CAZyme Information: PITG_11558-t26_1-p1

Basic Information

• Species: Phytophthora infestans
• Lineage: Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora infestans
• CAZyme ID: PITG_11558-t26_1-p1
• CAZy Family: GH47
• CAZyme Description: beta-glucan synthesis-associated protein, putative

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
676		74926.06	4.9321

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PinfestansT30-4	19344	403677	1547	17797

• Gene Location: location=DS028139:345899-347999(-)

Full Sequence      

MSDEFNTPGRSFRPGDDHLWTSIEKPDGVNDAMEVYAHNKTTTVCDEVHDVCSFQIELED
SVLQLQVWNSYLQTPGFENVTFFYRGGMVQSWNKFCIQGGMVEVRAQLPGALSEESGNPD
IRLDESARVRSLRYYPTWPGIWMMGNLGRAIFSGSTNRMWPFSYDACDPDTFTPANQRIN
ACESHPGSGLNPHQGRGAPEIDIVEGGGTTISASIQVGPGMPPDFRVIPPEDENKLCIYS
SSCETPGSNVPGIPESVYLSARGHPSWYQNMRYAANNFCLQNVSETQRYTTVQAALSAGI
EDNVCSVTTCPASLDISSDLDYIHVEGDDRWGINSNGTCFSAMNSYMGEFICSAGNSDPS
CHPRDDAPVLPQDDSSFAFQMDALSANWPVHMAAYTDWVQYQVEWVSGPHGCVRWMLSGE
PLYEIPAKTITEPPQGASVKNPSKIMIEEPMYLIFNVAMSSKWGAQPPNPKNVCRGDGLD
PVANAICDAFPMYLKLDYIRVYQDLSPGSLMSVGCDPSTHPTRRWILDHLDEYEDEENKL
VEVRGKAFCRTDADCTVQTAHRRAHGPRSTFVRTGRCLNRRCECVSKSWAGPRCIVPTTS
SGVSFGPPLVLAACMGALLFVLGVASSVAICFARKKDAEAVQTERKVKQQQRQQYERMRR
QSSQHLQSAWSSEISL

Enzyme Prediction     

EC	-	-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH16	3	221	2.2e-61	0.5858895705521472

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397841	SKN1	6.86e-57	2	535	122	478	Beta-glucan synthesis-associated protein (SKN1). This family consists of the beta-glucan synthesis-associated proteins KRE6 and SKN1. Beta1,6-Glucan is a key component of the yeast cell wall, interconnecting cell wall proteins, beta1,3-glucan, and chitin. It has been postulated that the synthesis of beta1,6-glucan begins in the endoplasmic reticulum with the formation of protein-bound primer structures and that these primer structures are extended in the Golgi complex by two putative glucosyltransferases that are functionally redundant, Kre6 and Skn1. This is followed by maturation steps at the cell surface and by coupling to other cell wall macromolecules.
185689	GH16_fungal_KRE6_glucanase	1.05e-45	2	503	4	295	Saccharomyces cerevisiae KRE6 and related glucanses, member of glycosyl hydrolase family 16. KRE6 is a Saccharomyces cerevisiae glucanase that participates in the synthesis of beta-1,6-glucan, a major structural component of the cell wall. It is a golgi membrane protein required for normal beta-1,6-glucan levels in the cell wall. KRE6 is closely realted to laminarinase, a glycosyl hydrolase family 16 member that hydrolyzes 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans such as laminarins, curdlans, paramylons, and pachymans, with very limited action on mixed-link (1,3-1,4-)-beta-D-glucans.
225182	BglS	1.18e-10	72	322	91	317	Beta-glucanase, GH16 family [Carbohydrate transport and metabolism].
185693	GH16_laminarinase_like	7.31e-07	401	502	163	235	Laminarinase, member of the glycosyl hydrolase family 16. Laminarinase, also known as glucan endo-1,3-beta-D-glucosidase, is a glycosyl hydrolase family 16 member that hydrolyzes 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans such as laminarins, curdlans, paramylons, and pachymans, with very limited action on mixed-link (1,3-1,4-)-beta-D-glucans.
185693	GH16_laminarinase_like	1.24e-05	2	220	2	138	Laminarinase, member of the glycosyl hydrolase family 16. Laminarinase, also known as glucan endo-1,3-beta-D-glucosidase, is a glycosyl hydrolase family 16 member that hydrolyzes 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans such as laminarins, curdlans, paramylons, and pachymans, with very limited action on mixed-link (1,3-1,4-)-beta-D-glucans.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ24235.1|GH16_2	0.0	1	673	62	735
UIZ28149.1|GH16	2.27e-266	1	639	62	707
UIZ28151.1|GH16	7.44e-265	1	642	63	716
UIZ28152.1|GH16	7.16e-254	1	612	51	670
UIZ27810.1|GH16	8.25e-253	1	622	98	727

PDB Hits     

PITG_11558-t26_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P32486|KRE6_YEAST	4.12e-33	1	548	330	702	Beta-glucan synthesis-associated protein KRE6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=KRE6 PE=1 SV=2
sp|P87023|KRE6_CANAX	1.03e-29	1	548	355	732	Beta-glucan synthesis-associated protein KRE6 OS=Candida albicans OX=5476 GN=KRE6 PE=2 SV=1
sp|P33336|SKN1_YEAST	3.47e-29	1	548	382	754	Beta-glucan synthesis-associated protein SKN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SKN1 PE=1 SV=1
sp|P87024|SKN1_CANAX	3.81e-26	1	548	359	729	Beta-glucan synthesis-associated protein SKN1 OS=Candida albicans OX=5476 GN=SKN1 PE=2 SV=1
sp|O13789|YEOB_SCHPO	1.16e-25	1	533	247	612	Uncharacterized beta-glucan synthesis-associated protein C17G6.11c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC17G6.11c PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000082	0.000002

TMHMM  Annotations     

Start	End
609	631