CAZyme Information: PMAA_087300-t26_1-p1

Basic Information

• Species: Talaromyces marneffei
• Lineage: Ascomycota; Eurotiomycetes; ; Trichocomaceae; Talaromyces; Talaromyces marneffei
• CAZyme ID: PMAA_087300-t26_1-p1
• CAZy Family: GH93
• CAZyme Description: glucose-methanol-choline (gmc) oxidoreductase, putative

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
679		72092.39	4.5457

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_TmarneffeiATCC18224	10194	441960	145	10049

• Gene Location: location=DS995901:2923828-2926173(-)

Full Sequence      

MRIASSIGVGLAVIAQVHALAPRTQVADEYDFVVVGGGQAGLVLGARLSEIANYTVLVLE
AGTNGDEYRHRIDTPAYSYYDSLWTTPMNWAYYTVPQSNADNRQIQWPRGKGLGGSSAIN
GLYMTRPGKDEINAWKDLLGDMDGADNWSWDSFYAALKKSETFTPPSDAIATEGNVTWDL
STRGTQGPIHASYPGYTFPEVGEWIQSLDAMGVASSSGMYGGDVYGAEVSTSSINPTNWT
RSYSRTGYLDPLADNGNYDVVADAFVMRLLFDSSSPLGNLTANGVQYTLDNGKTNCTVKV
NKEVIISAGTIGSPAVLLHSGVGPKDVLSDAGVKLVSELPGVGQHLQDHLSATIKWNTSV
VTSGSIFYQNLPDKNNTLYLSYIDSAIAYVNSTLMYGDKLGSLQKNITTQINSYALNITY
DAGVVAGFKAIANITATTILESSIGQIELLFMNSDSNGDIGITAALQHPYSHGRVYINSS
NPLDYPVIDPNYMGFSADYEILRDGLKLARQLGNTKPLSGCLTAEISPGPQVKTDDDWLD
WIRESAGSEFHPSSSCAMLPREQGGVVDANLRVYGLANVRVADASVVPISLSTHLMSSTY
GVAEQAGNIIRAYYTNTTTGTDGSGPGSTSPAGTVLGAHSTTSTAATPTAPSGGVQTVSV
VSAWVAVVLAASVSIFLSF

Enzyme Prediction     

No EC number prediction in PMAA_087300-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA3	29	611	9.4e-169	0.9929577464788732

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
225186	BetA	1.09e-94	26	612	4	535	Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only].
235000	PRK02106	5.05e-93	29	611	5	532	choline dehydrogenase; Validated
398739	GMC_oxred_C	3.68e-39	469	606	1	143	GMC oxidoreductase. This domain found associated with pfam00732.
366272	GMC_oxred_N	3.51e-20	98	350	12	217	GMC oxidoreductase. This family of proteins bind FAD as a cofactor.
215420	PLN02785	2.99e-15	30	354	56	332	Protein HOTHEAD

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QGA17100.1|AA3_2	0.0	1	679	1	679
QKX58234.1|AA3_2	0.0	18	617	19	619
QQK43025.1|AA3_2	4.59e-310	1	614	5	618
CCA74335.1|AA3_2	1.39e-198	28	625	44	629
QRV88352.1|AA3_2	6.83e-195	25	614	23	619

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6ZE2_A	2.41e-78	26	611	2	583	Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE2_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE3_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE4_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE4_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE5_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE5_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE6_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE6_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE7_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE7_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],7AA2_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],7AA2_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495]
6XUT_A	6.11e-77	22	612	9	589	Chain A, Oligosaccharide dehydrogenase [Trametes cinnabarina],6XUU_A Chain A, Oligosaccharide dehydrogenase [Trametes cinnabarina],6XUV_A Chain A, Oligosaccharide dehydrogenase [Trametes cinnabarina]
6O9N_A	7.88e-77	12	610	18	638	Structural insights on a new fungal aryl-alcohol oxidase [Thermothelomyces thermophilus],6O9N_B Structural insights on a new fungal aryl-alcohol oxidase [Thermothelomyces thermophilus]
4YNT_A	8.10e-73	30	611	6	565	Crystal structure of Aspergillus flavus FAD glucose dehydrogenase [Aspergillus flavus NRRL3357],4YNU_A Crystal structure of Aspergillus flavus FADGDH in complex with D-glucono-1,5-lactone [Aspergillus flavus NRRL3357]
4H7U_A	2.75e-61	29	614	40	601	Crystal structure of pyranose dehydrogenase from Agaricus meleagris, wildtype [Leucoagaricus meleagris]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q5GMY3|GMCH_MALSM	7.02e-148	29	610	46	615	GMC oxidoreductase family protein Mala s 12.0101 OS=Malassezia sympodialis OX=76777 PE=1 SV=2
sp|M5EAX2|GMCH_MALS4	7.02e-148	29	610	46	615	GMC oxidoreductase family protein Mala s 12 OS=Malassezia sympodialis (strain ATCC 42132) OX=1230383 GN=MSY001_2108 PE=1 SV=1
sp|Q5AUN2|XPTC_EMENI	1.53e-80	27	611	35	614	Dehydrogenase xptC OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=xptC PE=3 SV=1
sp|Q0CJ60|ATC_ASPTN	5.35e-69	29	604	45	587	Cyclase atC OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=atC PE=1 SV=1
sp|Q88AE7|BETA_PSESM	2.09e-68	28	611	5	536	Oxygen-dependent choline dehydrogenase OS=Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000) OX=223283 GN=betA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000441	0.999531	CS pos: 19-20. Pr: 0.9719

TMHMM  Annotations     

There is no transmembrane helices in PMAA_087300-t26_1-p1.