CAZyme Information: PMAA_053200-t26_1-p1

Basic Information

• Species: Talaromyces marneffei
• Lineage: Ascomycota; Eurotiomycetes; ; Trichocomaceae; Talaromyces; Talaromyces marneffei
• CAZyme ID: PMAA_053200-t26_1-p1
• CAZy Family: GH18
• CAZyme Description: 1,3-beta-glucanosyltransferase Gel2

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
478		50701.53	4.5675

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_TmarneffeiATCC18224	10194	441960	145	10049

• Gene Location: location=DS995903:830838-832442(-)

Full Sequence      

MVPSYAKLFAAVCGLASTAAAVNPVVVKGKDFVDTVTGDRFQIVGVDYQPGGSSGFKGTA
DPLSDKDACLRDAAILQYLGVNSIRVYNLAPSANHDECASIFNAAGIYMILDVNSPLDNG
SLNRGAPWESYNPVYMAQVFGVIEAFKNYPNTAGFFSGNEVINEDSVALVPNYIRAVQRD
MHDYISKNSKRPIPVGYSAADVRPLLVDSAYYFTCNLANSTNSRSDFFGLNSYSWCGDAT
YTTSGYNVLTEDFTNITVPVFFSETGCNNVRPRVFSEIQAIYGPDMSQALSGALVYEYTQ
EANDYGLVNLNSNGTVSLLVDFENLRSQYSKLDFSAITASNSSQTAITPPVCDPKQITSN
ITKSFRVPDRVDGIDDMIKNGVTKNVSVGALVSVSSTKINQTVYDSNGNIVTGLMLNVLS
NGAVNTPSNSTTVSSSGSRTGSSTGSSTSSSTTGAAVSARASALTGLGALTVMAFLAL

Enzyme Prediction     

EC	2.4.1.-:8

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH72	19	331	5.9e-119	0.9903846153846154

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397351	Glyco_hydro_72	1.95e-143	16	333	3	315	Glucanosyltransferase. This is a family of glycosylphosphatidylinositol-anchored beta(1-3)glucanosyltransferases. The active site residues in the Aspergillus fumigatus example are the two glutamate residues at 160 and 261.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QGA20659.1|GH72	1.20e-317	1	478	1	478
QKX53119.1|GH72	1.70e-218	3	416	770	1183
AAF40139.1|GH72|2.4.1.-	2.02e-193	1	427	1	425
EAL88984.1|GH72	2.02e-193	1	427	1	425
BCS09515.1|GH72	1.39e-191	1	427	1	427

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2W62_A	1.29e-72	27	338	38	349	Saccharomyces cerevisiae Gas2p in complex with laminaripentaose [Saccharomyces cerevisiae],2W63_A Saccharomyces Cerevisiae Gas2p In Complex With Laminaritriose And Laminaritetraose [Saccharomyces cerevisiae],5O9O_A Crystal structure of ScGas2 in complex with compound 7. [Saccharomyces cerevisiae S288C],5O9P_A Crystal structure of Gas2 in complex with compound 10 [Saccharomyces cerevisiae S288C],5O9Q_A Crystal structure of ScGas2 in complex with compound 6 [Saccharomyces cerevisiae S288C],5O9R_A Crystal structure of ScGas2 in complex with compound 9 [Saccharomyces cerevisiae S288C],5O9Y_A Crystal structure of ScGas2 in complex with compound 11 [Saccharomyces cerevisiae S288C],5OA2_A Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_B Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_C Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA6_A Crystal structure of ScGas2 in complex with compound 12 [Saccharomyces cerevisiae S288C]
2W61_A	3.54e-72	27	338	38	349	Saccharomyces cerevisiae Gas2p apostructure (E176Q mutant) [Saccharomyces cerevisiae]
5FIH_A	3.54e-72	27	338	38	349	SACCHAROMYCES CEREVISIAE GAS2P (E176Q MUTANT) IN COMPLEX WITH LAMINARITETRAOSE AND LAMINARIPENTAOSE [Saccharomyces cerevisiae]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P0C954|GEL2_ASPFU	3.60e-194	1	427	1	425	1,3-beta-glucanosyltransferase gel2 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gel2 PE=3 SV=1
sp|B0Y8H9|GEL2_ASPFC	3.60e-194	1	427	1	425	1,3-beta-glucanosyltransferase gel2 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=gel2 PE=1 SV=1
sp|Q08271|GAS4_YEAST	4.22e-102	20	408	21	406	1,3-beta-glucanosyltransferase GAS4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GAS4 PE=1 SV=1
sp|Q03655|GAS3_YEAST	4.64e-96	8	382	8	403	Probable 1,3-beta-glucanosyltransferase GAS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GAS3 PE=1 SV=1
sp|Q5AJY5|PGA4_CANAL	7.60e-91	15	373	12	358	1,3-beta-glucanosyltransferase PGA4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PGA4 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000426	0.999512	CS pos: 21-22. Pr: 0.9604

TMHMM  Annotations     

There is no transmembrane helices in PMAA_053200-t26_1-p1.