CAZyme Information: PITG_02432-t26_1-p1

Basic Information

• Species: Phytophthora infestans
• Lineage: Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora infestans
• CAZyme ID: PITG_02432-t26_1-p1
• CAZy Family: AA6
• CAZyme Description: dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase, putative

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
569		65541.91	9.0578

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PinfestansT30-4	19344	403677	1547	17797

• Gene Location: location=DS028120:2049441-2051212(-)

Full Sequence      

MARKKTSTSTSTSKTKRATRIDKDVKTTLMHSRVLSFLYDLMWSYRYFPQLACCLLLVEA
CVGYLIIQKVPYTEIDWSTYMQQVELFKAGERDYMQIRGDTGPLVYPAGFLYVFSFLHSI
TDNGQNIQRAQYIFLGFYLIMIATVLAIYYRARVLPPWATVFLCTSKRLHSIFMLRMFND
GVAMMLLFIAVYLFARQRWRWGCVFFSLAVSIKMNVLLFAPALFFLLLQSCGILRTAWYL
VICAAIQVALAYPFLKHNWWNYMNKAFELSRVFTFKWTVNWRFLDEETFVSGGFAIILLL
GHLFFMVLFLDKHFNIIGTIRAVMMKPFAIYEPFPIQSEIVVTSLFVMNFAGIVFSRTLH
YQFYSWYYPTLPYLLWCSDLPLLLKMAALLNNEYAFNTFPSTTMSSLMLQLTNTFLLITL
YLNQKNNSFIPYLDAEARTNLIAFVNEECFDGARQLVLYYGSVTEDLAEGATVSSIDEHE
VVLSLPKMKLTLAVGFGSSGPVTGEGYGRQVLKDMLKEAGEGVKAGDTMGKLINREYIKD
KELKNLVGSLDEEHDSKTSLRQRTTTKTR

Enzyme Prediction     

EC	2.4.1.258:18

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT58	53	406	1.2e-135	0.9945054945054945

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
398745	ALG3	0.0	55	406	3	358	ALG3 protein. The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man. ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.
227829	COG5542	0.005	158	284	150	276	Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ28023.1|GT58	0.0	10	568	5	565
CCA23790.1|GT58	1.69e-253	13	542	6	535
SVE76345.1|GT58	4.54e-106	55	421	52	413
SVE84217.1|GT58	4.54e-106	55	421	52	413
SVE85454.1|GT58	1.80e-105	55	421	52	413

PDB Hits     

PITG_02432-t26_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q55F69|ALG3_DICDI	2.42e-110	29	428	1	429	Probable Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Dictyostelium discoideum OX=44689 GN=alg3 PE=3 SV=1
sp|Q8K2A8|ALG3_MOUSE	6.26e-102	39	426	33	426	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg3 PE=1 SV=2
sp|Q92685|ALG3_HUMAN	2.16e-99	46	422	40	422	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG3 PE=1 SV=1
sp|O82244|ALG3_ARATH	7.23e-90	55	422	39	417	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Arabidopsis thaliana OX=3702 GN=ALG3 PE=1 SV=1
sp|P82149|NT53_DROME	4.73e-82	49	413	46	477	Lethal(2)neighbour of tid protein 2 OS=Drosophila melanogaster OX=7227 GN=l(2)not2 PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999968	0.000032

TMHMM  Annotations     

Start	End
45	67
103	120
133	152
172	194
201	223
233	255
288	310
334	356
363	385
400	422