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CAZyme Information: PITG_11935-t26_1-p1

You are here: Home > Sequence: PITG_11935-t26_1-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phytophthora infestans
Lineage Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora infestans
CAZyme ID PITG_11935-t26_1-p1
CAZy Family GH47
CAZyme Description conserved hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
396 DS028138|CGC3 42571.46 6.9498
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_PinfestansT30-4 19344 403677 1547 17797
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in PITG_11935-t26_1-p1.

CAZyme Signature Domains help

Family Start End Evalue family coverage
AA17 257 383 1.3e-22 0.4775510204081633

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
215230 PLN02418 2.81e-22 102 161 631 690
delta-1-pyrroline-5-carboxylate synthase
143398 ALDH_F18-19_ProA-GPR 1.79e-21 104 159 342 397
Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19. Gamma-glutamyl phosphate reductase (GPR), a L-proline biosynthetic pathway (PBP) enzyme that catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The glutamate route of the PBP involves two enzymatic steps catalyzed by gamma-glutamyl kinase (GK, EC 2.7.2.11) and GPR (EC 1.2.1.41). These enzymes are fused into the bifunctional enzyme, ProA or delta(1)-pyrroline-5-carboxylate synthetase (P5CS) in plants and animals, whereas they are separate enzymes in bacteria and yeast. In humans, the P5CS (ALDH18A1), an inner mitochondrial membrane enzyme, is essential to the de novo synthesis of the amino acids proline and arginine. Tomato (Lycopersicon esculentum) has both the prokaryotic-like polycistronic operons encoding GK and GPR (PRO1, ALDH19) and the full-length, bifunctional P5CS (PRO2, ALDH18B1).
223093 ProA 8.52e-20 79 159 324 403
Gamma-glutamyl phosphate reductase [Amino acid transport and metabolism].
234685 proA 2.00e-19 102 158 346 402
gamma-glutamyl phosphate reductase; Provisional
130164 P5CS 1.85e-18 79 159 603 682
delta l-pyrroline-5-carboxylate synthetase. This protein contains a glutamate 5-kinase (ProB, EC 2.7.2.11) region followed by a gamma-glutamyl phosphate reductase (ProA, EC 1.2.1.41) region. [Amino acid biosynthesis, Glutamate family]

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
1.34e-247 1 396 1 396
1.36e-31 258 324 147 214
1.36e-31 258 324 147 214
1.42e-31 258 324 147 214
1.42e-31 258 324 147 214

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3.13e-14 75 162 664 747
Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5T_B Chain B, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5T_C Chain C, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5T_D Chain D, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5U_A Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5U_B Chain B, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5U_C Chain C, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5U_D Chain D, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5V_A Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5V_B Chain B, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5V_C Chain C, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5V_D Chain D, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5X_A Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5X_B Chain B, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5X_C Chain C, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7F5X_D Chain D, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX3_A Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX3_B Chain B, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX3_C Chain C, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX3_D Chain D, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX3_E Chain E, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX3_F Chain F, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX3_G Chain G, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX3_H Chain H, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX4_A Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WX4_E Chain E, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WXF_A Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WXF_B Chain B, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WXG_A Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WXH_A Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WXH_B Chain B, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WXI_A Chain A, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster],7WXI_B Chain B, Delta-1-pyrroline-5-carboxylate synthase [Drosophila melanogaster]
1.58e-12 68 162 329 429
Crystal structure of human pyrroline-5-carboxylate synthetase [Homo sapiens],2H5G_B Crystal structure of human pyrroline-5-carboxylate synthetase [Homo sapiens]
8.37e-09 67 162 343 434
Crystal structure of Gamma-glutamyl phosphate reductase (yor323c) from Saccharomyces cerevisiae at 2.40 A resolution [Saccharomyces cerevisiae],1VLU_B Crystal structure of Gamma-glutamyl phosphate reductase (yor323c) from Saccharomyces cerevisiae at 2.40 A resolution [Saccharomyces cerevisiae]
1.06e-08 53 166 318 437
X-ray Crystal Structure of Gamma-glutamyl phosphate reductase from Burkholderia thailandensis [Burkholderia thailandensis E264],4GHK_B X-ray Crystal Structure of Gamma-glutamyl phosphate reductase from Burkholderia thailandensis [Burkholderia thailandensis E264],4GHK_C X-ray Crystal Structure of Gamma-glutamyl phosphate reductase from Burkholderia thailandensis [Burkholderia thailandensis E264],4GHK_D X-ray Crystal Structure of Gamma-glutamyl phosphate reductase from Burkholderia thailandensis [Burkholderia thailandensis E264]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.57e-13 61 159 597 706
Delta-1-pyrroline-5-carboxylate synthase 2 OS=Oryza sativa subsp. japonica OX=39947 GN=P5CS2 PE=2 SV=1
2.18e-13 104 162 699 757
Probable delta-1-pyrroline-5-carboxylate synthase OS=Caenorhabditis elegans OX=6239 GN=alh-13 PE=3 SV=2
8.63e-13 79 159 607 686
Delta-1-pyrroline-5-carboxylate synthase OS=Mesembryanthemum crystallinum OX=3544 GN=P5CS PE=2 SV=1
1.15e-12 72 162 591 690
Delta-1-pyrroline-5-carboxylate synthase OS=Solanum lycopersicum OX=4081 GN=PRO2 PE=2 SV=1
1.53e-12 79 159 608 687
Delta-1-pyrroline-5-carboxylate synthase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=P5CS1 PE=2 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000061 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in PITG_11935-t26_1-p1.