CAZyme Information: PITG_20927-t26_1-p1

Basic Information

• Species: Phytophthora infestans
• Lineage: Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora infestans
• CAZyme ID: PITG_20927-t26_1-p1
• CAZy Family: PL1
• CAZyme Description: trehalose-phosphatase, putative

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
825		93826.28	6.6981

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PinfestansT30-4	19344	403677	1547	17797

• Gene Location: location=DS028318:79285-82035(+)

Full Sequence      

MSEMGESSLLDQLHDLHRRLAAVRQDSQRYTSLGPIPMANDSNKIIVCSLRRCVRMLKTQ
RGDSWQYIPSATGLKSAIDYLGKGNTVRWVSWPGANVDESSQDGVRRRLETDFACHPVFL
GHETLDLYQNQFCNVVLWPLFHSLPQRSDSRLLENFGEKYDAYCSANQKFLEAVSEIYKD
GDLVLVCDYQLMALPGLLRRRFPEITCGFYFHCPFPSSEFFQMLPVREALLHGVLGADLV
VFNHFDYVRHFLNVCTRMLGLESSPSRVEYNGRLISLGICPMGIDPVKYALTAKVETHVE
ILKRQQDGMKIIVGVHKLDFCKGIPEMLEAMEYLLQHYPEYRGKVVLYAVVRDAGRTASL
QYRMLSRQINEFVGRVNGRFGTAEYCPVRYLKQSIEHSQLVALYNCADVAIVSSIKEGIN
LQAMEFIAAQKKSCHGVLVYSEFAGCASSFQGALLVNPMHIEQVAASVDTALRMNSTTKR
IRHHQLSRYVTTYTSTLWAQRIMSALNEAAATAQEYNRLDKLDTAQLLGYYERSQRRLFL
LDYDGTLVNYQSMEELAEPSAALMSCLEDLTATPHNTVYIISGRNKNRLQEWFGHLPRVG
LAAEHGYWFRPASKHPSTLSTDKSPLASSSSSAMGSESVANFERAPWQCMFSDVELEWRD
EVESILEHFTERTPGSLLDVKDCCYTWHFRDADPTFGLKQAKDMQLHFDQMLRDLPVGVV
MCRIKKYVMIRPWRVNKGRAVSRILEYESETPYFTALDFDFILALGDERTDEDMFDVVQG
SNCYTCTVGMKVSRAQYYLEGPDEVLRVLTACTSLMAADRQPLSG

Enzyme Prediction     

No EC number prediction in PITG_20927-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT20	41	507	1.1e-148	0.9747368421052631

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
184712	PRK14501	0.0	59	814	15	725	putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional
340820	GT20_TPS	1.45e-169	44	507	1	463	trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.
215556	PLN03064	7.55e-165	59	814	108	931	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional
215555	PLN03063	1.27e-157	44	809	12	780	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional
395781	Glyco_transf_20	5.05e-157	63	508	22	470	Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex,.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ29132.1|GT20	0.0	1	825	12	876
CCA19773.1|GT20	0.0	5	823	25	923
CCA26754.1|GT20	0.0	5	823	25	923
AJA04606.1|GT20	1.37e-175	2	809	61	873
AGT80036.1|GT20	1.37e-175	2	809	61	873

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5HVM_A	1.60e-118	44	511	13	479	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVM_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
6JBI_A	9.99e-114	60	507	14	463	Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBI_B Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBR_A Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_B Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_D Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_F Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_H Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_K Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_M Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_O Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBW_A Structure of Tps1/UDP complex [Pyricularia oryzae 70-15],6JBW_B Structure of Tps1/UDP complex [Pyricularia oryzae 70-15]
5HVO_A	3.30e-112	43	511	11	479	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_C Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_D Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
5HUV_A	2.05e-104	44	506	5	467	Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314],5HUV_B Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314]
5HUT_A	2.05e-104	44	506	5	467	Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUT_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUU_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HUU_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HVL_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314],5HVL_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q54K57|TPSA_DICDI	5.18e-171	42	805	15	727	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] A OS=Dictyostelium discoideum OX=44689 GN=tpsA PE=2 SV=1
sp|Q54NU9|TPSB_DICDI	3.06e-136	89	809	98	784	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] B OS=Dictyostelium discoideum OX=44689 GN=tpsB PE=3 SV=1
sp|Q0WUI9|TPS8_ARATH	6.82e-135	73	809	95	831	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8 OS=Arabidopsis thaliana OX=3702 GN=TPS8 PE=2 SV=1
sp|Q9LRA7|TPS9_ARATH	1.36e-133	95	825	112	855	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 9 OS=Arabidopsis thaliana OX=3702 GN=TPS9 PE=2 SV=1
sp|Q9LMI0|TPS7_ARATH	3.75e-132	26	809	42	830	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 7 OS=Arabidopsis thaliana OX=3702 GN=TPS7 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000042	0.000000

TMHMM  Annotations     

There is no transmembrane helices in PITG_20927-t26_1-p1.