CAZyme Information: PPTG_00683-t26_2-p1

Basic Information

• Species: Phytophthora parasitica
• Lineage: Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora parasitica
• CAZyme ID: PPTG_00683-t26_2-p1
• CAZy Family: AA17
• CAZyme Description: trehalose-phosphatase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
859		97567.18	6.0948

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PparasiticaINRA-310	23240	761204	119	23121

• Gene Location: location=KI669561:2674800-2677577(+)

Full Sequence      

MLAAEMEPELGESSLLDQLHDLHRRLAAVRQDSQRYTSLARNLGPIPMANDSNKIIVCSL
RRCVRMLKTERGDSWQYIPSATGLKSAIDYLGKGNTVRWVSWPGANVDESSQDGVRRRLE
TDFACHPVFLSHETVDLYQNQFCNVVLWPLFHSLPQRSDSRLLENFGEKYDAYCSANQKF
LEAVSEIYKDGDLVLVCDYQLMALPGLLRRRFPEITCGFYFHCPFPSSEFFQMLPVREAL
LHGVLGADLVVFNHFDYVRHFLNVCTRMLGLESSPSRVEYNGRLISLGICPMGIDPAKYA
LTPKVEANVEMLKRQQDGMKIIVGVHKLDFCKGIPEMLEAMEYLLQHYPEYRGKVVLYAV
VRDAGRTSSLQYRMLSRQINELVGRVNGKFGTAEYCPVRYLKQSIDHDQLVALYNCADVA
IVSSIKEGINLQAMEFIAAQKKSCHGVLVYSEFAGCASSFQGALLVNPMHIEQVAASVDT
ALRMNNTTKRIRHHQLSRYVNTYTSTLWAQRIMSALNEAAATAQEYNRLDKLDTAQLLGY
YERSQRRLFLLDYDGTLVNYQSMEELAEPSAALMSCLEDLTADPHNTVYIISGRNKNRLQ
EWFGHLPRVGLAAEHGYWFRPASKHPFKPNTDSGGDILTGRTSEDSPHTAESTLSTEENP
LASSSSSVIGSESAIRERAPWQCMFSDVELEWRDEVESILEHFTERTPGSLLDVKDCCYT
WHFRDADPTFGLKQAKDMQLHFDQMLRDLPVGVVMCRIKKYVMIRPWRVNKGRAVSRILE
YESETPYFTALDFDFILALGDERTDEDMFDVVQGSNCYTCTVGMKVSRAQYYLEDPDEVL
RVLTACTSLMAAERQPLSG

Enzyme Prediction     

No EC number prediction in PPTG_00683-t26_2-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT20	51	517	1.8e-151	0.9747368421052631

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
184712	PRK14501	0.0	69	848	15	725	putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional
340820	GT20_TPS	3.39e-173	54	517	1	463	trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.
215556	PLN03064	5.28e-164	69	848	108	931	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional
395781	Glyco_transf_20	5.01e-162	52	518	1	470	Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex,.
215555	PLN03063	1.64e-157	54	843	12	780	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ29132.1|GT20	0.0	9	859	14	876
CCA19773.1|GT20	0.0	11	857	25	923
CCA26754.1|GT20	0.0	11	857	25	923
QOX06485.1|GT20	9.86e-178	7	843	14	818
AJA04606.1|GT20	3.35e-177	10	843	63	873

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5HVM_A	6.89e-123	54	521	13	479	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVM_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
6JBI_A	4.59e-117	54	517	1	463	Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBI_B Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBR_A Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_B Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_D Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_F Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_H Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_K Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_M Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_O Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBW_A Structure of Tps1/UDP complex [Pyricularia oryzae 70-15],6JBW_B Structure of Tps1/UDP complex [Pyricularia oryzae 70-15]
5HVO_A	3.90e-116	53	521	11	479	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_C Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_D Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
5HUT_A	2.59e-107	54	516	5	467	Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUT_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUU_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HUU_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HVL_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314],5HVL_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314]
5HUV_A	1.00e-106	54	516	5	467	Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314],5HUV_B Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q54K57|TPSA_DICDI	1.45e-170	52	839	15	727	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] A OS=Dictyostelium discoideum OX=44689 GN=tpsA PE=2 SV=1
sp|Q54NU9|TPSB_DICDI	7.19e-137	99	843	98	784	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] B OS=Dictyostelium discoideum OX=44689 GN=tpsB PE=3 SV=1
sp|Q9LRA7|TPS9_ARATH	8.28e-135	54	859	61	855	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 9 OS=Arabidopsis thaliana OX=3702 GN=TPS9 PE=2 SV=1
sp|Q0WUI9|TPS8_ARATH	1.72e-134	83	843	95	831	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8 OS=Arabidopsis thaliana OX=3702 GN=TPS8 PE=2 SV=1
sp|O23617|TPS5_ARATH	2.43e-131	107	843	114	836	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 5 OS=Arabidopsis thaliana OX=3702 GN=TPS5 PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000043	0.000000

TMHMM  Annotations     

There is no transmembrane helices in PPTG_00683-t26_2-p1.