development, wound repair, infection, growth factor signaling, and morphogenesis, in addition to its conventional structural roles. In Caenorhabditis elegans, chondroitin is an essential factor for the worm to undergo cytokinesis and cell division. Chondroitin is synthesized as proteoglycans, sulfated and secreted to the cell surface or extracellular matrix.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
3.10e-162 9 353 12 352
4.03e-33 66 285 540 759
4.03e-33 66 285 540 759
2.72e-32 66 292 149 369
7.79e-32 65 299 127 345

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2.65e-31 65 299 66 284
Human Lactose synthase: A 2:1 complex between human alpha-lactalbumin and human beta1,4-galactosyltransferase [Homo sapiens]
5.01e-31 65 299 65 283
Crystal structure of Lactose synthase complex with UDP [Bos taurus],1NHE_D Crystal structure of Lactose synthase complex with UDP [Bos taurus]
5.01e-31 65 299 65 283
Chain B, BETA-1,4-GALACTOSYLTRANSFERASE [Bos taurus],1NMM_D Chain D, BETA-1,4-GALACTOSYLTRANSFERASE [Bos taurus],1O0R_A Chain A, beta-1,4-galactosyltransferase [Bos taurus],1O0R_B Chain B, beta-1,4-galactosyltransferase [Bos taurus]
5.01e-31 65 299 65 283
Crystal Structure of Lactose Synthase, Complex with Glucose [Bos taurus],1NF5_D Crystal Structure of Lactose Synthase, Complex with Glucose [Bos taurus],1NKH_B Crystal structure of Lactose synthase complex with UDP and Manganese [Bos taurus],1NKH_D Crystal structure of Lactose synthase complex with UDP and Manganese [Bos taurus],1NQI_B crystal structure of lactose synthase, a 1:1 complex between beta1,4-galactosyltransferase and alpha-lactalbumin in the presence of GlcNAc [Bos taurus],1NQI_D crystal structure of lactose synthase, a 1:1 complex between beta1,4-galactosyltransferase and alpha-lactalbumin in the presence of GlcNAc [Bos taurus],1NWG_B Beta-1,4-Galactosyltransferase Complex With Alpha- Lactalbumin And N-Butanoyl-Glucoamine [Bos taurus],1NWG_D Beta-1,4-Galactosyltransferase Complex With Alpha- Lactalbumin And N-Butanoyl-Glucoamine [Bos taurus],1O23_B Crystal Structure Of Lactose Synthase In The Presence Of Udp-glucose [Bos taurus],1O23_D Crystal Structure Of Lactose Synthase In The Presence Of Udp-glucose [Bos taurus],1OQM_B A 1:1 complex between alpha-lactalbumin and beta1,4-galactosyltransferase in the presence of UDP-N-acetyl-galactosamine [Bos taurus],1OQM_D A 1:1 complex between alpha-lactalbumin and beta1,4-galactosyltransferase in the presence of UDP-N-acetyl-galactosamine [Bos taurus]
5.12e-31 65 299 66 284
Chain A, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AE7_B Chain B, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AE7_C Chain C, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AEC_A Chain A, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AEC_B Chain B, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AEC_C Chain C, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AES_A Chain A, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AES_B Chain B, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AES_C Chain C, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AGD_A Chain A, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AGD_B Chain B, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AGD_C Chain C, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AH9_A Chain A, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AH9_B Chain B, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2AH9_C Chain C, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2FY7_A Chain A, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2FYA_A Chain A, Beta-1,4-galactosyltransferase 1 [Homo sapiens],2FYB_A Chain A, Beta-1,4-galactosyltransferase 1 [Homo sapiens],3EE5_A Chain A, Beta-1,4-galactosyltransferase 1 [Homo sapiens],3EE5_B Chain B, Beta-1,4-galactosyltransferase 1 [Homo sapiens],3EE5_C Chain C, Beta-1,4-galactosyltransferase 1 [Homo sapiens],4EE3_A Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with pentasaccharide [Homo sapiens],4EE3_B Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with pentasaccharide [Homo sapiens],4EE3_C Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with pentasaccharide [Homo sapiens],4EE4_A Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with tetrasaccharide from Lacto-N-neohexose [Homo sapiens],4EE4_B Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with tetrasaccharide from Lacto-N-neohexose [Homo sapiens],4EE4_C Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with tetrasaccharide from Lacto-N-neohexose [Homo sapiens],4EE5_A Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with trisaccharide from Lacto-N-neotetraose [Homo sapiens],4EE5_B Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with trisaccharide from Lacto-N-neotetraose [Homo sapiens],4EE5_C Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with trisaccharide from Lacto-N-neotetraose [Homo sapiens],4EEA_A Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-Gal-Beta1,4-Glc-BETA [Homo sapiens],4EEA_B Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-Gal-Beta1,4-Glc-BETA [Homo sapiens],4EEA_C Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-Gal-Beta1,4-Glc-BETA [Homo sapiens],4EEG_A Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-Gal-Beta [Homo sapiens],4EEG_B Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-Gal-Beta [Homo sapiens],4EEG_C Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-Gal-Beta [Homo sapiens],4EEM_A Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-MAN-ALPHA-methyl [Homo sapiens],4EEM_B Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-MAN-ALPHA-methyl [Homo sapiens],4EEM_C Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-MAN-ALPHA-methyl [Homo sapiens],4EEO_A Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-GlcNAc-ALPHA-benzyl [Homo sapiens],4EEO_B Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-GlcNAc-ALPHA-benzyl [Homo sapiens],4EEO_C Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-GlcNAc-ALPHA-benzyl [Homo sapiens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4.06e-31 65 299 178 396
Beta-1,4-galactosyltransferase 1 OS=Mus musculus OX=10090 GN=B4galt1 PE=1 SV=1
8.20e-31 11 285 65 328
Beta-1,4-galactosyltransferase 4 OS=Mus musculus OX=10090 GN=B4galt4 PE=2 SV=1
2.19e-30 65 296 123 338
Beta-1,4-galactosyltransferase 4 OS=Cricetulus griseus OX=10029 GN=B4GALT4 PE=2 SV=1
3.04e-30 65 285 123 328
Beta-1,4-galactosyltransferase 4 OS=Rattus norvegicus OX=10116 GN=B4galt4 PE=2 SV=1
8.10e-30 65 285 123 328
Beta-1,4-galactosyltransferase 4 OS=Homo sapiens OX=9606 GN=B4GALT4 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
0.997602 0.002428

TMHMM  Annotations      help

There is no transmembrane helices in PPTG_04136-t26_2-p1.