CAZyme Information: PMAA_016710-t26_1-p1

Basic Information

• Species: Talaromyces marneffei
• Lineage: Ascomycota; Eurotiomycetes; ; Trichocomaceae; Talaromyces; Talaromyces marneffei
• CAZyme ID: PMAA_016710-t26_1-p1
• CAZy Family: AA9
• CAZyme Description: mannosyltransferase (PIG-M), putative

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
430	DS995899|CGC18	48681.25	9.7023

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_TmarneffeiATCC18224	10194	441960	145	10049

• Gene Location: location=DS995899:383856-385284(-)

Full Sequence      

MPSPFSSPAVIFSLAALMRVGLLFYGLYQDNHSAMKYTDIDYMVFTDASRFMAEGQSPYL
RDTYRYTPLLAWFLIPTTWEPNWLWFSFGKVLFAIADLVTGWLLLLVLRTEFPGMSEKSR
LRYASIWLLNPMVATISTRGSSEGLLGVMVIALLWAVLNRHTIFASFLLGLGVHFKIYPF
IYAPSIIWFLSPTSAPTSSMIRKILNFITFDRIKVTIISLLTFIGLNVWMYSLYGHSFLQ
HTYFHHLTRIDHRHNFSPYNTLLYLSAATEDVGAAARGIKFESVAFVPQLFLSAFAIPLA
LAKKSLPGAMLAQTFAFVTFNKVCTSQYFLWYLVFLPLYLPSSSFINNPILGVGALVMWI
LSQAFWLHQGFQLEFMGLSTFLPGLWLASLGFFIVNCWILGIIVSDIGGWPAKALQARNE
GSQTAKQKNQ

Enzyme Prediction     

EC	2.4.1.-:14

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT50	136	403	1e-93	0.9923664122137404

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
178434	PLN02841	3.24e-83	1	404	1	415	GPI mannosyltransferase
252941	Mannosyl_trans	9.45e-70	136	404	1	259	Mannosyltransferase (PIG-M). PIG-M has a DXD motif. The DXD motif is found in many glycosyltransferases that utilize nucleotide sugars. It is thought that the motif is involved in the binding of a manganese ion that is required for association of the enzymes with nucleotide sugar substrates.
399599	PIG-U	1.32e-07	55	248	47	243	GPI transamidase subunit PIG-U. Many eukaryotic proteins are anchored to the cell surface via glycosylphosphatidylinositol (GPI), which is posttranslationally attached to the carboxyl-terminus by GPI transamidase. The mammalian GPI transamidase is a complex of at least four subunits, GPI8, GAA1, PIG-S, and PIG-T. PIG-U is thought to represent a fifth subunit in this complex and may be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QGA12480.1|GT50	9.79e-313	1	430	1	430
QKX64577.1|GT50	4.75e-228	1	408	1	416
QSS50664.1|GT50	7.63e-180	1	421	1	428
QSS62928.1|GT50	2.18e-179	1	421	1	428
QSS74503.1|GT50	3.09e-179	1	421	1	428

PDB Hits     

PMAA_016710-t26_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q5B7W0|GPI14_EMENI	9.65e-179	1	409	1	430	GPI mannosyltransferase 1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=gpi14 PE=3 SV=1
sp|Q2TXB8|GPI14_ASPOR	2.76e-176	1	407	1	410	GPI mannosyltransferase 1 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=gpi14 PE=3 SV=2
sp|Q4I073|GPI14_GIBZE	1.17e-174	1	406	1	407	GPI mannosyltransferase 1 OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=GPI14 PE=3 SV=1
sp|Q4WAH2|GPI14_ASPFU	2.49e-167	1	409	1	423	GPI mannosyltransferase 1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gpi14 PE=3 SV=1
sp|Q7S4Z3|GPI14_NEUCR	2.78e-164	5	408	23	486	GPI mannosyltransferase 1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=gim-1 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000008	0.000010

TMHMM  Annotations     

Start	End
5	27
83	105
136	158
165	187
217	239
284	301
316	338
345	367
382	404